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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPC2
Full Name:
Glypican-2
Alias:
Type:
Mass (Da):
62830
Number AA:
579
UniProt ID:
Q8N158
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
G
P
G
P
G
P
G
S
E
A
K
V
T
R
S
Site 2
T29
P
G
S
E
A
K
V
T
R
S
C
A
E
T
R
Site 3
S31
S
E
A
K
V
T
R
S
C
A
E
T
R
Q
V
Site 4
T35
V
T
R
S
C
A
E
T
R
Q
V
L
G
A
R
Site 5
Y66
L
R
V
C
P
Q
E
Y
T
C
C
S
S
E
T
Site 6
T81
E
Q
R
L
I
R
E
T
E
A
T
F
R
G
L
Site 7
T84
L
I
R
E
T
E
A
T
F
R
G
L
V
E
D
Site 8
T99
S
G
S
F
L
V
H
T
L
A
A
R
H
R
K
Site 9
T123
S
V
A
Q
H
S
L
T
Q
L
F
S
H
S
Y
Site 10
S127
H
S
L
T
Q
L
F
S
H
S
Y
G
R
L
Y
Site 11
S129
L
T
Q
L
F
S
H
S
Y
G
R
L
Y
A
Q
Site 12
Y130
T
Q
L
F
S
H
S
Y
G
R
L
Y
A
Q
H
Site 13
Y134
S
H
S
Y
G
R
L
Y
A
Q
H
A
L
I
F
Site 14
Y152
F
S
R
L
R
D
F
Y
G
E
S
G
E
G
L
Site 15
T162
S
G
E
G
L
D
D
T
L
A
D
F
W
A
Q
Site 16
Y182
F
P
L
L
H
P
Q
Y
S
F
P
P
D
Y
L
Site 17
S183
P
L
L
H
P
Q
Y
S
F
P
P
D
Y
L
L
Site 18
Y188
Q
Y
S
F
P
P
D
Y
L
L
C
L
S
R
L
Site 19
S193
P
D
Y
L
L
C
L
S
R
L
A
S
S
T
D
Site 20
S197
L
C
L
S
R
L
A
S
S
T
D
G
S
L
Q
Site 21
S198
C
L
S
R
L
A
S
S
T
D
G
S
L
Q
P
Site 22
T199
L
S
R
L
A
S
S
T
D
G
S
L
Q
P
F
Site 23
S202
L
A
S
S
T
D
G
S
L
Q
P
F
G
D
S
Site 24
S209
S
L
Q
P
F
G
D
S
P
R
R
L
R
L
Q
Site 25
S285
N
V
V
R
G
C
L
S
S
R
G
L
E
P
D
Site 26
S286
V
V
R
G
C
L
S
S
R
G
L
E
P
D
W
Site 27
S312
D
K
L
Q
G
P
F
S
F
E
L
T
A
E
S
Site 28
Y330
K
I
S
E
G
L
M
Y
L
Q
E
N
S
A
K
Site 29
S335
L
M
Y
L
Q
E
N
S
A
K
V
S
A
Q
V
Site 30
S339
Q
E
N
S
A
K
V
S
A
Q
V
F
Q
E
C
Site 31
S371
E
E
A
G
R
L
W
S
M
V
T
E
E
E
R
Site 32
T374
G
R
L
W
S
M
V
T
E
E
E
R
P
T
T
Site 33
T380
V
T
E
E
E
R
P
T
T
A
A
G
T
N
L
Site 34
T381
T
E
E
E
R
P
T
T
A
A
G
T
N
L
H
Site 35
S423
S
R
M
A
A
D
A
S
L
E
A
A
P
C
W
Site 36
Y438
T
G
A
G
R
G
R
Y
L
P
P
V
V
G
G
Site 37
S446
L
P
P
V
V
G
G
S
P
A
E
Q
V
N
N
Site 38
S461
P
E
L
K
V
D
A
S
G
P
D
V
P
T
R
Site 39
T467
A
S
G
P
D
V
P
T
R
R
R
R
L
Q
L
Site 40
T478
R
L
Q
L
R
A
A
T
A
R
M
K
T
A
A
Site 41
S500
Q
D
A
D
E
D
A
S
G
S
G
G
G
Q
Q
Site 42
Y508
G
S
G
G
G
Q
Q
Y
A
D
D
W
M
A
G
Site 43
Y528
A
R
P
P
R
P
P
Y
P
P
R
R
D
G
S
Site 44
S535
Y
P
P
R
R
D
G
S
G
G
K
G
G
G
G
Site 45
S543
G
G
K
G
G
G
G
S
A
R
Y
N
Q
G
R
Site 46
Y546
G
G
G
G
S
A
R
Y
N
Q
G
R
S
R
S
Site 47
S553
Y
N
Q
G
R
S
R
S
G
G
A
S
I
G
F
Site 48
S557
R
S
R
S
G
G
A
S
I
G
F
H
T
Q
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation