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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AGGF1
Full Name:
Angiogenic factor with G patch and FHA domains 1
Alias:
Angiogenic factor VG5Q; FLJ10283; GPATC7; GPATCH7; HSU84971; VG5Q
Type:
Angiogenesis protein, secreted
Mass (Da):
80977
Number AA:
714
UniProt ID:
Q8N302
International Prot ID:
IPI00018027
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
GO:0048471
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0043499
GO:0003676
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006396
GO:0001525
GO:0007155
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
A
S
E
A
P
S
P
P
R
Site 2
S7
_
M
A
S
E
A
P
S
P
P
R
S
P
P
P
Site 3
S11
E
A
P
S
P
P
R
S
P
P
P
P
T
S
P
Site 4
T16
P
R
S
P
P
P
P
T
S
P
E
P
E
L
A
Site 5
S17
R
S
P
P
P
P
T
S
P
E
P
E
L
A
Q
Site 6
Y57
L
H
H
T
E
R
L
Y
Q
N
A
E
S
N
N
Site 7
T69
S
N
N
Q
E
L
R
T
Q
V
E
E
L
S
K
Site 8
S89
R
N
E
D
N
K
K
S
D
V
E
V
Q
T
E
Site 9
Y106
A
P
W
S
I
S
D
Y
F
Y
Q
T
Y
Y
N
Site 10
Y108
W
S
I
S
D
Y
F
Y
Q
T
Y
Y
N
D
V
Site 11
Y111
S
D
Y
F
Y
Q
T
Y
Y
N
D
V
S
L
P
Site 12
Y112
D
Y
F
Y
Q
T
Y
Y
N
D
V
S
L
P
N
Site 13
S116
Q
T
Y
Y
N
D
V
S
L
P
N
K
V
T
E
Site 14
S125
P
N
K
V
T
E
L
S
D
Q
Q
D
Q
A
I
Site 15
S139
I
E
T
S
I
L
N
S
K
D
H
L
Q
V
E
Site 16
Y150
L
Q
V
E
N
D
A
Y
P
G
T
D
R
T
E
Site 17
T153
E
N
D
A
Y
P
G
T
D
R
T
E
N
V
K
Site 18
T156
A
Y
P
G
T
D
R
T
E
N
V
K
Y
R
Q
Site 19
Y161
D
R
T
E
N
V
K
Y
R
Q
V
D
H
F
A
Site 20
S169
R
Q
V
D
H
F
A
S
N
S
Q
E
P
A
S
Site 21
S171
V
D
H
F
A
S
N
S
Q
E
P
A
S
A
L
Site 22
S176
S
N
S
Q
E
P
A
S
A
L
A
T
E
D
T
Site 23
T180
E
P
A
S
A
L
A
T
E
D
T
S
L
E
G
Site 24
T183
S
A
L
A
T
E
D
T
S
L
E
G
S
S
L
Site 25
S184
A
L
A
T
E
D
T
S
L
E
G
S
S
L
A
Site 26
S188
E
D
T
S
L
E
G
S
S
L
A
E
S
L
R
Site 27
S189
D
T
S
L
E
G
S
S
L
A
E
S
L
R
A
Site 28
S193
E
G
S
S
L
A
E
S
L
R
A
A
A
E
A
Site 29
S203
A
A
A
E
A
A
V
S
Q
T
G
F
S
Y
D
Site 30
Y209
V
S
Q
T
G
F
S
Y
D
E
N
T
G
L
Y
Site 31
T213
G
F
S
Y
D
E
N
T
G
L
Y
F
D
H
S
Site 32
Y216
Y
D
E
N
T
G
L
Y
F
D
H
S
T
G
F
Site 33
Y224
F
D
H
S
T
G
F
Y
Y
D
S
E
N
Q
L
Site 34
Y225
D
H
S
T
G
F
Y
Y
D
S
E
N
Q
L
Y
Site 35
Y232
Y
D
S
E
N
Q
L
Y
Y
D
P
S
T
G
I
Site 36
Y233
D
S
E
N
Q
L
Y
Y
D
P
S
T
G
I
Y
Site 37
Y240
Y
D
P
S
T
G
I
Y
Y
Y
C
D
V
E
S
Site 38
Y241
D
P
S
T
G
I
Y
Y
Y
C
D
V
E
S
G
Site 39
Y242
P
S
T
G
I
Y
Y
Y
C
D
V
E
S
G
R
Site 40
Y250
C
D
V
E
S
G
R
Y
Q
F
H
S
R
V
D
Site 41
S254
S
G
R
Y
Q
F
H
S
R
V
D
L
Q
P
Y
Site 42
Y261
S
R
V
D
L
Q
P
Y
P
T
S
S
T
K
Q
Site 43
T263
V
D
L
Q
P
Y
P
T
S
S
T
K
Q
S
K
Site 44
S264
D
L
Q
P
Y
P
T
S
S
T
K
Q
S
K
D
Site 45
S265
L
Q
P
Y
P
T
S
S
T
K
Q
S
K
D
K
Site 46
S269
P
T
S
S
T
K
Q
S
K
D
K
K
L
K
K
Site 47
S283
K
K
R
K
D
P
D
S
S
A
T
N
E
E
K
Site 48
S284
K
R
K
D
P
D
S
S
A
T
N
E
E
K
D
Site 49
S301
S
E
D
Q
K
A
F
S
V
E
H
T
S
C
N
Site 50
T305
K
A
F
S
V
E
H
T
S
C
N
E
E
E
N
Site 51
S306
A
F
S
V
E
H
T
S
C
N
E
E
E
N
F
Site 52
S329
I
G
I
H
H
K
N
S
P
P
K
V
T
V
P
Site 53
T334
K
N
S
P
P
K
V
T
V
P
T
S
G
N
T
Site 54
S338
P
K
V
T
V
P
T
S
G
N
T
I
E
S
P
Site 55
S344
T
S
G
N
T
I
E
S
P
L
H
E
N
I
S
Site 56
S351
S
P
L
H
E
N
I
S
N
S
T
S
F
K
D
Site 57
S353
L
H
E
N
I
S
N
S
T
S
F
K
D
E
K
Site 58
S355
E
N
I
S
N
S
T
S
F
K
D
E
K
I
M
Site 59
S366
E
K
I
M
E
T
D
S
E
P
E
E
G
E
I
Site 60
T374
E
P
E
E
G
E
I
T
D
S
Q
T
E
D
S
Site 61
S376
E
E
G
E
I
T
D
S
Q
T
E
D
S
Y
D
Site 62
S381
T
D
S
Q
T
E
D
S
Y
D
E
A
I
T
S
Site 63
Y382
D
S
Q
T
E
D
S
Y
D
E
A
I
T
S
E
Site 64
S388
S
Y
D
E
A
I
T
S
E
G
N
V
T
A
E
Site 65
T393
I
T
S
E
G
N
V
T
A
E
D
S
E
D
E
Site 66
S397
G
N
V
T
A
E
D
S
E
D
E
D
E
D
K
Site 67
T445
R
E
K
D
M
E
H
T
L
R
I
P
E
V
G
Site 68
S454
R
I
P
E
V
G
V
S
K
F
H
A
E
I
Y
Site 69
Y461
S
K
F
H
A
E
I
Y
F
D
H
D
L
Q
S
Site 70
Y469
F
D
H
D
L
Q
S
Y
V
L
V
D
Q
G
S
Site 71
S476
Y
V
L
V
D
Q
G
S
Q
N
G
T
I
V
N
Site 72
T480
D
Q
G
S
Q
N
G
T
I
V
N
G
K
Q
I
Site 73
T492
K
Q
I
L
Q
P
K
T
K
C
D
P
Y
V
L
Site 74
Y497
P
K
T
K
C
D
P
Y
V
L
E
H
G
D
E
Site 75
S513
K
I
G
E
T
V
L
S
F
H
I
H
P
G
S
Site 76
T522
H
I
H
P
G
S
D
T
C
D
G
C
E
P
G
Site 77
S543
R
L
D
K
K
D
E
S
F
V
G
P
T
L
S
Site 78
S550
S
F
V
G
P
T
L
S
K
E
E
K
E
L
E
Site 79
Y569
L
K
K
I
R
V
K
Y
G
L
Q
N
T
E
Y
Site 80
Y576
Y
G
L
Q
N
T
E
Y
E
D
E
K
T
L
K
Site 81
T581
T
E
Y
E
D
E
K
T
L
K
N
P
K
Y
K
Site 82
Y587
K
T
L
K
N
P
K
Y
K
D
R
A
G
K
R
Site 83
S600
K
R
R
E
Q
V
G
S
E
G
T
F
Q
R
D
Site 84
S612
Q
R
D
D
A
P
A
S
V
H
S
E
I
T
D
Site 85
S615
D
A
P
A
S
V
H
S
E
I
T
D
S
N
K
Site 86
S620
V
H
S
E
I
T
D
S
N
K
G
R
K
M
L
Site 87
T647
K
D
G
G
G
M
K
T
P
I
Q
L
Q
L
R
Site 88
T656
I
Q
L
Q
L
R
R
T
H
A
G
L
G
T
G
Site 89
T662
R
T
H
A
G
L
G
T
G
K
P
S
S
F
E
Site 90
S667
L
G
T
G
K
P
S
S
F
E
D
V
H
L
L
Site 91
T690
D
K
A
R
E
R
F
T
E
N
F
P
E
T
K
Site 92
T705
P
Q
K
D
D
P
G
T
M
P
W
V
K
G
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation