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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FTSJD2
Full Name:
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Alias:
FLJ22156; FtsJ methyltransferase domain containing 2; FtsJ methyltransferase domain-containing protein 2: FtsJ methyltransferase domain containing 2; K0082; KIAA0082; LOC23070
Type:
Transferase; EC 2.1.1.-; Methyltransferase
Mass (Da):
95321
Number AA:
835
UniProt ID:
Q8N1G2
International Prot ID:
IPI00166153
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0008168
GO:0003676
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0032259
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
R
V
A
E
L
A
L
S
L
S
S
T
S
D
D
Site 2
S28
A
E
L
A
L
S
L
S
S
T
S
D
D
E
P
Site 3
S29
E
L
A
L
S
L
S
S
T
S
D
D
E
P
P
Site 4
T30
L
A
L
S
L
S
S
T
S
D
D
E
P
P
S
Site 5
S31
A
L
S
L
S
S
T
S
D
D
E
P
P
S
S
Site 6
S37
T
S
D
D
E
P
P
S
S
V
S
H
G
A
K
Site 7
S38
S
D
D
E
P
P
S
S
V
S
H
G
A
K
A
Site 8
S46
V
S
H
G
A
K
A
S
T
T
S
L
S
G
S
Site 9
T47
S
H
G
A
K
A
S
T
T
S
L
S
G
S
D
Site 10
S49
G
A
K
A
S
T
T
S
L
S
G
S
D
S
E
Site 11
S51
K
A
S
T
T
S
L
S
G
S
D
S
E
T
E
Site 12
S53
S
T
T
S
L
S
G
S
D
S
E
T
E
G
K
Site 13
S55
T
S
L
S
G
S
D
S
E
T
E
G
K
Q
H
Site 14
T57
L
S
G
S
D
S
E
T
E
G
K
Q
H
S
S
Site 15
S63
E
T
E
G
K
Q
H
S
S
D
S
F
D
D
A
Site 16
S64
T
E
G
K
Q
H
S
S
D
S
F
D
D
A
F
Site 17
S66
G
K
Q
H
S
S
D
S
F
D
D
A
F
K
A
Site 18
S75
D
D
A
F
K
A
D
S
L
V
E
G
T
S
S
Site 19
T80
A
D
S
L
V
E
G
T
S
S
R
Y
S
M
Y
Site 20
S81
D
S
L
V
E
G
T
S
S
R
Y
S
M
Y
N
Site 21
S82
S
L
V
E
G
T
S
S
R
Y
S
M
Y
N
S
Site 22
S85
E
G
T
S
S
R
Y
S
M
Y
N
S
V
S
Q
Site 23
Y87
T
S
S
R
Y
S
M
Y
N
S
V
S
Q
K
L
Site 24
S89
S
R
Y
S
M
Y
N
S
V
S
Q
K
L
M
A
Site 25
Y109
E
G
E
G
L
G
K
Y
S
Q
G
R
K
D
I
Site 26
S110
G
E
G
L
G
K
Y
S
Q
G
R
K
D
I
V
Site 27
S121
K
D
I
V
E
A
S
S
Q
K
G
R
R
G
L
Site 28
T131
G
R
R
G
L
G
L
T
L
R
G
F
D
Q
E
Site 29
S150
W
R
D
E
P
E
P
S
A
C
E
Q
V
S
W
Site 30
T188
K
M
I
I
E
D
E
T
E
F
C
G
E
E
L
Site 31
T219
E
E
M
R
R
A
R
T
R
A
N
P
Y
E
M
Site 32
Y224
A
R
T
R
A
N
P
Y
E
M
I
R
G
V
F
Site 33
T252
F
V
F
D
R
M
F
T
N
P
R
D
S
Y
G
Site 34
S257
M
F
T
N
P
R
D
S
Y
G
K
P
L
V
K
Site 35
Y258
F
T
N
P
R
D
S
Y
G
K
P
L
V
K
D
Site 36
Y272
D
R
E
A
E
L
L
Y
F
A
D
V
C
A
G
Site 37
Y286
G
P
G
G
F
S
E
Y
V
L
W
R
K
K
W
Site 38
Y314
D
F
K
L
E
D
F
Y
S
A
S
S
E
L
F
Site 39
S315
F
K
L
E
D
F
Y
S
A
S
S
E
L
F
E
Site 40
S317
L
E
D
F
Y
S
A
S
S
E
L
F
E
P
Y
Site 41
S318
E
D
F
Y
S
A
S
S
E
L
F
E
P
Y
Y
Site 42
Y324
S
S
E
L
F
E
P
Y
Y
G
E
G
G
I
D
Site 43
Y325
S
E
L
F
E
P
Y
Y
G
E
G
G
I
D
G
Site 44
T337
I
D
G
D
G
D
I
T
R
P
E
N
I
S
A
Site 45
T353
R
N
F
V
L
D
N
T
D
R
K
G
V
H
F
Site 46
S368
L
M
A
D
G
G
F
S
V
E
G
Q
E
N
L
Site 47
S380
E
N
L
Q
E
I
L
S
K
Q
L
L
L
C
Q
Site 48
T434
V
C
L
F
K
P
I
T
S
R
P
A
N
S
E
Site 49
S440
I
T
S
R
P
A
N
S
E
R
Y
V
V
C
K
Site 50
Y443
R
P
A
N
S
E
R
Y
V
V
C
K
G
L
K
Site 51
T473
K
L
N
Q
L
R
N
T
D
S
D
V
N
L
V
Site 52
S475
N
Q
L
R
N
T
D
S
D
V
N
L
V
V
P
Site 53
Y495
G
D
H
E
F
T
D
Y
M
I
R
S
N
E
S
Site 54
S502
Y
M
I
R
S
N
E
S
H
C
S
L
Q
I
K
Site 55
S505
R
S
N
E
S
H
C
S
L
Q
I
K
A
L
A
Site 56
T521
I
H
A
F
V
Q
D
T
T
L
S
E
P
R
Q
Site 57
T522
H
A
F
V
Q
D
T
T
L
S
E
P
R
Q
A
Site 58
S550
D
Q
A
R
V
A
P
S
S
S
D
P
K
S
K
Site 59
S551
Q
A
R
V
A
P
S
S
S
D
P
K
S
K
F
Site 60
S552
A
R
V
A
P
S
S
S
D
P
K
S
K
F
F
Site 61
S556
P
S
S
S
D
P
K
S
K
F
F
E
L
I
Q
Site 62
T575
D
I
F
S
Y
K
P
T
L
L
T
S
K
T
L
Site 63
T581
P
T
L
L
T
S
K
T
L
E
K
I
R
P
V
Site 64
Y591
K
I
R
P
V
F
D
Y
R
C
M
V
S
G
S
Site 65
S598
Y
R
C
M
V
S
G
S
E
Q
K
F
L
I
G
Site 66
Y612
G
L
G
K
S
Q
I
Y
T
W
D
G
R
Q
S
Site 67
T613
L
G
K
S
Q
I
Y
T
W
D
G
R
Q
S
D
Site 68
T629
W
I
K
L
D
L
K
T
E
L
P
R
D
T
L
Site 69
T669
D
V
L
V
L
N
G
T
D
V
R
E
Q
H
F
Site 70
S691
E
K
F
V
K
A
V
S
K
P
S
R
P
D
M
Site 71
S694
V
K
A
V
S
K
P
S
R
P
D
M
N
P
I
Site 72
Y707
P
I
R
V
K
E
V
Y
R
L
E
E
M
E
K
Site 73
S728
M
K
I
I
K
G
S
S
G
T
P
K
L
S
Y
Site 74
T730
I
I
K
G
S
S
G
T
P
K
L
S
Y
T
G
Site 75
S734
S
S
G
T
P
K
L
S
Y
T
G
R
D
D
R
Site 76
Y735
S
G
T
P
K
L
S
Y
T
G
R
D
D
R
H
Site 77
T736
G
T
P
K
L
S
Y
T
G
R
D
D
R
H
F
Site 78
T759
R
T
V
N
E
P
W
T
M
G
F
S
K
S
F
Site 79
Y772
S
F
K
K
K
F
F
Y
N
K
K
T
K
D
S
Site 80
S779
Y
N
K
K
T
K
D
S
T
F
D
L
P
A
D
Site 81
T780
N
K
K
T
K
D
S
T
F
D
L
P
A
D
S
Site 82
S812
D
G
I
R
V
H
D
S
Q
K
P
Q
D
Q
D
Site 83
S822
P
Q
D
Q
D
K
L
S
K
E
D
V
L
S
F
Site 84
S828
L
S
K
E
D
V
L
S
F
I
Q
M
H
R
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation