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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DCP1B
Full Name:
mRNA-decapping enzyme 1B
Alias:
DCP1 decapping enzyme B; Decapping enzyme hDcp1b; FLJ31638
Type:
Hydrolase; EC 3.-.-.-; RNA binding protein
Mass (Da):
67851
Number AA:
618
UniProt ID:
Q8IZD4
International Prot ID:
IPI00328309
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0016787
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0000184
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
V
G
K
G
R
D
I
S
L
A
A
L
Q
R
H
Site 2
Y27
A
L
Q
R
H
D
P
Y
I
N
R
I
V
D
V
Site 3
T42
A
S
Q
V
A
L
Y
T
F
G
H
R
A
N
E
Site 4
T53
R
A
N
E
W
E
K
T
D
V
E
G
T
L
F
Site 5
Y62
V
E
G
T
L
F
V
Y
T
R
S
A
S
P
K
Site 6
T63
E
G
T
L
F
V
Y
T
R
S
A
S
P
K
H
Site 7
S67
F
V
Y
T
R
S
A
S
P
K
H
G
F
T
I
Site 8
T73
A
S
P
K
H
G
F
T
I
M
N
R
L
S
M
Site 9
S79
F
T
I
M
N
R
L
S
M
E
N
R
T
E
P
Site 10
T88
E
N
R
T
E
P
I
T
K
D
L
D
F
Q
L
Site 11
Y102
L
Q
D
P
F
L
L
Y
R
N
A
R
L
S
I
Site 12
Y110
R
N
A
R
L
S
I
Y
G
I
W
F
Y
D
K
Site 13
Y115
S
I
Y
G
I
W
F
Y
D
K
E
E
C
Q
R
Site 14
T131
A
E
L
M
K
N
L
T
Q
Y
E
Q
L
K
A
Site 15
Y133
L
M
K
N
L
T
Q
Y
E
Q
L
K
A
H
Q
Site 16
T142
Q
L
K
A
H
Q
G
T
G
A
G
I
S
P
V
Site 17
S147
Q
G
T
G
A
G
I
S
P
V
I
L
N
S
G
Site 18
S153
I
S
P
V
I
L
N
S
G
E
G
K
E
V
D
Site 19
Y172
L
I
K
A
K
D
E
Y
T
K
C
K
T
C
S
Site 20
T173
I
K
A
K
D
E
Y
T
K
C
K
T
C
S
E
Site 21
S186
S
E
P
K
K
I
T
S
S
S
A
I
Y
D
N
Site 22
S188
P
K
K
I
T
S
S
S
A
I
Y
D
N
P
N
Site 23
Y191
I
T
S
S
S
A
I
Y
D
N
P
N
L
I
K
Site 24
T218
R
I
P
Q
P
N
Q
T
L
D
P
E
P
Q
H
Site 25
S227
D
P
E
P
Q
H
L
S
L
T
A
L
F
G
K
Site 26
T239
F
G
K
Q
D
K
A
T
C
Q
E
T
V
E
P
Site 27
T243
D
K
A
T
C
Q
E
T
V
E
P
P
Q
T
L
Site 28
T249
E
T
V
E
P
P
Q
T
L
H
Q
Q
Q
Q
Q
Site 29
S274
I
R
Q
G
V
V
R
S
L
S
Y
E
E
P
R
Site 30
S276
Q
G
V
V
R
S
L
S
Y
E
E
P
R
R
H
Site 31
Y277
G
V
V
R
S
L
S
Y
E
E
P
R
R
H
S
Site 32
S284
Y
E
E
P
R
R
H
S
P
P
I
E
K
Q
L
Site 33
S309
S
A
D
L
H
P
L
S
E
L
P
E
N
R
P
Site 34
S321
N
R
P
C
E
N
G
S
T
H
S
A
G
E
F
Site 35
T322
R
P
C
E
N
G
S
T
H
S
A
G
E
F
F
Site 36
S337
T
G
P
V
Q
P
G
S
P
H
N
I
G
T
S
Site 37
T343
G
S
P
H
N
I
G
T
S
R
G
V
Q
N
A
Site 38
S362
N
L
F
E
K
L
Q
S
T
P
G
A
A
N
K
Site 39
T363
L
F
E
K
L
Q
S
T
P
G
A
A
N
K
C
Site 40
S373
A
A
N
K
C
D
P
S
T
P
A
P
A
S
S
Site 41
T374
A
N
K
C
D
P
S
T
P
A
P
A
S
S
A
Site 42
S379
P
S
T
P
A
P
A
S
S
A
A
L
N
R
S
Site 43
S380
S
T
P
A
P
A
S
S
A
A
L
N
R
S
R
Site 44
S386
S
S
A
A
L
N
R
S
R
A
P
T
S
V
T
Site 45
T390
L
N
R
S
R
A
P
T
S
V
T
P
V
A
P
Site 46
S391
N
R
S
R
A
P
T
S
V
T
P
V
A
P
G
Site 47
T393
S
R
A
P
T
S
V
T
P
V
A
P
G
K
G
Site 48
Y408
L
A
Q
P
P
Q
A
Y
F
N
G
S
L
P
P
Site 49
S412
P
Q
A
Y
F
N
G
S
L
P
P
Q
T
V
G
Site 50
T417
N
G
S
L
P
P
Q
T
V
G
H
Q
A
H
G
Site 51
S428
Q
A
H
G
R
E
Q
S
T
L
P
R
Q
T
L
Site 52
T434
Q
S
T
L
P
R
Q
T
L
P
I
S
G
S
Q
Site 53
S438
P
R
Q
T
L
P
I
S
G
S
Q
T
G
S
S
Site 54
S440
Q
T
L
P
I
S
G
S
Q
T
G
S
S
G
V
Site 55
S444
I
S
G
S
Q
T
G
S
S
G
V
I
S
P
Q
Site 56
S445
S
G
S
Q
T
G
S
S
G
V
I
S
P
Q
E
Site 57
S449
T
G
S
S
G
V
I
S
P
Q
E
L
L
K
K
Site 58
S469
Q
E
Q
Q
L
H
A
S
N
R
P
A
L
A
A
Site 59
T498
L
E
S
W
I
N
K
T
P
N
T
E
Q
Q
T
Site 60
T501
W
I
N
K
T
P
N
T
E
Q
Q
T
P
L
F
Site 61
T505
T
P
N
T
E
Q
Q
T
P
L
F
Q
V
I
S
Site 62
T535
P
M
V
F
A
Q
P
T
S
V
P
P
K
E
R
Site 63
S536
M
V
F
A
Q
P
T
S
V
P
P
K
E
R
E
Site 64
S544
V
P
P
K
E
R
E
S
G
L
L
P
V
G
G
Site 65
S571
P
I
Q
S
P
E
P
S
V
I
T
S
S
P
L
Site 66
T574
S
P
E
P
S
V
I
T
S
S
P
L
T
K
L
Site 67
S575
P
E
P
S
V
I
T
S
S
P
L
T
K
L
Q
Site 68
S576
E
P
S
V
I
T
S
S
P
L
T
K
L
Q
L
Site 69
Y589
Q
L
Q
E
A
L
L
Y
L
I
Q
N
D
D
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation