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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SFRS16
Full Name:
Splicing factor, arginine/serine-rich 16
Alias:
CLASP; Clk4 associating SR-related protein; SFR16; Splicing factor, arginine/serine-rich 16; Suppressor of white apricot 2; Suppressor of white-apricot 2; Suppressor of white-apricot homologue 2; SWAP2
Type:
Uncharacterized protein
Mass (Da):
77161
Number AA:
674
UniProt ID:
Q8N2M8
International Prot ID:
IPI00013107
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006396
GO:0006397
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y19
L
R
G
M
M
V
D
Y
K
K
R
A
E
R
R
Site 2
Y29
R
A
E
R
R
R
E
Y
Y
E
K
I
K
K
D
Site 3
Y30
A
E
R
R
R
E
Y
Y
E
K
I
K
K
D
P
Site 4
Y92
H
L
D
H
I
P
D
Y
T
P
P
L
L
T
T
Site 5
T99
Y
T
P
P
L
L
T
T
I
S
P
E
Q
E
S
Site 6
S101
P
P
L
L
T
T
I
S
P
E
Q
E
S
D
E
Site 7
S106
T
I
S
P
E
Q
E
S
D
E
R
K
C
N
Y
Site 8
Y113
S
D
E
R
K
C
N
Y
E
R
Y
R
G
L
V
Site 9
Y134
I
S
E
E
Q
C
L
Y
Q
I
Y
I
D
E
L
Site 10
Y137
E
Q
C
L
Y
Q
I
Y
I
D
E
L
Y
G
G
Site 11
Y142
Q
I
Y
I
D
E
L
Y
G
G
L
Q
R
P
S
Site 12
S149
Y
G
G
L
Q
R
P
S
E
D
E
K
K
K
L
Site 13
S162
K
L
A
E
K
K
A
S
I
G
Y
T
Y
E
D
Site 14
T166
K
K
A
S
I
G
Y
T
Y
E
D
S
T
V
A
Site 15
S170
I
G
Y
T
Y
E
D
S
T
V
A
K
V
E
K
Site 16
T171
G
Y
T
Y
E
D
S
T
V
A
K
V
E
K
A
Site 17
S187
E
K
P
E
E
E
E
S
A
A
E
E
E
S
N
Site 18
S195
A
A
E
E
E
S
N
S
D
E
D
E
V
I
P
Site 19
Y228
L
N
K
Q
A
T
T
Y
G
M
A
D
G
D
F
Site 20
Y262
L
E
E
E
K
A
M
Y
S
G
R
R
S
R
R
Site 21
S263
E
E
E
K
A
M
Y
S
G
R
R
S
R
R
Q
Site 22
S267
A
M
Y
S
G
R
R
S
R
R
Q
R
R
E
F
Site 23
S285
R
L
R
G
R
K
I
S
P
P
S
Y
A
R
R
Site 24
S288
G
R
K
I
S
P
P
S
Y
A
R
R
D
S
P
Site 25
Y289
R
K
I
S
P
P
S
Y
A
R
R
D
S
P
T
Site 26
S294
P
S
Y
A
R
R
D
S
P
T
Y
D
P
Y
K
Site 27
T296
Y
A
R
R
D
S
P
T
Y
D
P
Y
K
R
S
Site 28
Y297
A
R
R
D
S
P
T
Y
D
P
Y
K
R
S
P
Site 29
Y300
D
S
P
T
Y
D
P
Y
K
R
S
P
S
E
S
Site 30
S303
T
Y
D
P
Y
K
R
S
P
S
E
S
S
S
E
Site 31
S305
D
P
Y
K
R
S
P
S
E
S
S
S
E
S
R
Site 32
S307
Y
K
R
S
P
S
E
S
S
S
E
S
R
S
R
Site 33
S308
K
R
S
P
S
E
S
S
S
E
S
R
S
R
S
Site 34
S309
R
S
P
S
E
S
S
S
E
S
R
S
R
S
R
Site 35
S311
P
S
E
S
S
S
E
S
R
S
R
S
R
S
P
Site 36
S313
E
S
S
S
E
S
R
S
R
S
R
S
P
T
P
Site 37
S315
S
S
E
S
R
S
R
S
R
S
P
T
P
G
R
Site 38
S317
E
S
R
S
R
S
R
S
P
T
P
G
R
E
E
Site 39
T319
R
S
R
S
R
S
P
T
P
G
R
E
E
K
I
Site 40
T327
P
G
R
E
E
K
I
T
F
I
T
S
F
G
G
Site 41
T330
E
E
K
I
T
F
I
T
S
F
G
G
S
D
E
Site 42
S331
E
K
I
T
F
I
T
S
F
G
G
S
D
E
E
Site 43
S335
F
I
T
S
F
G
G
S
D
E
E
A
A
A
A
Site 44
T353
A
A
A
S
G
V
T
T
G
K
P
P
A
P
P
Site 45
S372
P
A
P
G
R
N
A
S
A
R
R
R
S
S
S
Site 46
S377
N
A
S
A
R
R
R
S
S
S
S
S
S
S
S
Site 47
S378
A
S
A
R
R
R
S
S
S
S
S
S
S
S
S
Site 48
S379
S
A
R
R
R
S
S
S
S
S
S
S
S
S
A
Site 49
S380
A
R
R
R
S
S
S
S
S
S
S
S
S
A
S
Site 50
S381
R
R
R
S
S
S
S
S
S
S
S
S
A
S
R
Site 51
S382
R
R
S
S
S
S
S
S
S
S
S
A
S
R
T
Site 52
S383
R
S
S
S
S
S
S
S
S
S
A
S
R
T
S
Site 53
S384
S
S
S
S
S
S
S
S
S
A
S
R
T
S
S
Site 54
S385
S
S
S
S
S
S
S
S
A
S
R
T
S
S
S
Site 55
S387
S
S
S
S
S
S
A
S
R
T
S
S
S
R
S
Site 56
T389
S
S
S
S
A
S
R
T
S
S
S
R
S
S
S
Site 57
S390
S
S
S
A
S
R
T
S
S
S
R
S
S
S
R
Site 58
S391
S
S
A
S
R
T
S
S
S
R
S
S
S
R
S
Site 59
S392
S
A
S
R
T
S
S
S
R
S
S
S
R
S
S
Site 60
S394
S
R
T
S
S
S
R
S
S
S
R
S
S
S
R
Site 61
S395
R
T
S
S
S
R
S
S
S
R
S
S
S
R
S
Site 62
S396
T
S
S
S
R
S
S
S
R
S
S
S
R
S
R
Site 63
S398
S
S
R
S
S
S
R
S
S
S
R
S
R
R
G
Site 64
S399
S
R
S
S
S
R
S
S
S
R
S
R
R
G
G
Site 65
S400
R
S
S
S
R
S
S
S
R
S
R
R
G
G
G
Site 66
S402
S
S
R
S
S
S
R
S
R
R
G
G
G
Y
Y
Site 67
Y408
R
S
R
R
G
G
G
Y
Y
R
S
G
R
H
A
Site 68
Y409
S
R
R
G
G
G
Y
Y
R
S
G
R
H
A
R
Site 69
S411
R
G
G
G
Y
Y
R
S
G
R
H
A
R
S
R
Site 70
S417
R
S
G
R
H
A
R
S
R
S
R
S
W
S
R
Site 71
S419
G
R
H
A
R
S
R
S
R
S
W
S
R
S
R
Site 72
S421
H
A
R
S
R
S
R
S
W
S
R
S
R
S
R
Site 73
S423
R
S
R
S
R
S
W
S
R
S
R
S
R
S
R
Site 74
S425
R
S
R
S
W
S
R
S
R
S
R
S
R
R
Y
Site 75
S427
R
S
W
S
R
S
R
S
R
S
R
R
Y
S
R
Site 76
S429
W
S
R
S
R
S
R
S
R
R
Y
S
R
S
R
Site 77
Y432
S
R
S
R
S
R
R
Y
S
R
S
R
S
R
G
Site 78
S433
R
S
R
S
R
R
Y
S
R
S
R
S
R
G
R
Site 79
S435
R
S
R
R
Y
S
R
S
R
S
R
G
R
R
H
Site 80
S437
R
R
Y
S
R
S
R
S
R
G
R
R
H
S
G
Site 81
S443
R
S
R
G
R
R
H
S
G
G
G
S
R
D
G
Site 82
S447
R
R
H
S
G
G
G
S
R
D
G
H
R
Y
S
Site 83
Y453
G
S
R
D
G
H
R
Y
S
R
S
P
A
R
R
Site 84
S454
S
R
D
G
H
R
Y
S
R
S
P
A
R
R
G
Site 85
S456
D
G
H
R
Y
S
R
S
P
A
R
R
G
G
Y
Site 86
Y463
S
P
A
R
R
G
G
Y
G
P
R
R
R
S
R
Site 87
S469
G
Y
G
P
R
R
R
S
R
S
R
S
H
S
G
Site 88
S471
G
P
R
R
R
S
R
S
R
S
H
S
G
D
R
Site 89
S473
R
R
R
S
R
S
R
S
H
S
G
D
R
Y
R
Site 90
S475
R
S
R
S
R
S
H
S
G
D
R
Y
R
R
G
Site 91
Y479
R
S
H
S
G
D
R
Y
R
R
G
G
R
G
L
Site 92
S490
G
R
G
L
R
H
H
S
S
S
R
S
R
S
S
Site 93
S491
R
G
L
R
H
H
S
S
S
R
S
R
S
S
W
Site 94
S492
G
L
R
H
H
S
S
S
R
S
R
S
S
W
S
Site 95
S494
R
H
H
S
S
S
R
S
R
S
S
W
S
L
S
Site 96
S496
H
S
S
S
R
S
R
S
S
W
S
L
S
P
S
Site 97
S497
S
S
S
R
S
R
S
S
W
S
L
S
P
S
R
Site 98
S499
S
R
S
R
S
S
W
S
L
S
P
S
R
S
R
Site 99
S501
S
R
S
S
W
S
L
S
P
S
R
S
R
S
L
Site 100
S503
S
S
W
S
L
S
P
S
R
S
R
S
L
T
R
Site 101
S505
W
S
L
S
P
S
R
S
R
S
L
T
R
S
R
Site 102
S507
L
S
P
S
R
S
R
S
L
T
R
S
R
S
H
Site 103
T509
P
S
R
S
R
S
L
T
R
S
R
S
H
S
P
Site 104
S511
R
S
R
S
L
T
R
S
R
S
H
S
P
S
P
Site 105
S513
R
S
L
T
R
S
R
S
H
S
P
S
P
S
Q
Site 106
S515
L
T
R
S
R
S
H
S
P
S
P
S
Q
S
R
Site 107
S517
R
S
R
S
H
S
P
S
P
S
Q
S
R
S
R
Site 108
S519
R
S
H
S
P
S
P
S
Q
S
R
S
R
S
R
Site 109
S521
H
S
P
S
P
S
Q
S
R
S
R
S
R
S
R
Site 110
S523
P
S
P
S
Q
S
R
S
R
S
R
S
R
S
Q
Site 111
S525
P
S
Q
S
R
S
R
S
R
S
R
S
Q
S
P
Site 112
S527
Q
S
R
S
R
S
R
S
R
S
Q
S
P
S
P
Site 113
S529
R
S
R
S
R
S
R
S
Q
S
P
S
P
S
P
Site 114
S531
R
S
R
S
R
S
Q
S
P
S
P
S
P
A
R
Site 115
S533
R
S
R
S
Q
S
P
S
P
S
P
A
R
E
K
Site 116
S535
R
S
Q
S
P
S
P
S
P
A
R
E
K
L
T
Site 117
S547
K
L
T
R
P
A
A
S
P
A
V
G
E
K
L
Site 118
T557
V
G
E
K
L
K
K
T
E
P
A
A
G
K
E
Site 119
T573
G
A
A
K
P
K
L
T
P
Q
E
K
L
K
L
Site 120
Y641
R
E
E
W
E
R
Q
Y
S
R
Q
S
R
S
P
Site 121
S642
E
E
W
E
R
Q
Y
S
R
Q
S
R
S
P
S
Site 122
S645
E
R
Q
Y
S
R
Q
S
R
S
P
S
P
R
Y
Site 123
S647
Q
Y
S
R
Q
S
R
S
P
S
P
R
Y
S
R
Site 124
S649
S
R
Q
S
R
S
P
S
P
R
Y
S
R
E
Y
Site 125
Y652
S
R
S
P
S
P
R
Y
S
R
E
Y
S
S
S
Site 126
S653
R
S
P
S
P
R
Y
S
R
E
Y
S
S
S
R
Site 127
Y656
S
P
R
Y
S
R
E
Y
S
S
S
R
R
R
S
Site 128
S657
P
R
Y
S
R
E
Y
S
S
S
R
R
R
S
R
Site 129
S658
R
Y
S
R
E
Y
S
S
S
R
R
R
S
R
S
Site 130
S659
Y
S
R
E
Y
S
S
S
R
R
R
S
R
S
R
Site 131
S663
Y
S
S
S
R
R
R
S
R
S
R
S
R
S
P
Site 132
S665
S
S
R
R
R
S
R
S
R
S
R
S
P
H
Y
Site 133
S667
R
R
R
S
R
S
R
S
R
S
P
H
Y
R
H
Site 134
S669
R
S
R
S
R
S
R
S
P
H
Y
R
H
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation