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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABRA
Full Name:
Actin-binding Rho-activating protein
Alias:
Striated muscle activator of Rho-dependent signaling
Type:
Mass (Da):
43117
Number AA:
381
UniProt ID:
Q8N0Z2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
S
G
E
G
P
A
K
S
A
L
R
K
I
R
T
Site 2
T24
L
R
K
I
R
T
A
T
L
V
I
S
L
A
R
Site 3
S28
R
T
A
T
L
V
I
S
L
A
R
G
W
Q
Q
Site 4
S59
L
P
G
G
T
Q
D
S
P
Q
A
P
K
P
I
Site 5
T67
P
Q
A
P
K
P
I
T
P
P
T
S
H
Q
K
Site 6
T70
P
K
P
I
T
P
P
T
S
H
Q
K
A
Q
S
Site 7
S71
K
P
I
T
P
P
T
S
H
Q
K
A
Q
S
A
Site 8
S77
T
S
H
Q
K
A
Q
S
A
P
K
S
P
P
R
Site 9
S81
K
A
Q
S
A
P
K
S
P
P
R
L
P
E
G
Site 10
S94
E
G
H
G
D
G
Q
S
S
E
K
A
P
E
V
Site 11
S102
S
E
K
A
P
E
V
S
H
I
K
K
K
E
V
Site 12
S110
H
I
K
K
K
E
V
S
K
T
V
V
S
K
T
Site 13
T112
K
K
K
E
V
S
K
T
V
V
S
K
T
Y
E
Site 14
T117
S
K
T
V
V
S
K
T
Y
E
R
G
G
D
V
Site 15
Y118
K
T
V
V
S
K
T
Y
E
R
G
G
D
V
S
Site 16
S125
Y
E
R
G
G
D
V
S
H
L
S
H
R
Y
E
Site 17
S128
G
G
D
V
S
H
L
S
H
R
Y
E
R
D
A
Site 18
Y131
V
S
H
L
S
H
R
Y
E
R
D
A
G
V
L
Site 19
S153
D
I
D
R
I
L
H
S
H
G
S
P
T
R
R
Site 20
S156
R
I
L
H
S
H
G
S
P
T
R
R
R
K
C
Site 21
T158
L
H
S
H
G
S
P
T
R
R
R
K
C
A
N
Site 22
S168
R
K
C
A
N
L
V
S
E
L
T
K
G
W
R
Site 23
T183
V
M
E
Q
E
E
P
T
W
R
S
D
S
V
D
Site 24
S186
Q
E
E
P
T
W
R
S
D
S
V
D
T
E
D
Site 25
S188
E
P
T
W
R
S
D
S
V
D
T
E
D
S
G
Site 26
Y196
V
D
T
E
D
S
G
Y
G
G
E
A
E
E
R
Site 27
S222
R
I
K
R
P
L
P
S
Q
V
N
R
F
T
E
Site 28
T228
P
S
Q
V
N
R
F
T
E
K
L
N
C
K
A
Site 29
Y239
N
C
K
A
Q
Q
K
Y
S
P
V
G
N
L
K
Site 30
S240
C
K
A
Q
Q
K
Y
S
P
V
G
N
L
K
G
Site 31
S266
S
Q
K
L
N
P
F
S
E
E
F
D
Y
E
L
Site 32
Y271
P
F
S
E
E
F
D
Y
E
L
A
M
S
T
R
Site 33
S276
F
D
Y
E
L
A
M
S
T
R
L
H
K
G
D
Site 34
Y286
L
H
K
G
D
E
G
Y
G
R
P
K
E
G
T
Site 35
T293
Y
G
R
P
K
E
G
T
K
T
A
E
R
A
K
Site 36
T295
R
P
K
E
G
T
K
T
A
E
R
A
K
R
A
Site 37
Y307
K
R
A
E
E
H
I
Y
R
E
M
M
D
M
C
Site 38
T332
R
D
G
K
I
Q
V
T
F
G
D
L
F
D
R
Site 39
Y340
F
G
D
L
F
D
R
Y
V
R
I
S
D
K
V
Site 40
S344
F
D
R
Y
V
R
I
S
D
K
V
V
G
I
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation