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Updated November 2019
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Protein Info
Short Name:
COL27A1
Full Name:
Collagen alpha-1(XXVII) chain
Alias:
collagen, type XXVII, alpha 1; CORA1; FLJ11895; KIAA1870; MGC11337; RP11-82I1.1
Type:
Mass (Da):
186892
Number AA:
1860
UniProt ID:
Q8IZC6
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005581
Uniprot
OncoNet
Molecular Function:
GO:0005201
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
S
A
R
G
A
R
G
T
A
A
A
A
A
A
R
Site 2
S38
S
F
A
C
H
L
A
S
T
Q
G
A
P
E
D
Site 3
S55
I
L
Q
R
L
G
L
S
W
T
K
A
G
S
P
Site 4
T57
Q
R
L
G
L
S
W
T
K
A
G
S
P
A
P
Site 5
T77
F
Q
S
G
F
I
F
T
Q
R
A
R
L
Q
A
Site 6
S119
A
F
L
F
A
V
R
S
Q
K
R
K
L
Q
L
Site 7
S141
K
T
V
V
H
L
G
S
R
R
S
V
A
F
D
Site 8
S144
V
H
L
G
S
R
R
S
V
A
F
D
L
D
M
Site 9
S196
P
A
L
D
P
G
G
S
F
L
F
G
K
M
N
Site 10
T241
K
Q
C
G
Q
A
D
T
Y
Q
S
P
L
G
P
Site 11
Y242
Q
C
G
Q
A
D
T
Y
Q
S
P
L
G
P
L
Site 12
S244
G
Q
A
D
T
Y
Q
S
P
L
G
P
L
F
S
Site 13
S251
S
P
L
G
P
L
F
S
Q
D
S
G
R
P
F
Site 14
S254
G
P
L
F
S
Q
D
S
G
R
P
F
T
F
Q
Site 15
T259
Q
D
S
G
R
P
F
T
F
Q
S
D
L
A
L
Site 16
S281
T
A
T
P
A
L
G
S
L
P
A
G
R
G
P
Site 17
T291
A
G
R
G
P
R
G
T
V
A
P
A
T
P
T
Site 18
T296
R
G
T
V
A
P
A
T
P
T
K
P
Q
R
T
Site 19
S304
P
T
K
P
Q
R
T
S
P
T
N
P
H
Q
H
Site 20
S340
L
D
P
M
L
P
A
S
V
G
G
S
T
R
T
Site 21
S344
L
P
A
S
V
G
G
S
T
R
T
P
R
P
A
Site 22
T347
S
V
G
G
S
T
R
T
P
R
P
A
A
A
Q
Site 23
S356
R
P
A
A
A
Q
P
S
Q
K
I
T
A
T
K
Site 24
T360
A
Q
P
S
Q
K
I
T
A
T
K
I
P
K
S
Site 25
T362
P
S
Q
K
I
T
A
T
K
I
P
K
S
L
P
Site 26
S367
T
A
T
K
I
P
K
S
L
P
T
K
P
S
A
Site 27
T370
K
I
P
K
S
L
P
T
K
P
S
A
P
S
T
Site 28
S373
K
S
L
P
T
K
P
S
A
P
S
T
S
I
V
Site 29
S376
P
T
K
P
S
A
P
S
T
S
I
V
P
I
K
Site 30
T377
T
K
P
S
A
P
S
T
S
I
V
P
I
K
S
Site 31
S378
K
P
S
A
P
S
T
S
I
V
P
I
K
S
P
Site 32
S384
T
S
I
V
P
I
K
S
P
H
P
T
Q
K
T
Site 33
T388
P
I
K
S
P
H
P
T
Q
K
T
A
P
S
S
Site 34
T391
S
P
H
P
T
Q
K
T
A
P
S
S
F
T
K
Site 35
S394
P
T
Q
K
T
A
P
S
S
F
T
K
S
A
L
Site 36
S395
T
Q
K
T
A
P
S
S
F
T
K
S
A
L
P
Site 37
S399
A
P
S
S
F
T
K
S
A
L
P
T
Q
K
Q
Site 38
T403
F
T
K
S
A
L
P
T
Q
K
Q
V
P
P
T
Site 39
T410
T
Q
K
Q
V
P
P
T
S
R
P
V
P
A
R
Site 40
S411
Q
K
Q
V
P
P
T
S
R
P
V
P
A
R
V
Site 41
S419
R
P
V
P
A
R
V
S
R
P
A
E
K
P
I
Site 42
S439
M
P
R
P
P
P
P
S
T
R
P
L
P
P
T
Site 43
T440
P
R
P
P
P
P
S
T
R
P
L
P
P
T
T
Site 44
T446
S
T
R
P
L
P
P
T
T
S
S
S
K
K
P
Site 45
T447
T
R
P
L
P
P
T
T
S
S
S
K
K
P
I
Site 46
S448
R
P
L
P
P
T
T
S
S
S
K
K
P
I
P
Site 47
S449
P
L
P
P
T
T
S
S
S
K
K
P
I
P
T
Site 48
S450
L
P
P
T
T
S
S
S
K
K
P
I
P
T
L
Site 49
T456
S
S
K
K
P
I
P
T
L
A
R
T
E
A
K
Site 50
T460
P
I
P
T
L
A
R
T
E
A
K
I
T
S
H
Site 51
T465
A
R
T
E
A
K
I
T
S
H
A
S
K
P
A
Site 52
S466
R
T
E
A
K
I
T
S
H
A
S
K
P
A
S
Site 53
S469
A
K
I
T
S
H
A
S
K
P
A
S
A
R
T
Site 54
S473
S
H
A
S
K
P
A
S
A
R
T
S
T
H
K
Site 55
S477
K
P
A
S
A
R
T
S
T
H
K
P
P
P
F
Site 56
T478
P
A
S
A
R
T
S
T
H
K
P
P
P
F
T
Site 57
T485
T
H
K
P
P
P
F
T
A
L
S
S
S
P
A
Site 58
S488
P
P
P
F
T
A
L
S
S
S
P
A
P
T
P
Site 59
S489
P
P
F
T
A
L
S
S
S
P
A
P
T
P
G
Site 60
S490
P
F
T
A
L
S
S
S
P
A
P
T
P
G
S
Site 61
T494
L
S
S
S
P
A
P
T
P
G
S
T
R
S
T
Site 62
S497
S
P
A
P
T
P
G
S
T
R
S
T
R
P
P
Site 63
S500
P
T
P
G
S
T
R
S
T
R
P
P
A
T
M
Site 64
T501
T
P
G
S
T
R
S
T
R
P
P
A
T
M
V
Site 65
T506
R
S
T
R
P
P
A
T
M
V
P
P
T
S
G
Site 66
T511
P
A
T
M
V
P
P
T
S
G
T
S
T
P
R
Site 67
S512
A
T
M
V
P
P
T
S
G
T
S
T
P
R
T
Site 68
T516
P
P
T
S
G
T
S
T
P
R
T
A
P
A
V
Site 69
T519
S
G
T
S
T
P
R
T
A
P
A
V
P
T
P
Site 70
T525
R
T
A
P
A
V
P
T
P
G
S
A
P
T
G
Site 71
S528
P
A
V
P
T
P
G
S
A
P
T
G
S
K
K
Site 72
T531
P
T
P
G
S
A
P
T
G
S
K
K
P
I
G
Site 73
S533
P
G
S
A
P
T
G
S
K
K
P
I
G
S
E
Site 74
S539
G
S
K
K
P
I
G
S
E
A
S
K
K
A
G
Site 75
S549
S
K
K
A
G
P
K
S
S
P
R
K
P
V
P
Site 76
S550
K
K
A
G
P
K
S
S
P
R
K
P
V
P
L
Site 77
S569
A
A
R
D
V
P
L
S
D
L
T
T
R
P
S
Site 78
T572
D
V
P
L
S
D
L
T
T
R
P
S
P
R
Q
Site 79
T573
V
P
L
S
D
L
T
T
R
P
S
P
R
Q
P
Site 80
S576
S
D
L
T
T
R
P
S
P
R
Q
P
Q
P
S
Site 81
S583
S
P
R
Q
P
Q
P
S
Q
Q
T
T
P
A
L
Site 82
T587
P
Q
P
S
Q
Q
T
T
P
A
L
V
L
A
P
Site 83
S599
L
A
P
A
Q
F
L
S
S
S
P
R
P
T
S
Site 84
S600
A
P
A
Q
F
L
S
S
S
P
R
P
T
S
S
Site 85
S601
P
A
Q
F
L
S
S
S
P
R
P
T
S
S
G
Site 86
T605
L
S
S
S
P
R
P
T
S
S
G
Y
S
I
F
Site 87
S606
S
S
S
P
R
P
T
S
S
G
Y
S
I
F
H
Site 88
S607
S
S
P
R
P
T
S
S
G
Y
S
I
F
H
L
Site 89
S610
R
P
T
S
S
G
Y
S
I
F
H
L
A
G
S
Site 90
Y660
P
R
G
P
P
G
P
Y
G
N
P
G
L
P
G
Site 91
S681
Q
K
G
D
P
G
L
S
P
G
K
A
H
D
G
Site 92
S699
D
M
G
L
P
G
L
S
G
N
P
G
P
P
G
Site 93
Y713
G
R
K
G
H
K
G
Y
P
G
P
A
G
H
P
Site 94
S731
G
Q
P
G
P
E
G
S
P
G
A
K
G
Y
P
Site 95
Y737
G
S
P
G
A
K
G
Y
P
G
R
Q
G
L
P
Site 96
S755
G
D
P
G
P
K
G
S
R
G
Y
I
G
L
P
Site 97
Y758
G
P
K
G
S
R
G
Y
I
G
L
P
G
L
F
Site 98
S770
G
L
F
G
L
P
G
S
D
G
E
R
G
L
P
Site 99
Y833
G
V
L
G
P
I
G
Y
P
G
P
K
G
M
K
Site 100
S845
G
M
K
G
L
M
G
S
V
G
E
P
G
L
K
Site 101
S864
E
Q
G
V
P
G
V
S
G
D
P
G
F
Q
G
Site 102
S875
G
F
Q
G
D
K
G
S
Q
G
L
P
G
F
P
Site 103
S899
G
K
V
G
D
K
G
S
I
G
F
P
G
P
P
Site 104
S1028
G
V
P
G
P
K
G
S
M
G
H
P
G
M
P
Site 105
T1040
G
M
P
G
G
M
G
T
P
G
E
P
G
P
Q
Site 106
S1052
G
P
Q
G
P
P
G
S
R
G
P
P
G
M
R
Site 107
S1109
G
E
R
G
H
L
G
S
R
G
F
P
G
I
P
Site 108
S1119
F
P
G
I
P
G
P
S
G
P
P
G
T
K
G
Site 109
T1175
G
D
L
G
P
L
G
T
P
G
E
Q
G
L
I
Site 110
S1194
E
P
G
L
E
G
D
S
G
P
M
G
P
D
G
Site 111
T1236
P
P
G
P
P
G
V
T
G
V
R
G
P
E
G
Site 112
S1245
V
R
G
P
E
G
K
S
G
K
Q
G
E
K
G
Site 113
T1254
K
Q
G
E
K
G
R
T
G
A
K
G
A
K
G
Site 114
T1280
G
D
P
G
P
P
G
T
P
G
P
K
G
S
R
Site 115
S1286
G
T
P
G
P
K
G
S
R
G
S
L
G
P
T
Site 116
S1289
G
P
K
G
S
R
G
S
L
G
P
T
G
A
P
Site 117
T1293
S
R
G
S
L
G
P
T
G
A
P
G
R
M
G
Site 118
Y1310
G
E
P
G
L
A
G
Y
D
G
H
K
G
I
V
Site 119
Y1365
G
E
P
G
D
P
G
Y
P
G
Q
E
G
V
Q
Site 120
S1398
G
W
P
G
P
K
G
S
K
G
A
E
G
P
K
Site 121
S1495
P
P
G
F
K
G
E
S
G
L
P
G
Q
L
G
Site 122
T1509
G
P
P
G
K
R
G
T
E
G
R
T
G
L
P
Site 123
S1524
G
N
Q
G
E
P
G
S
K
G
Q
P
G
D
S
Site 124
S1531
S
K
G
Q
P
G
D
S
G
E
M
G
F
P
G
Site 125
S1593
G
P
K
G
D
K
G
S
R
G
D
W
G
L
Q
Site 126
S1647
S
G
A
L
R
P
E
S
Y
S
Y
P
D
R
L
Site 127
Y1648
G
A
L
R
P
E
S
Y
S
Y
P
D
R
L
V
Site 128
S1649
A
L
R
P
E
S
Y
S
Y
P
D
R
L
V
L
Site 129
Y1650
L
R
P
E
S
Y
S
Y
P
D
R
L
V
L
D
Site 130
T1665
Q
G
G
E
I
F
K
T
L
H
Y
L
S
N
L
Site 131
Y1668
E
I
F
K
T
L
H
Y
L
S
N
L
I
Q
S
Site 132
S1670
F
K
T
L
H
Y
L
S
N
L
I
Q
S
I
K
Site 133
T1678
N
L
I
Q
S
I
K
T
P
L
G
T
K
E
N
Site 134
Y1705
Q
K
M
V
D
G
T
Y
W
V
D
P
N
L
G
Site 135
S1715
D
P
N
L
G
C
S
S
D
T
I
E
V
S
C
Site 136
T1717
N
L
G
C
S
S
D
T
I
E
V
S
C
N
F
Site 137
S1721
S
S
D
T
I
E
V
S
C
N
F
T
H
G
G
Site 138
T1780
W
Q
E
G
T
G
Q
T
P
A
K
Q
A
V
R
Site 139
T1824
R
W
H
Q
T
L
F
T
F
R
T
Q
D
P
Q
Site 140
T1827
Q
T
L
F
T
F
R
T
Q
D
P
Q
Q
L
P
Site 141
S1845
V
D
N
L
P
P
A
S
S
G
K
Q
Y
R
L
Site 142
Y1850
P
A
S
S
G
K
Q
Y
R
L
E
V
G
P
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation