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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HS6ST3
Full Name:
Heparan-sulfate 6-O-sulfotransferase 3
Alias:
Type:
Membrane protein
Mass (Da):
54844
Number AA:
471
UniProt ID:
Q8IZP7
International Prot ID:
IPI00218046
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0008146
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T31
Q
Y
V
S
P
S
C
T
S
S
C
T
N
F
G
Site 2
S33
V
S
P
S
C
T
S
S
C
T
N
F
G
E
Q
Site 3
S119
P
E
A
P
E
N
G
S
L
P
R
F
V
P
R
Site 4
S130
F
V
P
R
F
N
F
S
L
K
D
L
T
R
F
Site 5
T135
N
F
S
L
K
D
L
T
R
F
V
D
F
N
I
Site 6
T156
V
F
L
H
I
Q
K
T
G
G
T
T
F
G
R
Site 7
T160
I
Q
K
T
G
G
T
T
F
G
R
H
L
V
K
Site 8
S176
I
R
L
E
Q
P
C
S
C
K
A
G
Q
K
K
Site 9
S198
K
K
E
T
W
L
F
S
R
F
S
T
G
W
S
Site 10
Y239
H
S
H
T
R
N
F
Y
Y
I
T
M
L
R
D
Site 11
Y240
S
H
T
R
N
F
Y
Y
I
T
M
L
R
D
P
Site 12
S249
T
M
L
R
D
P
V
S
R
Y
L
S
E
W
K
Site 13
Y251
L
R
D
P
V
S
R
Y
L
S
E
W
K
H
V
Site 14
S253
D
P
V
S
R
Y
L
S
E
W
K
H
V
Q
R
Site 15
T263
K
H
V
Q
R
G
A
T
W
K
T
S
L
H
M
Site 16
S275
L
H
M
C
D
G
R
S
P
T
P
D
E
L
P
Site 17
T277
M
C
D
G
R
S
P
T
P
D
E
L
P
T
C
Site 18
T283
P
T
P
D
E
L
P
T
C
Y
P
G
D
D
W
Site 19
Y285
P
D
E
L
P
T
C
Y
P
G
D
D
W
S
G
Site 20
S291
C
Y
P
G
D
D
W
S
G
V
S
L
R
E
F
Site 21
Y303
R
E
F
M
D
C
T
Y
N
L
A
N
N
R
Q
Site 22
Y323
D
L
S
L
V
G
C
Y
N
L
T
F
M
N
E
Site 23
T326
L
V
G
C
Y
N
L
T
F
M
N
E
S
E
R
Site 24
S331
N
L
T
F
M
N
E
S
E
R
N
T
I
L
L
Site 25
T335
M
N
E
S
E
R
N
T
I
L
L
Q
S
A
K
Site 26
T360
L
T
E
F
Q
R
K
T
Q
F
L
F
E
R
T
Site 27
S385
Q
F
N
I
T
R
A
S
N
V
E
I
N
E
G
Site 28
Y408
N
F
L
D
M
Q
L
Y
E
Y
A
K
D
L
F
Site 29
Y410
L
D
M
Q
L
Y
E
Y
A
K
D
L
F
Q
Q
Site 30
Y419
K
D
L
F
Q
Q
R
Y
H
H
T
K
Q
L
E
Site 31
T461
G
A
A
E
G
T
V
T
E
D
Y
N
S
Q
V
Site 32
Y464
E
G
T
V
T
E
D
Y
N
S
Q
V
V
R
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation