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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANKRD35
Full Name:
Ankyrin repeat domain-containing protein 35
Alias:
Type:
Mass (Da):
109966
Number AA:
1001
UniProt ID:
Q8N283
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
R
I
F
S
C
S
S
T
Q
V
A
V
E
R
W
Site 2
S44
A
A
L
A
S
R
K
S
A
R
P
T
K
L
D
Site 3
T48
S
R
K
S
A
R
P
T
K
L
D
S
N
G
Q
Site 4
S52
A
R
P
T
K
L
D
S
N
G
Q
S
P
F
H
Site 5
S56
K
L
D
S
N
G
Q
S
P
F
H
L
A
A
S
Site 6
S82
A
N
G
A
D
I
N
S
K
N
E
D
G
S
T
Site 7
S88
N
S
K
N
E
D
G
S
T
A
L
H
L
A
T
Site 8
T89
S
K
N
E
D
G
S
T
A
L
H
L
A
T
I
Site 9
S122
A
V
D
A
E
N
R
S
P
L
H
W
A
A
S
Site 10
S188
V
T
D
K
N
D
K
S
A
L
I
L
A
C
E
Site 11
T218
D
A
G
A
V
D
S
T
G
H
D
A
L
H
Y
Site 12
Y225
T
G
H
D
A
L
H
Y
A
L
H
T
Q
D
K
Site 13
S243
R
H
L
Q
Q
A
L
S
R
R
R
R
G
G
Q
Site 14
S260
V
Q
H
P
D
L
A
S
Q
A
S
P
S
E
P
Site 15
S263
P
D
L
A
S
Q
A
S
P
S
E
P
Q
A
G
Site 16
S265
L
A
S
Q
A
S
P
S
E
P
Q
A
G
S
P
Site 17
S271
P
S
E
P
Q
A
G
S
P
P
K
S
S
W
R
Site 18
S275
Q
A
G
S
P
P
K
S
S
W
R
A
E
P
E
Site 19
S276
A
G
S
P
P
K
S
S
W
R
A
E
P
E
E
Site 20
Y302
S
E
E
W
R
W
K
Y
E
E
E
R
R
K
V
Site 21
T325
Q
K
T
E
E
C
K
T
Q
A
A
A
Y
L
D
Site 22
S349
Q
E
L
G
V
L
L
S
W
E
P
R
A
S
G
Site 23
S355
L
S
W
E
P
R
A
S
G
K
Q
G
S
S
L
Site 24
S360
R
A
S
G
K
Q
G
S
S
L
R
P
G
G
D
Site 25
S361
A
S
G
K
Q
G
S
S
L
R
P
G
G
D
G
Site 26
T394
K
Q
Q
Q
A
A
A
T
V
N
P
V
L
A
P
Site 27
S407
A
P
K
K
A
E
D
S
A
P
G
K
I
Q
Y
Site 28
Y414
S
A
P
G
K
I
Q
Y
E
V
H
G
R
S
Q
Site 29
S430
E
E
Q
G
P
P
Q
S
P
A
S
E
T
I
R
Site 30
S433
G
P
P
Q
S
P
A
S
E
T
I
R
K
A
T
Site 31
T435
P
Q
S
P
A
S
E
T
I
R
K
A
T
G
Q
Site 32
T440
S
E
T
I
R
K
A
T
G
Q
Q
L
T
T
N
Site 33
T451
L
T
T
N
G
A
Q
T
F
G
P
D
H
A
D
Site 34
S468
P
A
G
Q
K
E
S
S
Q
V
L
G
V
E
P
Site 35
S577
A
L
K
A
A
P
G
S
I
K
Q
D
E
E
K
Site 36
S618
G
Q
L
E
K
E
M
S
V
L
R
L
S
N
S
Site 37
S623
E
M
S
V
L
R
L
S
N
S
N
L
L
E
E
Site 38
S625
S
V
L
R
L
S
N
S
N
L
L
E
E
L
G
Site 39
S647
R
L
Q
R
E
L
Q
S
L
S
Q
R
L
Q
R
Site 40
S649
Q
R
E
L
Q
S
L
S
Q
R
L
Q
R
E
F
Site 41
S672
Q
L
Q
Q
L
R
Q
S
V
G
L
L
T
N
E
Site 42
T687
L
A
M
E
K
E
A
T
E
K
L
R
K
L
L
Site 43
S696
K
L
R
K
L
L
A
S
Q
S
S
G
L
R
G
Site 44
S698
R
K
L
L
A
S
Q
S
S
G
L
R
G
L
W
Site 45
S699
K
L
L
A
S
Q
S
S
G
L
R
G
L
W
D
Site 46
S717
A
D
L
V
G
E
R
S
A
Q
S
K
A
A
E
Site 47
S725
A
Q
S
K
A
A
E
S
L
E
E
L
R
A
C
Site 48
S734
E
E
L
R
A
C
I
S
T
L
V
D
R
H
R
Site 49
T735
E
L
R
A
C
I
S
T
L
V
D
R
H
R
E
Site 50
S760
E
N
Q
Q
L
R
G
S
L
S
P
C
R
E
P
Site 51
S762
Q
Q
L
R
G
S
L
S
P
C
R
E
P
G
T
Site 52
T769
S
P
C
R
E
P
G
T
S
L
K
A
P
A
S
Site 53
S770
P
C
R
E
P
G
T
S
L
K
A
P
A
S
P
Site 54
T799
E
L
R
A
V
Q
A
T
M
S
G
K
S
Q
E
Site 55
S804
Q
A
T
M
S
G
K
S
Q
E
I
G
K
L
K
Site 56
Y815
G
K
L
K
Q
L
L
Y
Q
A
T
E
E
V
A
Site 57
S831
L
R
A
R
E
A
A
S
L
R
Q
H
E
K
T
Site 58
T838
S
L
R
Q
H
E
K
T
R
G
S
L
V
A
Q
Site 59
S841
Q
H
E
K
T
R
G
S
L
V
A
Q
A
Q
A
Site 60
T862
A
L
L
E
K
Y
N
T
A
C
R
E
V
G
R
Site 61
S881
V
A
E
E
R
R
R
S
G
D
L
A
A
Q
A
Site 62
S896
A
E
Q
E
R
Q
A
S
E
M
R
G
R
S
E
Site 63
S902
A
S
E
M
R
G
R
S
E
Q
F
E
K
T
A
Site 64
S961
L
A
L
Q
L
Q
D
S
Q
K
N
H
E
E
I
Site 65
T971
N
H
E
E
I
I
S
T
Y
R
N
H
L
L
N
Site 66
Y983
L
L
N
A
A
R
G
Y
M
E
H
E
V
Y
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation