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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR17
Full Name:
WD repeat-containing protein 17
Alias:
Type:
Mass (Da):
147703
Number AA:
1322
UniProt ID:
Q8IZU2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y17
W
F
E
Q
D
D
W
Y
E
G
L
Q
R
A
N
Site 2
S26
G
L
Q
R
A
N
M
S
Q
V
R
Q
V
G
L
Site 3
Y64
A
T
L
A
I
Y
I
Y
Q
L
D
H
R
Y
N
Site 4
Y70
I
Y
Q
L
D
H
R
Y
N
E
F
K
L
H
A
Site 5
T85
I
M
S
E
H
K
K
T
I
T
A
I
S
W
C
Site 6
S101
H
N
P
D
L
F
A
S
G
S
T
D
N
L
V
Site 7
S124
K
V
I
A
K
L
D
S
T
K
G
I
P
A
S
Site 8
T155
R
G
P
L
F
I
W
T
I
S
G
P
D
S
G
Site 9
S161
W
T
I
S
G
P
D
S
G
V
I
V
H
K
D
Site 10
S199
G
H
I
D
G
S
L
S
I
F
H
P
G
N
K
Site 11
S216
K
H
V
L
R
P
E
S
L
E
G
T
D
E
E
Site 12
T220
R
P
E
S
L
E
G
T
D
E
E
D
P
V
T
Site 13
T227
T
D
E
E
D
P
V
T
A
L
E
W
D
P
L
Site 14
S279
Q
C
L
A
W
V
P
S
A
P
G
M
F
I
T
Site 15
T303
I
W
N
V
S
R
T
T
P
I
D
N
L
K
L
Site 16
T313
D
N
L
K
L
K
K
T
G
F
H
C
L
H
V
Site 17
S323
H
C
L
H
V
L
N
S
P
P
R
K
K
F
S
Site 18
S330
S
P
P
R
K
K
F
S
V
Q
S
P
T
K
N
Site 19
S333
R
K
K
F
S
V
Q
S
P
T
K
N
H
Y
T
Site 20
Y339
Q
S
P
T
K
N
H
Y
T
S
S
T
S
E
A
Site 21
T340
S
P
T
K
N
H
Y
T
S
S
T
S
E
A
V
Site 22
T351
S
E
A
V
P
P
P
T
L
T
Q
N
Q
A
F
Site 23
T353
A
V
P
P
P
T
L
T
Q
N
Q
A
F
S
L
Site 24
S359
L
T
Q
N
Q
A
F
S
L
P
P
G
H
A
V
Site 25
Y377
L
D
G
G
V
G
L
Y
D
M
G
A
K
K
W
Site 26
Y430
I
N
T
L
T
A
V
Y
T
S
P
G
N
E
G
Site 27
Y440
P
G
N
E
G
V
I
Y
S
L
S
W
A
P
G
Site 28
S441
G
N
E
G
V
I
Y
S
L
S
W
A
P
G
G
Site 29
T498
K
D
S
K
R
I
A
T
C
S
S
D
G
F
C
Site 30
Y518
D
G
K
V
L
H
K
Y
K
H
P
A
A
V
F
Site 31
Y549
E
D
T
N
V
R
V
Y
Y
V
A
T
S
S
D
Site 32
Y550
D
T
N
V
R
V
Y
Y
V
A
T
S
S
D
Q
Site 33
S575
K
V
F
H
V
K
W
S
P
L
R
E
G
I
L
Site 34
S584
L
R
E
G
I
L
C
S
G
S
D
D
G
T
V
Site 35
S586
E
G
I
L
C
S
G
S
D
D
G
T
V
R
I
Site 36
Y632
L
I
S
G
S
W
D
Y
T
I
K
V
W
D
T
Site 37
T647
R
E
G
T
C
V
D
T
V
Y
D
H
G
A
D
Site 38
Y649
G
T
C
V
D
T
V
Y
D
H
G
A
D
V
Y
Site 39
Y656
Y
D
H
G
A
D
V
Y
G
L
T
C
H
P
S
Site 40
T659
G
A
D
V
Y
G
L
T
C
H
P
S
R
P
F
Site 41
S663
Y
G
L
T
C
H
P
S
R
P
F
T
M
A
S
Site 42
T667
C
H
P
S
R
P
F
T
M
A
S
C
S
R
D
Site 43
S670
S
R
P
F
T
M
A
S
C
S
R
D
S
T
V
Site 44
S672
P
F
T
M
A
S
C
S
R
D
S
T
V
R
L
Site 45
S675
M
A
S
C
S
R
D
S
T
V
R
L
W
S
L
Site 46
T676
A
S
C
S
R
D
S
T
V
R
L
W
S
L
T
Site 47
S698
I
N
I
L
A
D
R
S
W
E
E
I
I
G
N
Site 48
Y708
E
I
I
G
N
T
D
Y
A
I
E
P
G
T
P
Site 49
T714
D
Y
A
I
E
P
G
T
P
P
L
L
C
G
K
Site 50
S737
I
E
K
L
T
A
N
S
Q
V
K
K
L
R
W
Site 51
S746
V
K
K
L
R
W
F
S
E
C
L
S
P
P
G
Site 52
S750
R
W
F
S
E
C
L
S
P
P
G
G
S
D
N
Site 53
S771
V
I
K
G
Q
D
D
S
L
L
P
Q
N
Y
C
Site 54
Y777
D
S
L
L
P
Q
N
Y
C
K
G
I
M
H
L
Site 55
S793
H
L
I
K
F
R
T
S
E
A
Q
E
L
T
T
Site 56
T800
S
E
A
Q
E
L
T
T
V
K
M
S
K
F
G
Site 57
Y835
R
L
G
Q
I
Q
R
Y
C
E
L
M
V
E
L
Site 58
Y859
A
P
G
V
S
V
K
Y
W
K
K
L
M
Q
R
Site 59
S923
N
M
Q
P
L
H
V
S
V
P
K
G
A
S
Y
Site 60
S931
V
P
K
G
A
S
Y
S
D
D
I
Y
K
E
D
Site 61
Y935
A
S
Y
S
D
D
I
Y
K
E
D
F
N
E
L
Site 62
S947
N
E
L
L
H
K
V
S
K
E
L
A
E
W
Y
Site 63
Y954
S
K
E
L
A
E
W
Y
F
Q
D
G
R
A
V
Site 64
T1078
H
D
K
C
K
L
P
T
V
E
E
C
M
Q
L
Site 65
T1098
A
D
D
N
I
F
E
T
V
K
Y
Y
L
L
S
Site 66
Y1101
N
I
F
E
T
V
K
Y
Y
L
L
S
Q
E
P
Site 67
S1105
T
V
K
Y
Y
L
L
S
Q
E
P
E
K
A
L
Site 68
Y1122
G
I
S
F
V
K
E
Y
I
S
S
S
D
W
T
Site 69
S1124
S
F
V
K
E
Y
I
S
S
S
D
W
T
L
D
Site 70
S1125
F
V
K
E
Y
I
S
S
S
D
W
T
L
D
T
Site 71
S1126
V
K
E
Y
I
S
S
S
D
W
T
L
D
T
I
Site 72
T1129
Y
I
S
S
S
D
W
T
L
D
T
I
Y
P
V
Site 73
T1154
K
L
L
L
H
T
C
T
E
A
R
N
E
L
L
Site 74
S1179
A
I
R
R
Q
Y
Q
S
I
V
P
A
L
Y
E
Site 75
Y1187
I
V
P
A
L
Y
E
Y
T
S
Q
L
L
K
R
Site 76
S1189
P
A
L
Y
E
Y
T
S
Q
L
L
K
R
R
E
Site 77
S1198
L
L
K
R
R
E
V
S
V
P
L
K
I
E
Y
Site 78
Y1205
S
V
P
L
K
I
E
Y
L
S
E
E
L
D
A
Site 79
T1217
L
D
A
W
R
A
C
T
Q
S
T
N
R
S
L
Site 80
S1219
A
W
R
A
C
T
Q
S
T
N
R
S
L
E
D
Site 81
S1223
C
T
Q
S
T
N
R
S
L
E
D
S
P
Y
T
Site 82
S1227
T
N
R
S
L
E
D
S
P
Y
T
P
P
S
D
Site 83
Y1229
R
S
L
E
D
S
P
Y
T
P
P
S
D
S
Q
Site 84
T1230
S
L
E
D
S
P
Y
T
P
P
S
D
S
Q
R
Site 85
S1233
D
S
P
Y
T
P
P
S
D
S
Q
R
M
I
Y
Site 86
S1235
P
Y
T
P
P
S
D
S
Q
R
M
I
Y
A
T
Site 87
Y1240
S
D
S
Q
R
M
I
Y
A
T
L
L
K
R
L
Site 88
T1242
S
Q
R
M
I
Y
A
T
L
L
K
R
L
K
E
Site 89
S1251
L
K
R
L
K
E
E
S
L
K
G
I
I
G
P
Site 90
Y1260
K
G
I
I
G
P
D
Y
V
T
G
S
N
L
P
Site 91
T1262
I
I
G
P
D
Y
V
T
G
S
N
L
P
S
H
Site 92
S1264
G
P
D
Y
V
T
G
S
N
L
P
S
H
S
D
Site 93
S1268
V
T
G
S
N
L
P
S
H
S
D
I
H
I
S
Site 94
S1270
G
S
N
L
P
S
H
S
D
I
H
I
S
C
L
Site 95
S1294
F
F
L
E
D
G
K
S
A
I
S
L
N
D
A
Site 96
S1297
E
D
G
K
S
A
I
S
L
N
D
A
L
M
W
Site 97
S1311
W
A
K
V
N
P
F
S
P
L
G
T
G
I
R
Site 98
T1315
N
P
F
S
P
L
G
T
G
I
R
L
N
P
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation