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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PROM2
Full Name:
Prominin-2
Alias:
PROM-2; Prominin 2; Prominin-like protein 2; Prominin-related
Type:
Membrane protein, integral; Cell surface
Mass (Da):
91865
Number AA:
834
UniProt ID:
Q8N271
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005929
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T40
L
G
P
A
E
H
L
T
F
T
P
A
A
R
A
Site 2
T42
P
A
E
H
L
T
F
T
P
A
A
R
A
R
W
Site 3
S62
R
A
P
G
L
L
D
S
L
Y
G
T
V
R
R
Site 4
T142
R
C
G
G
R
V
K
T
E
H
K
A
L
A
C
Site 5
S223
S
L
P
Q
E
Q
V
S
E
E
L
D
G
V
G
Site 6
T239
S
I
G
S
A
I
H
T
Q
L
R
S
S
V
Y
Site 7
S324
L
E
L
G
A
D
F
S
Q
V
P
S
V
D
H
Site 8
S328
A
D
F
S
Q
V
P
S
V
D
H
V
L
H
Q
Site 9
S345
G
V
P
E
A
N
F
S
S
M
V
Q
E
E
N
Site 10
S346
V
P
E
A
N
F
S
S
M
V
Q
E
E
N
S
Site 11
T354
M
V
Q
E
E
N
S
T
F
N
A
L
P
A
L
Site 12
S368
L
A
A
M
Q
T
S
S
V
V
Q
E
L
K
K
Site 13
T386
Q
Q
P
E
G
V
R
T
L
A
E
G
F
P
G
Site 14
S410
A
L
Q
E
V
E
E
S
S
R
P
Y
L
Q
E
Site 15
Y414
V
E
E
S
S
R
P
Y
L
Q
E
V
Q
R
Y
Site 16
Y421
Y
L
Q
E
V
Q
R
Y
E
T
Y
R
W
I
V
Site 17
T423
Q
E
V
Q
R
Y
E
T
Y
R
W
I
V
G
C
Site 18
Y424
E
V
Q
R
Y
E
T
Y
R
W
I
V
G
C
V
Site 19
S455
N
L
G
I
W
G
L
S
A
R
D
D
P
S
H
Site 20
S461
L
S
A
R
D
D
P
S
H
P
E
A
K
G
E
Site 21
T521
E
L
F
E
F
A
D
T
P
G
N
L
P
P
S
Site 22
S528
T
P
G
N
L
P
P
S
M
N
L
S
Q
L
L
Site 23
S532
L
P
P
S
M
N
L
S
Q
L
L
G
L
R
K
Site 24
S542
L
G
L
R
K
N
I
S
I
H
Q
A
Y
Q
Q
Site 25
S565
T
V
L
Q
L
N
D
S
Y
D
L
E
E
H
L
Site 26
Y566
V
L
Q
L
N
D
S
Y
D
L
E
E
H
L
D
Site 27
Y577
E
H
L
D
I
N
Q
Y
T
N
K
L
R
Q
E
Site 28
S587
K
L
R
Q
E
L
Q
S
L
K
V
D
T
Q
S
Site 29
T592
L
Q
S
L
K
V
D
T
Q
S
L
D
L
L
S
Site 30
S594
S
L
K
V
D
T
Q
S
L
D
L
L
S
S
A
Site 31
S600
Q
S
L
D
L
L
S
S
A
A
R
R
D
L
E
Site 32
S611
R
D
L
E
A
L
Q
S
S
G
L
Q
R
I
H
Site 33
Y619
S
G
L
Q
R
I
H
Y
P
D
F
L
V
Q
I
Site 34
T633
I
Q
R
P
V
V
K
T
S
M
E
Q
L
A
Q
Site 35
S652
L
A
Q
A
Q
D
N
S
V
L
G
Q
R
L
Q
Site 36
S693
S
V
R
A
L
E
S
S
A
P
N
L
Q
L
E
Site 37
S727
A
R
I
L
R
N
V
S
E
C
F
L
A
R
E
Site 38
Y741
E
M
G
Y
F
S
Q
Y
V
A
W
V
R
E
E
Site 39
T750
A
W
V
R
E
E
V
T
Q
R
I
A
T
C
Q
Site 40
T755
E
V
T
Q
R
I
A
T
C
Q
P
L
S
G
A
Site 41
S760
I
A
T
C
Q
P
L
S
G
A
L
D
N
S
R
Site 42
T802
S
I
I
F
A
V
K
T
S
K
Y
F
R
P
I
Site 43
S803
I
I
F
A
V
K
T
S
K
Y
F
R
P
I
R
Site 44
Y805
F
A
V
K
T
S
K
Y
F
R
P
I
R
K
R
Site 45
S814
R
P
I
R
K
R
L
S
S
T
S
S
E
E
T
Site 46
S815
P
I
R
K
R
L
S
S
T
S
S
E
E
T
Q
Site 47
T816
I
R
K
R
L
S
S
T
S
S
E
E
T
Q
L
Site 48
S817
R
K
R
L
S
S
T
S
S
E
E
T
Q
L
F
Site 49
S818
K
R
L
S
S
T
S
S
E
E
T
Q
L
F
H
Site 50
T821
S
S
T
S
S
E
E
T
Q
L
F
H
I
P
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation