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Updated November 2019
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Protein Info
Short Name:
PELI3
Full Name:
Protein pellino homolog 3
Alias:
Type:
Mass (Da):
50755
Number AA:
469
UniProt ID:
Q8N2H9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
E
G
N
P
E
V
G
S
P
R
T
S
D
L
Q
Site 2
S15
E
V
G
S
P
R
T
S
D
L
Q
H
R
G
N
Site 3
S25
Q
H
R
G
N
K
G
S
C
V
L
S
S
P
G
Site 4
S29
N
K
G
S
C
V
L
S
S
P
G
E
D
A
Q
Site 5
S30
K
G
S
C
V
L
S
S
P
G
E
D
A
Q
P
Site 6
S74
V
T
G
P
R
A
H
S
C
Y
N
G
C
L
A
Site 7
Y76
G
P
R
A
H
S
C
Y
N
G
C
L
A
S
G
Site 8
S90
G
D
K
G
R
R
R
S
R
L
A
L
S
R
R
Site 9
S95
R
R
S
R
L
A
L
S
R
R
S
H
A
N
G
Site 10
S98
R
L
A
L
S
R
R
S
H
A
N
G
V
K
P
Site 11
S117
H
I
S
T
P
L
V
S
K
A
L
S
N
R
G
Site 12
S121
P
L
V
S
K
A
L
S
N
R
G
Q
H
S
I
Site 13
S127
L
S
N
R
G
Q
H
S
I
S
Y
T
L
S
R
Site 14
S129
N
R
G
Q
H
S
I
S
Y
T
L
S
R
S
H
Site 15
Y130
R
G
Q
H
S
I
S
Y
T
L
S
R
S
H
S
Site 16
T131
G
Q
H
S
I
S
Y
T
L
S
R
S
H
S
V
Site 17
S133
H
S
I
S
Y
T
L
S
R
S
H
S
V
I
V
Site 18
S135
I
S
Y
T
L
S
R
S
H
S
V
I
V
E
Y
Site 19
S137
Y
T
L
S
R
S
H
S
V
I
V
E
Y
T
H
Site 20
Y142
S
H
S
V
I
V
E
Y
T
H
D
S
D
T
D
Site 21
S169
D
F
V
V
T
D
T
S
P
G
G
G
A
A
E
Site 22
S179
G
G
A
A
E
G
P
S
A
Q
S
T
I
S
R
Site 23
T183
E
G
P
S
A
Q
S
T
I
S
R
Y
A
C
R
Site 24
S185
P
S
A
Q
S
T
I
S
R
Y
A
C
R
I
L
Site 25
Y187
A
Q
S
T
I
S
R
Y
A
C
R
I
L
C
D
Site 26
Y199
L
C
D
R
R
P
P
Y
T
A
R
I
Y
A
A
Site 27
T200
C
D
R
R
P
P
Y
T
A
R
I
Y
A
A
G
Site 28
Y204
P
P
Y
T
A
R
I
Y
A
A
G
F
D
A
S
Site 29
S212
A
A
G
F
D
A
S
S
N
I
F
L
G
E
R
Site 30
T225
E
R
A
A
K
W
R
T
P
D
G
L
M
D
G
Site 31
S251
A
G
G
F
S
E
D
S
A
P
G
V
W
R
E
Site 32
Y266
I
S
V
C
G
N
V
Y
T
L
R
D
S
R
S
Site 33
T267
S
V
C
G
N
V
Y
T
L
R
D
S
R
S
A
Site 34
S271
N
V
Y
T
L
R
D
S
R
S
A
Q
Q
R
G
Site 35
S273
Y
T
L
R
D
S
R
S
A
Q
Q
R
G
K
L
Site 36
S285
G
K
L
V
E
N
E
S
N
V
L
Q
D
G
S
Site 37
T314
A
G
L
L
R
A
P
T
L
K
Q
L
E
A
Q
Site 38
S343
L
S
T
L
A
F
P
S
P
A
R
G
R
T
A
Site 39
T349
P
S
P
A
R
G
R
T
A
P
D
K
Q
Q
P
Site 40
S412
C
L
D
P
G
P
P
S
H
A
F
A
P
C
G
Site 41
Y429
C
S
E
K
T
A
R
Y
W
A
Q
T
P
L
P
Site 42
T433
T
A
R
Y
W
A
Q
T
P
L
P
H
G
T
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation