KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
LRRC47
Full Name:
Leucine-rich repeat-containing protein 47
Alias:
KIAA1185; leucine rich repeat containing 47; LRC47; RP1-286D6.3
Type:
Mass (Da):
63473
Number AA:
583
UniProt ID:
Q8N1G4
International Prot ID:
IPI00170935
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003723
GO:0003824
PhosphoSite+
KinaseNET
Biological Process:
GO:0006412
GO:0008152
GO:0009058
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T27
R
R
R
E
L
L
L
T
G
P
G
L
E
E
R
Site 2
Y54
F
T
L
P
L
L
H
Y
L
E
V
S
G
C
G
Site 3
S62
L
E
V
S
G
C
G
S
L
R
A
P
G
P
G
Site 4
S79
Q
G
L
P
Q
L
H
S
L
V
L
R
R
N
A
Site 5
S92
N
A
L
G
P
G
L
S
P
E
L
G
P
L
P
Site 6
S133
P
G
L
P
Q
L
Q
S
L
N
L
S
G
N
R
Site 7
S137
Q
L
Q
S
L
N
L
S
G
N
R
L
R
E
L
Site 8
S157
R
C
A
P
R
L
Q
S
L
N
L
T
G
N
C
Site 9
T161
R
L
Q
S
L
N
L
T
G
N
C
L
D
S
F
Site 10
S195
D
N
C
L
R
E
L
S
P
D
I
A
H
L
A
Site 11
T206
A
H
L
A
S
L
K
T
L
D
L
S
N
N
Q
Site 12
S210
S
L
K
T
L
D
L
S
N
N
Q
L
S
E
I
Site 13
S215
D
L
S
N
N
Q
L
S
E
I
P
A
E
L
A
Site 14
S247
K
R
L
E
K
M
V
S
G
C
Q
T
R
S
I
Site 15
T251
K
M
V
S
G
C
Q
T
R
S
I
L
E
Y
L
Site 16
Y257
Q
T
R
S
I
L
E
Y
L
R
V
G
G
R
G
Site 17
S275
G
K
G
R
A
E
G
S
E
K
E
E
S
R
R
Site 18
S280
E
G
S
E
K
E
E
S
R
R
K
R
R
E
R
Site 19
T322
S
E
N
P
V
P
L
T
V
R
V
S
P
E
V
Site 20
S326
V
P
L
T
V
R
V
S
P
E
V
R
D
V
R
Site 21
Y335
E
V
R
D
V
R
P
Y
I
V
G
A
V
V
R
Site 22
T357
N
A
L
K
R
F
L
T
S
Q
T
K
L
H
E
Site 23
S358
A
L
K
R
F
L
T
S
Q
T
K
L
H
E
D
Site 24
Y389
A
V
K
G
P
L
L
Y
C
A
R
P
P
Q
D
Site 25
S431
R
K
Q
K
K
R
Q
S
V
S
G
L
H
R
Y
Site 26
S433
Q
K
K
R
Q
S
V
S
G
L
H
R
Y
L
H
Site 27
Y438
S
V
S
G
L
H
R
Y
L
H
L
L
D
G
N
Site 28
Y448
L
L
D
G
N
E
N
Y
P
C
L
V
D
A
D
Site 29
S460
D
A
D
G
D
V
I
S
F
P
P
I
T
N
S
Site 30
T465
V
I
S
F
P
P
I
T
N
S
E
K
T
K
V
Site 31
S467
S
F
P
P
I
T
N
S
E
K
T
K
V
K
K
Site 32
S477
T
K
V
K
K
T
T
S
D
L
F
L
E
V
T
Site 33
Y509
K
M
A
E
M
K
K
Y
T
L
E
N
K
E
E
Site 34
T510
M
A
E
M
K
K
Y
T
L
E
N
K
E
E
G
Site 35
S518
L
E
N
K
E
E
G
S
L
S
D
T
E
A
D
Site 36
S520
N
K
E
E
G
S
L
S
D
T
E
A
D
A
V
Site 37
T522
E
E
G
S
L
S
D
T
E
A
D
A
V
S
G
Site 38
S528
D
T
E
A
D
A
V
S
G
Q
L
P
D
P
T
Site 39
T535
S
G
Q
L
P
D
P
T
T
N
P
S
A
G
K
Site 40
T536
G
Q
L
P
D
P
T
T
N
P
S
A
G
K
D
Site 41
S539
P
D
P
T
T
N
P
S
A
G
K
D
G
P
S
Site 42
Y566
E
G
S
L
K
V
V
Y
P
S
K
A
D
L
A
Site 43
T574
P
S
K
A
D
L
A
T
A
P
P
H
V
T
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation