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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPR64
Full Name:
G-protein coupled receptor 64
Alias:
EDDM6; epididymal protein 6; epididymis-specific protein 6; G protein-coupled receptor 64; HE6; He6 receptor; TM7LN2
Type:
Receptor, GPCR
Mass (Da):
111593
Number AA:
1017
UniProt ID:
Q8IZP9
International Prot ID:
IPI00024754
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0004930
PhosphoSite+
KinaseNET
Biological Process:
GO:0007218
GO:0007283
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T42
V
T
S
L
E
E
D
T
D
N
S
S
L
S
P
Site 2
S45
L
E
E
D
T
D
N
S
S
L
S
P
P
P
A
Site 3
S46
E
E
D
T
D
N
S
S
L
S
P
P
P
A
K
Site 4
S48
D
T
D
N
S
S
L
S
P
P
P
A
K
L
S
Site 5
S62
S
V
V
S
F
A
P
S
S
N
G
T
P
E
V
Site 6
S63
V
V
S
F
A
P
S
S
N
G
T
P
E
V
E
Site 7
T66
F
A
P
S
S
N
G
T
P
E
V
E
T
T
S
Site 8
S73
T
P
E
V
E
T
T
S
L
N
D
V
T
L
S
Site 9
T78
T
T
S
L
N
D
V
T
L
S
L
L
P
S
N
Site 10
S80
S
L
N
D
V
T
L
S
L
L
P
S
N
E
T
Site 11
S84
V
T
L
S
L
L
P
S
N
E
T
E
K
T
K
Site 12
T90
P
S
N
E
T
E
K
T
K
I
T
I
V
K
T
Site 13
Y130
R
G
E
I
M
F
Q
Y
D
K
E
S
T
V
P
Site 14
S152
G
T
L
T
G
V
L
S
L
S
E
L
K
R
S
Site 15
S159
S
L
S
E
L
K
R
S
E
L
N
K
T
L
Q
Site 16
T164
K
R
S
E
L
N
K
T
L
Q
T
L
S
E
T
Site 17
T188
A
Q
S
T
L
N
C
T
F
T
I
K
L
N
N
Site 18
S227
S
V
R
I
P
C
P
S
S
P
E
E
L
E
K
Site 19
S228
V
R
I
P
C
P
S
S
P
E
E
L
E
K
L
Site 20
S256
H
P
R
G
P
P
F
S
S
S
Q
S
I
P
V
Site 21
S257
P
R
G
P
P
F
S
S
S
Q
S
I
P
V
V
Site 22
S258
R
G
P
P
F
S
S
S
Q
S
I
P
V
V
P
Site 23
S260
P
P
F
S
S
S
Q
S
I
P
V
V
P
R
A
Site 24
S271
V
P
R
A
T
V
L
S
Q
V
P
K
A
T
S
Site 25
S278
S
Q
V
P
K
A
T
S
F
A
E
P
P
D
Y
Site 26
Y285
S
F
A
E
P
P
D
Y
S
P
V
T
H
N
V
Site 27
S286
F
A
E
P
P
D
Y
S
P
V
T
H
N
V
P
Site 28
T289
P
P
D
Y
S
P
V
T
H
N
V
P
S
P
I
Site 29
S294
P
V
T
H
N
V
P
S
P
I
G
E
I
Q
P
Site 30
S303
I
G
E
I
Q
P
L
S
P
Q
P
S
A
P
I
Site 31
S307
Q
P
L
S
P
Q
P
S
A
P
I
A
S
S
P
Site 32
S313
P
S
A
P
I
A
S
S
P
A
I
D
M
P
P
Site 33
S322
A
I
D
M
P
P
Q
S
E
T
I
S
S
P
M
Site 34
S326
P
P
Q
S
E
T
I
S
S
P
M
P
Q
T
H
Site 35
S327
P
Q
S
E
T
I
S
S
P
M
P
Q
T
H
V
Site 36
T332
I
S
S
P
M
P
Q
T
H
V
S
G
T
P
P
Site 37
S335
P
M
P
Q
T
H
V
S
G
T
P
P
P
V
K
Site 38
T337
P
Q
T
H
V
S
G
T
P
P
P
V
K
A
S
Site 39
S344
T
P
P
P
V
K
A
S
F
S
S
P
T
V
S
Site 40
S346
P
P
V
K
A
S
F
S
S
P
T
V
S
A
P
Site 41
T349
K
A
S
F
S
S
P
T
V
S
A
P
A
N
V
Site 42
S351
S
F
S
S
P
T
V
S
A
P
A
N
V
N
T
Site 43
S372
Q
T
D
I
V
N
T
S
S
I
S
D
L
E
N
Site 44
S373
T
D
I
V
N
T
S
S
I
S
D
L
E
N
Q
Site 45
S389
L
Q
M
E
K
A
L
S
L
G
S
L
E
P
N
Site 46
S392
E
K
A
L
S
L
G
S
L
E
P
N
L
A
G
Site 47
S406
G
E
M
I
N
Q
V
S
R
L
L
H
S
P
P
Site 48
S411
Q
V
S
R
L
L
H
S
P
P
D
M
L
A
P
Site 49
T439
L
Q
L
N
F
S
N
T
T
I
S
L
T
S
P
Site 50
S442
N
F
S
N
T
T
I
S
L
T
S
P
S
L
A
Site 51
T464
A
S
S
F
N
T
T
T
F
V
A
Q
D
P
A
Site 52
S476
D
P
A
N
L
Q
V
S
L
E
T
Q
A
P
E
Site 53
T490
E
N
S
I
G
T
I
T
L
P
S
S
L
M
N
Site 54
T517
V
Q
F
N
F
F
E
T
P
A
L
F
Q
D
P
Site 55
T544
S
S
S
V
A
N
L
T
V
R
N
L
T
R
N
Site 56
T553
R
N
L
T
R
N
V
T
V
T
L
K
H
I
N
Site 57
T555
L
T
R
N
V
T
V
T
L
K
H
I
N
P
S
Site 58
S562
T
L
K
H
I
N
P
S
Q
D
E
L
T
V
R
Site 59
S585
N
G
G
R
G
G
W
S
D
N
G
C
S
V
K
Site 60
T599
K
D
R
R
L
N
E
T
I
C
T
C
S
H
L
Site 61
T602
R
L
N
E
T
I
C
T
C
S
H
L
T
S
F
Site 62
Y660
F
E
K
I
R
R
D
Y
P
S
K
I
L
I
Q
Site 63
S662
K
I
R
R
D
Y
P
S
K
I
L
I
Q
L
C
Site 64
T729
A
L
V
K
V
F
N
T
Y
I
R
K
Y
I
L
Site 65
Y761
L
T
I
S
P
D
N
Y
G
L
G
S
Y
G
K
Site 66
S765
P
D
N
Y
G
L
G
S
Y
G
K
F
P
N
G
Site 67
T827
Q
L
G
A
Q
R
K
T
S
I
Q
D
L
R
S
Site 68
S828
L
G
A
Q
R
K
T
S
I
Q
D
L
R
S
I
Site 69
Y893
V
R
K
Q
W
R
R
Y
L
C
C
G
K
L
R
Site 70
S905
K
L
R
L
A
E
N
S
D
W
S
K
T
A
T
Site 71
T910
E
N
S
D
W
S
K
T
A
T
N
G
L
K
K
Site 72
T912
S
D
W
S
K
T
A
T
N
G
L
K
K
Q
T
Site 73
T919
T
N
G
L
K
K
Q
T
V
N
Q
G
V
S
S
Site 74
S926
T
V
N
Q
G
V
S
S
S
S
N
S
L
Q
S
Site 75
S927
V
N
Q
G
V
S
S
S
S
N
S
L
Q
S
S
Site 76
S928
N
Q
G
V
S
S
S
S
N
S
L
Q
S
S
S
Site 77
S930
G
V
S
S
S
S
N
S
L
Q
S
S
S
N
S
Site 78
S933
S
S
S
N
S
L
Q
S
S
S
N
S
T
N
S
Site 79
S934
S
S
N
S
L
Q
S
S
S
N
S
T
N
S
T
Site 80
S935
S
N
S
L
Q
S
S
S
N
S
T
N
S
T
T
Site 81
S937
S
L
Q
S
S
S
N
S
T
N
S
T
T
L
L
Site 82
T938
L
Q
S
S
S
N
S
T
N
S
T
T
L
L
V
Site 83
S940
S
S
S
N
S
T
N
S
T
T
L
L
V
N
N
Site 84
T941
S
S
N
S
T
N
S
T
T
L
L
V
N
N
D
Site 85
S950
L
L
V
N
N
D
C
S
V
H
A
S
G
N
G
Site 86
S954
N
D
C
S
V
H
A
S
G
N
G
N
A
S
T
Site 87
S960
A
S
G
N
G
N
A
S
T
E
R
N
G
V
S
Site 88
T961
S
G
N
G
N
A
S
T
E
R
N
G
V
S
F
Site 89
S967
S
T
E
R
N
G
V
S
F
S
V
Q
N
G
D
Site 90
S969
E
R
N
G
V
S
F
S
V
Q
N
G
D
V
C
Site 91
T1005
G
R
M
A
L
R
R
T
S
K
R
G
S
L
H
Site 92
S1006
R
M
A
L
R
R
T
S
K
R
G
S
L
H
F
Site 93
S1010
R
R
T
S
K
R
G
S
L
H
F
I
E
Q
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation