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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPM1K
Full Name:
Protein phosphatase 1K, mitochondrial
Alias:
EC 3.1.3.16; PP2C domain-containing protein phosphatase 1K; PP2C-kappa; PP2C-like mitochondrial protein; PP2CM; PP2C-type mitochondrial phosphoprotein phosphatase; Protein phosphatase 2C isoform kappa; PTMP
Type:
Protein serine/threonine phosphatase complex, Mitochondrion, Mitochondrial matrix protein
Mass (Da):
40997
Number AA:
372
UniProt ID:
Q8N3J5
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005759
GO:0008287
Uniprot
OncoNet
Molecular Function:
GO:0000287
GO:0030145
GO:0004722
PhosphoSite+
KinaseNET
Biological Process:
GO:0006470
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
V
R
R
R
V
L
L
S
S
R
L
L
Q
D
D
Site 2
S25
R
R
R
V
L
L
S
S
R
L
L
Q
D
D
R
Site 3
T35
L
Q
D
D
R
R
V
T
P
T
C
H
S
S
T
Site 4
T37
D
D
R
R
V
T
P
T
C
H
S
S
T
S
E
Site 5
S41
V
T
P
T
C
H
S
S
T
S
E
P
R
C
S
Site 6
S43
P
T
C
H
S
S
T
S
E
P
R
C
S
R
F
Site 7
S48
S
T
S
E
P
R
C
S
R
F
D
P
D
G
S
Site 8
S55
S
R
F
D
P
D
G
S
G
S
P
A
T
W
D
Site 9
S57
F
D
P
D
G
S
G
S
P
A
T
W
D
N
F
Site 10
S80
E
P
I
L
L
P
P
S
I
K
Y
G
K
P
I
Site 11
Y83
L
L
P
P
S
I
K
Y
G
K
P
I
P
K
I
Site 12
S99
L
E
N
V
G
C
A
S
Q
I
G
K
R
K
E
Site 13
Y122
Q
L
T
D
E
V
L
Y
F
A
V
Y
D
G
H
Site 14
S173
E
I
D
K
A
F
S
S
H
A
R
L
S
A
D
Site 15
T223
K
G
K
P
M
K
L
T
I
D
H
T
P
E
R
Site 16
T227
M
K
L
T
I
D
H
T
P
E
R
K
D
E
K
Site 17
S248
G
G
F
V
A
W
N
S
L
G
Q
P
H
V
N
Site 18
S263
G
R
L
A
M
T
R
S
I
G
D
L
D
L
K
Site 19
T280
G
V
I
A
E
P
E
T
K
R
I
K
L
H
H
Site 20
S291
K
L
H
H
A
D
D
S
F
L
V
L
T
T
D
Site 21
T297
D
S
F
L
V
L
T
T
D
G
I
N
F
M
V
Site 22
S339
Q
Y
G
T
E
D
N
S
T
A
V
V
V
P
F
Site 23
T340
Y
G
T
E
D
N
S
T
A
V
V
V
P
F
G
Site 24
Y352
P
F
G
A
W
G
K
Y
K
N
S
E
I
N
F
Site 25
S355
A
W
G
K
Y
K
N
S
E
I
N
F
S
F
S
Site 26
S360
K
N
S
E
I
N
F
S
F
S
R
S
F
A
S
Site 27
S362
S
E
I
N
F
S
F
S
R
S
F
A
S
S
G
Site 28
S364
I
N
F
S
F
S
R
S
F
A
S
S
G
R
W
Site 29
S367
S
F
S
R
S
F
A
S
S
G
R
W
A
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation