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Updated November 2019
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Protein Info
Short Name:
FAM185A
Full Name:
Protein FAM185A
Alias:
Type:
Mass (Da):
42301
Number AA:
392
UniProt ID:
Q8N0U4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y39
W
A
C
Q
A
R
P
Y
S
S
G
G
S
E
R
Site 2
S40
A
C
Q
A
R
P
Y
S
S
G
G
S
E
R
W
Site 3
S44
R
P
Y
S
S
G
G
S
E
R
W
P
G
S
E
Site 4
S50
G
S
E
R
W
P
G
S
E
T
E
V
P
P
P
Site 5
T52
E
R
W
P
G
S
E
T
E
V
P
P
P
G
P
Site 6
T63
P
P
G
P
G
R
R
T
L
K
E
W
T
L
Q
Site 7
T68
R
R
T
L
K
E
W
T
L
Q
V
S
P
F
G
Site 8
S72
K
E
W
T
L
Q
V
S
P
F
G
R
L
R
A
Site 9
T94
V
R
P
L
D
P
L
T
Y
P
D
G
D
R
V
Site 10
Y95
R
P
L
D
P
L
T
Y
P
D
G
D
R
V
L
Site 11
Y122
L
D
G
L
Q
V
K
Y
D
E
D
L
E
E
M
Site 12
S156
K
F
G
L
D
I
K
S
S
G
S
G
C
V
K
Site 13
S166
S
G
C
V
K
V
Q
S
I
E
G
D
N
C
K
Site 14
S181
I
E
T
E
H
G
T
S
I
L
Q
S
V
K
G
Site 15
S185
H
G
T
S
I
L
Q
S
V
K
G
Q
K
L
H
Site 16
S215
G
N
I
D
I
H
A
S
D
K
S
A
V
T
I
Site 17
S218
D
I
H
A
S
D
K
S
A
V
T
I
D
K
L
Site 18
S229
I
D
K
L
Q
G
S
S
V
T
V
S
T
E
D
Site 19
T231
K
L
Q
G
S
S
V
T
V
S
T
E
D
G
L
Site 20
S233
Q
G
S
S
V
T
V
S
T
E
D
G
L
L
K
Site 21
Y243
D
G
L
L
K
A
K
Y
L
Y
T
E
S
S
F
Site 22
Y245
L
L
K
A
K
Y
L
Y
T
E
S
S
F
L
S
Site 23
T246
L
K
A
K
Y
L
Y
T
E
S
S
F
L
S
S
Site 24
S248
A
K
Y
L
Y
T
E
S
S
F
L
S
S
A
A
Site 25
S249
K
Y
L
Y
T
E
S
S
F
L
S
S
A
A
G
Site 26
S252
Y
T
E
S
S
F
L
S
S
A
A
G
D
I
T
Site 27
T269
S
V
H
A
G
N
I
T
L
Q
S
E
M
G
N
Site 28
T278
Q
S
E
M
G
N
I
T
V
D
S
S
S
G
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation