PhosphoNET

           
Protein Info 
   
Short Name:  VMD2L3
Full Name:  Bestrophin-3
Alias:  BEST3; Bestrophin 3; Bestrophin-4; MGC13168; MGC40411; Vitelliform macular dystrophy 2-like 3; VMDL3
Type:  Unknown function
Mass (Da):  76107
Number AA:  668
UniProt ID:  Q8N1M1
International Prot ID:  IPI00168901
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0034707  GO:0005886   Uniprot OncoNet
Molecular Function:  GO:0005509  GO:0005254  GO:0031404 PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y61LTGVQKRYFEKLSIY
Site 2Y68YFEKLSIYCDRYAEQ
Site 3Y72LSIYCDRYAEQIPVT
Site 4S111DRLMFLISSSVHGSD
Site 5S112RLMFLISSSVHGSDE
Site 6S117ISSSVHGSDEHGRLL
Site 7T127HGRLLRRTLMRYVNL
Site 8Y131LRRTLMRYVNLTSLL
Site 9Y148RSVSTAVYKRFPTMD
Site 10T153AVYKRFPTMDHVVEA
Site 11S204NEGRIRDSVDLQSLM
Site 12S209RDSVDLQSLMTEMNR
Site 13Y217LMTEMNRYRSWCSLL
Site 14T261GRQFLDPTKGYAGHD
Site 15S328AVDEMHMSLPKMKKD
Site 16Y337PKMKKDIYWDDSAAR
Site 17Y347DSAARPPYTLAAADY
Site 18T348SAARPPYTLAAADYC
Site 19S369STVQMGLSGSDFPDE
Site 20S371VQMGLSGSDFPDEEW
Site 21S390EKHGHRHSMIRRVKR
Site 22S400RRVKRFLSAHEHPSS
Site 23S406LSAHEHPSSPRRRSY
Site 24S407SAHEHPSSPRRRSYR
Site 25S412PSSPRRRSYRRQTSD
Site 26Y413SSPRRRSYRRQTSDS
Site 27T417RRSYRRQTSDSSMFL
Site 28S418RSYRRQTSDSSMFLP
Site 29S420YRRQTSDSSMFLPRD
Site 30S430FLPRDDLSPARDLLD
Site 31S440RDLLDVPSRNPPRAS
Site 32S447SRNPPRASPTWKKSC
Site 33T449NPPRASPTWKKSCFP
Site 34S453ASPTWKKSCFPEGSP
Site 35S459KSCFPEGSPTLHFSM
Site 36T461CFPEGSPTLHFSMGE
Site 37S470HFSMGELSTIRETSQ
Site 38T471FSMGELSTIRETSQT
Site 39T475ELSTIRETSQTSTLQ
Site 40S476LSTIRETSQTSTLQS
Site 41T478TIRETSQTSTLQSLT
Site 42S479IRETSQTSTLQSLTP
Site 43T480RETSQTSTLQSLTPQ
Site 44S483SQTSTLQSLTPQSSV
Site 45T485TSTLQSLTPQSSVRT
Site 46S488LQSLTPQSSVRTSPI
Site 47S489QSLTPQSSVRTSPIK
Site 48T492TPQSSVRTSPIKMPL
Site 49S493PQSSVRTSPIKMPLV
Site 50S515AEAPVPTSGGYHHDS
Site 51S522SGGYHHDSATSILSS
Site 52T524GYHHDSATSILSSEF
Site 53S525YHHDSATSILSSEFT
Site 54S529SATSILSSEFTGVQP
Site 55T532SILSSEFTGVQPSKT
Site 56T539TGVQPSKTEQQQGPM
Site 57S548QQQGPMGSILSPSEK
Site 58S551GPMGSILSPSEKETP
Site 59S553MGSILSPSEKETPPG
Site 60T557LSPSEKETPPGGPSP
Site 61S563ETPPGGPSPQTVSAS
Site 62T566PGGPSPQTVSASAEE
Site 63S591DTFLKRWSLPGFLGS
Site 64S598SLPGFLGSSHTSLGN
Site 65T601GFLGSSHTSLGNLSP
Site 66S602FLGSSHTSLGNLSPD
Site 67S607HTSLGNLSPDPMSSQ
Site 68S612NLSPDPMSSQPALLI
Site 69S613LSPDPMSSQPALLID
Site 70T621QPALLIDTETSSEIS
Site 71S624LLIDTETSSEISGIN
Site 72Y644RVSSDMLYLMENLDT
Site 73T651YLMENLDTKETDIIE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation