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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
JMJD5
Full Name:
Lysine-specific demethylase 8
Alias:
JmjC domain-containing protein 5;Jumonji domain-containing protein 5
Type:
Mass (Da):
47270
Number AA:
416
UniProt ID:
Q8N371
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T17
E
P
L
A
R
E
G
T
L
W
E
A
L
R
A
Site 2
S29
L
R
A
L
L
P
H
S
K
E
D
L
K
L
D
Site 3
S44
L
G
E
K
V
E
R
S
V
V
T
L
L
Q
R
Site 4
T53
V
T
L
L
Q
R
A
T
E
L
F
Y
E
G
R
Site 5
S67
R
R
D
E
C
L
Q
S
S
E
V
I
L
D
Y
Site 6
Y74
S
S
E
V
I
L
D
Y
S
W
E
K
L
N
T
Site 7
S75
S
E
V
I
L
D
Y
S
W
E
K
L
N
T
G
Site 8
Y95
D
K
D
W
R
R
V
Y
A
I
G
C
L
L
K
Site 9
T115
Q
A
P
E
D
A
N
T
V
A
A
A
L
R
V
Site 10
S158
G
K
R
P
A
R
G
S
L
P
E
Q
P
C
T
Site 11
T165
S
L
P
E
Q
P
C
T
K
K
A
R
A
D
H
Site 12
T183
P
D
V
K
L
E
K
T
V
P
R
L
H
R
P
Site 13
S191
V
P
R
L
H
R
P
S
L
Q
H
F
R
E
Q
Site 14
Y243
P
V
E
V
G
S
R
Y
T
D
E
E
W
S
Q
Site 15
T244
V
E
V
G
S
R
Y
T
D
E
E
W
S
Q
T
Site 16
T251
T
D
E
E
W
S
Q
T
L
M
T
V
N
E
F
Site 17
T254
E
W
S
Q
T
L
M
T
V
N
E
F
I
S
K
Site 18
Y262
V
N
E
F
I
S
K
Y
I
V
N
E
P
R
D
Site 19
Y272
N
E
P
R
D
V
G
Y
L
A
Q
H
Q
L
F
Site 20
S290
P
E
L
K
Q
D
I
S
I
P
D
Y
C
S
L
Site 21
Y294
Q
D
I
S
I
P
D
Y
C
S
L
G
D
G
E
Site 22
S296
I
S
I
P
D
Y
C
S
L
G
D
G
E
E
E
Site 23
T306
D
G
E
E
E
E
I
T
I
N
A
W
F
G
P
Site 24
T316
A
W
F
G
P
Q
G
T
I
S
P
L
H
Q
D
Site 25
S318
F
G
P
Q
G
T
I
S
P
L
H
Q
D
P
Q
Site 26
Y337
V
Q
V
M
G
R
K
Y
I
R
L
Y
S
P
Q
Site 27
Y341
G
R
K
Y
I
R
L
Y
S
P
Q
E
S
G
A
Site 28
S342
R
K
Y
I
R
L
Y
S
P
Q
E
S
G
A
L
Site 29
S346
R
L
Y
S
P
Q
E
S
G
A
L
Y
P
H
D
Site 30
Y350
P
Q
E
S
G
A
L
Y
P
H
D
T
H
L
L
Site 31
S361
T
H
L
L
H
N
T
S
Q
V
D
V
E
N
P
Site 32
Y401
I
P
V
K
Y
W
H
Y
V
R
A
L
D
L
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation