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Updated November 2019
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Protein Info
Short Name:
CMYA5
Full Name:
Cardiomyopathy-associated protein 5
Alias:
Dystrobrevin-binding protein 2;Genethonin-3;Myospryn;SPRY domain-containing protein 2;Tripartite motif-containing protein 76
Type:
Mass (Da):
449211
Number AA:
4069
UniProt ID:
Q8N3K9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
S
R
D
S
N
H
A
G
E
S
F
Site 2
S12
D
S
N
H
A
G
E
S
F
L
G
S
D
G
D
Site 3
S16
A
G
E
S
F
L
G
S
D
G
D
E
E
A
T
Site 4
T39
S
E
G
E
E
D
E
T
A
A
E
S
E
E
E
Site 5
S49
E
S
E
E
E
P
D
S
R
L
S
D
Q
D
E
Site 6
S52
E
E
P
D
S
R
L
S
D
Q
D
E
E
G
K
Site 7
Y64
E
G
K
I
K
Q
E
Y
I
I
S
D
P
S
F
Site 8
S67
I
K
Q
E
Y
I
I
S
D
P
S
F
S
M
V
Site 9
T75
D
P
S
F
S
M
V
T
V
Q
R
E
D
S
G
Site 10
S81
V
T
V
Q
R
E
D
S
G
I
T
W
E
T
N
Site 11
T87
D
S
G
I
T
W
E
T
N
S
S
R
S
S
T
Site 12
S89
G
I
T
W
E
T
N
S
S
R
S
S
T
P
W
Site 13
S90
I
T
W
E
T
N
S
S
R
S
S
T
P
W
A
Site 14
S93
E
T
N
S
S
R
S
S
T
P
W
A
S
E
E
Site 15
T94
T
N
S
S
R
S
S
T
P
W
A
S
E
E
S
Site 16
S98
R
S
S
T
P
W
A
S
E
E
S
Q
T
S
G
Site 17
S101
T
P
W
A
S
E
E
S
Q
T
S
G
V
C
S
Site 18
S104
A
S
E
E
S
Q
T
S
G
V
C
S
R
E
G
Site 19
S108
S
Q
T
S
G
V
C
S
R
E
G
S
T
V
N
Site 20
S112
G
V
C
S
R
E
G
S
T
V
N
S
P
P
G
Site 21
S116
R
E
G
S
T
V
N
S
P
P
G
N
V
S
F
Site 22
S122
N
S
P
P
G
N
V
S
F
I
V
D
E
V
K
Site 23
T135
V
K
K
V
R
K
R
T
H
K
S
K
H
G
S
Site 24
S138
V
R
K
R
T
H
K
S
K
H
G
S
P
S
L
Site 25
S142
T
H
K
S
K
H
G
S
P
S
L
R
R
K
G
Site 26
S144
K
S
K
H
G
S
P
S
L
R
R
K
G
N
R
Site 27
S155
K
G
N
R
K
R
N
S
F
E
S
Q
D
V
P
Site 28
S158
R
K
R
N
S
F
E
S
Q
D
V
P
T
N
K
Site 29
T163
F
E
S
Q
D
V
P
T
N
K
K
G
S
P
L
Site 30
S168
V
P
T
N
K
K
G
S
P
L
T
S
A
S
Q
Site 31
T171
N
K
K
G
S
P
L
T
S
A
S
Q
V
L
T
Site 32
S172
K
K
G
S
P
L
T
S
A
S
Q
V
L
T
T
Site 33
S174
G
S
P
L
T
S
A
S
Q
V
L
T
T
E
K
Site 34
T178
T
S
A
S
Q
V
L
T
T
E
K
E
K
S
Y
Site 35
S184
L
T
T
E
K
E
K
S
Y
T
G
I
Y
D
K
Site 36
T186
T
E
K
E
K
S
Y
T
G
I
Y
D
K
A
R
Site 37
T197
D
K
A
R
K
K
K
T
T
S
N
T
P
P
I
Site 38
T198
K
A
R
K
K
K
T
T
S
N
T
P
P
I
T
Site 39
S199
A
R
K
K
K
T
T
S
N
T
P
P
I
T
G
Site 40
T201
K
K
K
T
T
S
N
T
P
P
I
T
G
A
I
Site 41
Y209
P
P
I
T
G
A
I
Y
K
E
H
K
P
L
V
Site 42
S234
Y
K
I
K
M
F
N
S
V
K
E
E
L
I
P
Site 43
Y252
Y
G
T
L
P
K
G
Y
V
I
K
E
I
H
Y
Site 44
S266
Y
R
K
G
K
D
A
S
I
S
L
E
P
D
L
Site 45
S268
K
G
K
D
A
S
I
S
L
E
P
D
L
D
N
Site 46
S276
L
E
P
D
L
D
N
S
G
S
N
T
V
S
K
Site 47
S278
P
D
L
D
N
S
G
S
N
T
V
S
K
T
R
Site 48
T280
L
D
N
S
G
S
N
T
V
S
K
T
R
K
L
Site 49
S282
N
S
G
S
N
T
V
S
K
T
R
K
L
V
A
Site 50
S308
P
P
W
R
G
A
L
S
K
G
S
E
S
L
T
Site 51
S313
A
L
S
K
G
S
E
S
L
T
L
M
F
S
H
Site 52
T315
S
K
G
S
E
S
L
T
L
M
F
S
H
E
D
Site 53
S319
E
S
L
T
L
M
F
S
H
E
D
Q
K
K
I
Site 54
S330
Q
K
K
I
Y
A
D
S
P
L
N
A
T
S
A
Site 55
T341
A
T
S
A
L
E
H
T
V
P
S
Y
S
S
S
Site 56
S344
A
L
E
H
T
V
P
S
Y
S
S
S
G
R
A
Site 57
Y345
L
E
H
T
V
P
S
Y
S
S
S
G
R
A
E
Site 58
S346
E
H
T
V
P
S
Y
S
S
S
G
R
A
E
Q
Site 59
S348
T
V
P
S
Y
S
S
S
G
R
A
E
Q
G
I
Site 60
S360
Q
G
I
Q
L
R
H
S
Q
S
V
P
Q
Q
P
Site 61
S362
I
Q
L
R
H
S
Q
S
V
P
Q
Q
P
E
D
Site 62
S380
P
H
E
V
E
P
P
S
V
T
P
D
T
P
A
Site 63
T382
E
V
E
P
P
S
V
T
P
D
T
P
A
T
M
Site 64
T385
P
P
S
V
T
P
D
T
P
A
T
M
F
L
R
Site 65
T394
A
T
M
F
L
R
T
T
K
E
E
C
E
L
A
Site 66
S402
K
E
E
C
E
L
A
S
P
G
T
A
A
S
E
Site 67
S408
A
S
P
G
T
A
A
S
E
N
D
S
S
V
S
Site 68
S412
T
A
A
S
E
N
D
S
S
V
S
P
S
F
A
Site 69
S413
A
A
S
E
N
D
S
S
V
S
P
S
F
A
N
Site 70
S415
S
E
N
D
S
S
V
S
P
S
F
A
N
E
V
Site 71
S417
N
D
S
S
V
S
P
S
F
A
N
E
V
K
K
Site 72
Y428
E
V
K
K
E
D
V
Y
S
A
H
H
S
I
S
Site 73
S429
V
K
K
E
D
V
Y
S
A
H
H
S
I
S
L
Site 74
S433
D
V
Y
S
A
H
H
S
I
S
L
E
A
A
S
Site 75
S435
Y
S
A
H
H
S
I
S
L
E
A
A
S
P
G
Site 76
S446
A
S
P
G
L
A
A
S
T
Q
D
G
L
D
P
Site 77
S462
Q
E
Q
P
D
L
T
S
I
E
R
A
E
P
V
Site 78
S470
I
E
R
A
E
P
V
S
A
K
L
T
P
T
H
Site 79
T474
E
P
V
S
A
K
L
T
P
T
H
P
S
V
K
Site 80
S492
E
E
N
M
L
E
P
S
I
S
L
S
E
P
L
Site 81
S496
L
E
P
S
I
S
L
S
E
P
L
M
L
E
E
Site 82
T511
P
E
K
E
E
I
E
T
S
L
P
I
A
I
T
Site 83
S512
E
K
E
E
I
E
T
S
L
P
I
A
I
T
P
Site 84
T518
T
S
L
P
I
A
I
T
P
E
P
E
D
S
N
Site 85
S524
I
T
P
E
P
E
D
S
N
L
V
E
E
E
I
Site 86
Y536
E
E
I
V
E
L
D
Y
P
E
S
P
L
V
S
Site 87
S539
V
E
L
D
Y
P
E
S
P
L
V
S
E
K
P
Site 88
S543
Y
P
E
S
P
L
V
S
E
K
P
F
P
P
H
Site 89
S552
K
P
F
P
P
H
M
S
P
E
V
E
H
K
E
Site 90
S578
S
P
E
H
V
A
L
S
E
E
E
R
E
E
I
Site 91
S587
E
E
R
E
E
I
A
S
V
S
T
G
S
A
F
Site 92
S596
S
T
G
S
A
F
V
S
E
Y
S
V
P
Q
D
Site 93
Y598
G
S
A
F
V
S
E
Y
S
V
P
Q
D
L
N
Site 94
S599
S
A
F
V
S
E
Y
S
V
P
Q
D
L
N
H
Site 95
S619
E
G
E
P
V
P
P
S
N
V
E
A
I
A
E
Site 96
S631
I
A
E
H
A
V
L
S
E
E
E
N
E
E
F
Site 97
Y641
E
N
E
E
F
E
A
Y
S
P
A
A
A
P
T
Site 98
S642
N
E
E
F
E
A
Y
S
P
A
A
A
P
T
S
Site 99
T648
Y
S
P
A
A
A
P
T
S
E
S
S
L
S
P
Site 100
S649
S
P
A
A
A
P
T
S
E
S
S
L
S
P
S
Site 101
S652
A
A
P
T
S
E
S
S
L
S
P
S
T
T
E
Site 102
S654
P
T
S
E
S
S
L
S
P
S
T
T
E
K
T
Site 103
S656
S
E
S
S
L
S
P
S
T
T
E
K
T
S
E
Site 104
T657
E
S
S
L
S
P
S
T
T
E
K
T
S
E
N
Site 105
T658
S
S
L
S
P
S
T
T
E
K
T
S
E
N
Q
Site 106
T661
S
P
S
T
T
E
K
T
S
E
N
Q
S
P
L
Site 107
S662
P
S
T
T
E
K
T
S
E
N
Q
S
P
L
F
Site 108
S666
E
K
T
S
E
N
Q
S
P
L
F
S
T
V
T
Site 109
S670
E
N
Q
S
P
L
F
S
T
V
T
P
E
Y
M
Site 110
T671
N
Q
S
P
L
F
S
T
V
T
P
E
Y
M
V
Site 111
Y676
F
S
T
V
T
P
E
Y
M
V
L
S
G
D
E
Site 112
S680
T
P
E
Y
M
V
L
S
G
D
E
A
S
E
S
Site 113
S685
V
L
S
G
D
E
A
S
E
S
G
C
Y
T
P
Site 114
S687
S
G
D
E
A
S
E
S
G
C
Y
T
P
D
S
Site 115
Y690
E
A
S
E
S
G
C
Y
T
P
D
S
T
S
A
Site 116
T691
A
S
E
S
G
C
Y
T
P
D
S
T
S
A
S
Site 117
S694
S
G
C
Y
T
P
D
S
T
S
A
S
E
Y
S
Site 118
T695
G
C
Y
T
P
D
S
T
S
A
S
E
Y
S
V
Site 119
S696
C
Y
T
P
D
S
T
S
A
S
E
Y
S
V
P
Site 120
S698
T
P
D
S
T
S
A
S
E
Y
S
V
P
S
L
Site 121
Y700
D
S
T
S
A
S
E
Y
S
V
P
S
L
A
T
Site 122
S701
S
T
S
A
S
E
Y
S
V
P
S
L
A
T
K
Site 123
S704
A
S
E
Y
S
V
P
S
L
A
T
K
E
S
L
Site 124
S710
P
S
L
A
T
K
E
S
L
K
K
T
I
D
R
Site 125
T714
T
K
E
S
L
K
K
T
I
D
R
K
S
P
L
Site 126
S719
K
K
T
I
D
R
K
S
P
L
I
L
K
G
V
Site 127
Y729
I
L
K
G
V
S
E
Y
M
I
P
S
E
E
K
Site 128
S733
V
S
E
Y
M
I
P
S
E
E
K
E
D
T
G
Site 129
T739
P
S
E
E
K
E
D
T
G
S
F
T
P
A
V
Site 130
S741
E
E
K
E
D
T
G
S
F
T
P
A
V
A
P
Site 131
T743
K
E
D
T
G
S
F
T
P
A
V
A
P
A
S
Site 132
S750
T
P
A
V
A
P
A
S
E
P
S
L
S
P
S
Site 133
S753
V
A
P
A
S
E
P
S
L
S
P
S
T
T
E
Site 134
S755
P
A
S
E
P
S
L
S
P
S
T
T
E
K
T
Site 135
S757
S
E
P
S
L
S
P
S
T
T
E
K
T
S
E
Site 136
T758
E
P
S
L
S
P
S
T
T
E
K
T
S
E
C
Site 137
T759
P
S
L
S
P
S
T
T
E
K
T
S
E
C
Q
Site 138
T762
S
P
S
T
T
E
K
T
S
E
C
Q
S
P
L
Site 139
S763
P
S
T
T
E
K
T
S
E
C
Q
S
P
L
P
Site 140
S767
E
K
T
S
E
C
Q
S
P
L
P
S
T
A
T
Site 141
S771
E
C
Q
S
P
L
P
S
T
A
T
S
E
H
V
Site 142
S775
P
L
P
S
T
A
T
S
E
H
V
V
P
S
E
Site 143
S788
S
E
G
E
D
L
G
S
E
R
F
T
P
D
S
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Site 448
T2850
P
E
R
H
T
V
H
T
I
Q
T
S
K
D
D
Site 449
T2858
I
Q
T
S
K
D
D
T
S
D
V
P
K
Q
S
Site 450
S2859
Q
T
S
K
D
D
T
S
D
V
P
K
Q
S
V
Site 451
S2865
T
S
D
V
P
K
Q
S
V
L
V
S
K
H
H
Site 452
S2869
P
K
Q
S
V
L
V
S
K
H
H
L
E
A
A
Site 453
S2886
T
R
V
K
E
P
L
S
S
A
K
S
N
Y
A
Site 454
S2887
R
V
K
E
P
L
S
S
A
K
S
N
Y
A
Q
Site 455
S2890
E
P
L
S
S
A
K
S
N
Y
A
Q
F
I
S
Site 456
S2897
S
N
Y
A
Q
F
I
S
N
T
S
A
S
N
A
Site 457
T2920
M
P
K
E
P
E
D
T
Y
A
K
G
E
D
F
Site 458
Y2921
P
K
E
P
E
D
T
Y
A
K
G
E
D
F
T
Site 459
T2928
Y
A
K
G
E
D
F
T
V
T
S
K
P
A
G
Site 460
T2930
K
G
E
D
F
T
V
T
S
K
P
A
G
L
S
Site 461
S2931
G
E
D
F
T
V
T
S
K
P
A
G
L
S
E
Site 462
S2937
T
S
K
P
A
G
L
S
E
D
Q
K
T
A
F
Site 463
T2942
G
L
S
E
D
Q
K
T
A
F
S
I
I
S
E
Site 464
S2964
H
A
P
A
F
I
S
S
I
D
Q
E
E
S
E
Site 465
S2970
S
S
I
D
Q
E
E
S
E
Q
M
Q
D
K
L
Site 466
S2985
E
Y
L
E
E
K
A
S
F
K
T
I
P
L
P
Site 467
S2995
T
I
P
L
P
D
D
S
E
T
V
A
C
H
K
Site 468
T2997
P
L
P
D
D
S
E
T
V
A
C
H
K
T
L
Site 469
T3003
E
T
V
A
C
H
K
T
L
K
S
R
L
E
D
Site 470
S3006
A
C
H
K
T
L
K
S
R
L
E
D
E
K
V
Site 471
T3014
R
L
E
D
E
K
V
T
P
L
K
E
N
K
Q
Site 472
T3027
K
Q
K
E
T
H
K
T
K
E
E
I
S
T
D
Site 473
T3033
K
T
K
E
E
I
S
T
D
S
E
T
D
L
S
Site 474
S3035
K
E
E
I
S
T
D
S
E
T
D
L
S
F
I
Site 475
T3037
E
I
S
T
D
S
E
T
D
L
S
F
I
Q
P
Site 476
S3040
T
D
S
E
T
D
L
S
F
I
Q
P
T
I
P
Site 477
Y3052
T
I
P
S
E
E
D
Y
F
E
K
Y
T
L
I
Site 478
Y3056
E
E
D
Y
F
E
K
Y
T
L
I
D
Y
N
I
Site 479
Y3061
E
K
Y
T
L
I
D
Y
N
I
S
P
D
P
E
Site 480
S3064
T
L
I
D
Y
N
I
S
P
D
P
E
K
Q
K
Site 481
S3083
L
N
V
E
E
K
L
S
K
E
V
T
E
E
T
Site 482
T3087
E
K
L
S
K
E
V
T
E
E
T
I
S
F
P
Site 483
S3092
E
V
T
E
E
T
I
S
F
P
V
S
S
V
E
Site 484
S3100
F
P
V
S
S
V
E
S
A
L
E
H
E
Y
D
Site 485
Y3106
E
S
A
L
E
H
E
Y
D
L
V
K
L
D
E
Site 486
S3114
D
L
V
K
L
D
E
S
F
Y
G
P
E
K
G
Site 487
Y3116
V
K
L
D
E
S
F
Y
G
P
E
K
G
H
N
Site 488
S3126
E
K
G
H
N
I
L
S
H
P
E
T
Q
S
Q
Site 489
T3130
N
I
L
S
H
P
E
T
Q
S
Q
N
S
A
D
Site 490
S3132
L
S
H
P
E
T
Q
S
Q
N
S
A
D
R
N
Site 491
S3141
N
S
A
D
R
N
V
S
K
D
T
K
R
D
V
Site 492
S3150
D
T
K
R
D
V
D
S
K
S
P
G
M
P
L
Site 493
S3152
K
R
D
V
D
S
K
S
P
G
M
P
L
F
E
Site 494
S3166
E
A
E
E
G
V
L
S
R
T
Q
I
F
P
T
Site 495
Y3193
P
P
A
L
A
F
L
Y
K
D
L
Y
E
E
A
Site 496
Y3197
A
F
L
Y
K
D
L
Y
E
E
A
V
G
E
K
Site 497
S3212
K
K
E
E
E
T
A
S
E
G
D
S
V
N
S
Site 498
S3216
E
T
A
S
E
G
D
S
V
N
S
E
A
S
F
Site 499
S3219
S
E
G
D
S
V
N
S
E
A
S
F
P
S
R
Site 500
S3222
D
S
V
N
S
E
A
S
F
P
S
R
N
S
D
Site 501
S3228
A
S
F
P
S
R
N
S
D
T
D
D
G
T
G
Site 502
T3230
F
P
S
R
N
S
D
T
D
D
G
T
G
I
Y
Site 503
T3234
N
S
D
T
D
D
G
T
G
I
Y
F
E
K
Y
Site 504
Y3237
T
D
D
G
T
G
I
Y
F
E
K
Y
I
L
K
Site 505
S3252
D
D
I
L
H
D
T
S
L
T
Q
K
D
Q
G
Site 506
S3272
K
R
V
G
K
D
D
S
Y
Q
P
I
A
A
E
Site 507
Y3273
R
V
G
K
D
D
S
Y
Q
P
I
A
A
E
G
Site 508
T3288
E
I
W
G
K
F
G
T
I
C
R
E
K
S
L
Site 509
S3294
G
T
I
C
R
E
K
S
L
E
E
Q
K
G
V
Site 510
Y3302
L
E
E
Q
K
G
V
Y
G
E
G
E
S
V
D
Site 511
S3307
G
V
Y
G
E
G
E
S
V
D
H
V
E
T
V
Site 512
T3333
T
E
D
V
R
V
A
T
Q
K
I
S
Y
A
V
Site 513
Y3338
V
A
T
Q
K
I
S
Y
A
V
P
F
E
D
T
Site 514
S3366
G
N
E
V
G
N
A
S
P
E
V
N
L
N
V
Site 515
S3395
A
T
H
V
Q
E
T
S
L
E
E
P
K
I
L
Site 516
S3415
S
E
E
R
L
R
N
S
P
V
Q
D
E
Y
E
Site 517
Y3421
N
S
P
V
Q
D
E
Y
E
F
T
E
S
L
H
Site 518
T3424
V
Q
D
E
Y
E
F
T
E
S
L
H
N
E
V
Site 519
S3426
D
E
Y
E
F
T
E
S
L
H
N
E
V
V
P
Site 520
S3438
V
V
P
Q
D
I
L
S
E
E
L
S
S
E
S
Site 521
S3442
D
I
L
S
E
E
L
S
S
E
S
T
P
E
D
Site 522
S3443
I
L
S
E
E
L
S
S
E
S
T
P
E
D
V
Site 523
T3446
E
E
L
S
S
E
S
T
P
E
D
V
L
S
Q
Site 524
S3452
S
T
P
E
D
V
L
S
Q
G
K
E
S
F
E
Site 525
S3457
V
L
S
Q
G
K
E
S
F
E
H
I
S
E
N
Site 526
S3462
K
E
S
F
E
H
I
S
E
N
E
F
A
S
E
Site 527
S3468
I
S
E
N
E
F
A
S
E
A
E
Q
S
T
P
Site 528
S3473
F
A
S
E
A
E
Q
S
T
P
A
E
Q
K
E
Site 529
T3474
A
S
E
A
E
Q
S
T
P
A
E
Q
K
E
L
Site 530
S3483
A
E
Q
K
E
L
G
S
E
R
K
E
E
D
Q
Site 531
S3492
R
K
E
E
D
Q
L
S
S
E
V
V
T
E
K
Site 532
S3507
A
Q
K
E
L
K
K
S
Q
I
D
T
Y
C
Y
Site 533
T3511
L
K
K
S
Q
I
D
T
Y
C
Y
T
C
K
C
Site 534
Y3512
K
K
S
Q
I
D
T
Y
C
Y
T
C
K
C
P
Site 535
Y3514
S
Q
I
D
T
Y
C
Y
T
C
K
C
P
I
S
Site 536
S3521
Y
T
C
K
C
P
I
S
A
T
D
K
V
F
G
Site 537
T3529
A
T
D
K
V
F
G
T
H
K
D
H
E
V
S
Site 538
S3560
L
E
N
L
Q
E
K
S
L
R
I
E
A
F
V
Site 539
T3576
E
I
E
S
F
F
N
T
I
E
E
N
C
S
K
Site 540
S3582
N
T
I
E
E
N
C
S
K
N
E
K
R
L
E
Site 541
Y3603
M
K
K
V
L
A
Q
Y
D
E
K
A
Q
S
F
Site 542
S3609
Q
Y
D
E
K
A
Q
S
F
E
E
V
K
K
K
Site 543
S3631
Q
M
V
H
F
L
Q
S
M
D
T
A
K
D
T
Site 544
T3634
H
F
L
Q
S
M
D
T
A
K
D
T
L
E
T
Site 545
T3638
S
M
D
T
A
K
D
T
L
E
T
I
V
R
E
Site 546
S3657
D
E
A
V
F
L
T
S
F
E
E
I
N
E
R
Site 547
S3667
E
I
N
E
R
L
L
S
A
M
E
S
T
A
S
Site 548
S3671
R
L
L
S
A
M
E
S
T
A
S
L
E
K
M
Site 549
S3674
S
A
M
E
S
T
A
S
L
E
K
M
P
A
A
Site 550
Y3688
A
F
S
L
F
E
H
Y
D
D
S
S
A
R
S
Site 551
S3691
L
F
E
H
Y
D
D
S
S
A
R
S
D
Q
M
Site 552
S3692
F
E
H
Y
D
D
S
S
A
R
S
D
Q
M
L
Site 553
S3695
Y
D
D
S
S
A
R
S
D
Q
M
L
K
Q
V
Site 554
S3717
L
E
P
Q
E
P
N
S
A
T
S
T
T
I
A
Site 555
T3721
E
P
N
S
A
T
S
T
T
I
A
V
Y
W
S
Site 556
Y3741
V
I
D
S
F
Q
V
Y
C
M
E
E
P
Q
D
Site 557
T3762
L
V
E
E
Y
R
L
T
V
K
E
S
Y
C
I
Site 558
Y3779
D
L
E
P
D
R
C
Y
Q
V
W
V
M
A
V
Site 559
S3795
F
T
G
C
S
L
P
S
E
R
A
I
F
R
T
Site 560
T3802
S
E
R
A
I
F
R
T
A
P
S
T
P
V
I
Site 561
T3806
I
F
R
T
A
P
S
T
P
V
I
R
A
E
D
Site 562
T3828
A
T
I
R
W
R
P
T
T
P
E
A
T
E
T
Site 563
T3829
T
I
R
W
R
P
T
T
P
E
A
T
E
T
Y
Site 564
T3835
T
T
P
E
A
T
E
T
Y
T
L
E
Y
C
R
Site 565
Y3840
T
E
T
Y
T
L
E
Y
C
R
Q
H
S
P
E
Site 566
S3845
L
E
Y
C
R
Q
H
S
P
E
G
E
G
L
R
Site 567
S3853
P
E
G
E
G
L
R
S
F
S
G
I
K
G
L
Site 568
S3855
G
E
G
L
R
S
F
S
G
I
K
G
L
Q
L
Site 569
Y3872
N
L
Q
P
N
D
N
Y
F
F
Y
V
R
A
I
Site 570
Y3875
P
N
D
N
Y
F
F
Y
V
R
A
I
N
A
F
Site 571
S3894
Q
S
E
A
A
L
I
S
T
R
G
T
R
F
L
Site 572
S3921
S
S
S
G
T
V
I
S
F
G
E
R
R
R
L
Site 573
T3929
F
G
E
R
R
R
L
T
E
I
P
S
V
L
G
Site 574
S3933
R
R
L
T
E
I
P
S
V
L
G
E
E
L
P
Site 575
Y3980
G
Q
G
E
T
S
W
Y
M
H
C
S
E
P
Q
Site 576
Y3989
H
C
S
E
P
Q
R
Y
T
F
F
Y
S
G
I
Site 577
Y3993
P
Q
R
Y
T
F
F
Y
S
G
I
V
S
D
V
Site 578
T4003
I
V
S
D
V
H
V
T
E
R
P
A
R
V
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation