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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SYNPO
Full Name:
Synaptopodin
Alias:
KIAA1029
Type:
Unknown function
Mass (Da):
99463
Number AA:
929
UniProt ID:
Q8N3V7
International Prot ID:
IPI00027258
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0015629
GO:0005737
GO:0043197
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0032233
GO:0051492
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
P
P
P
P
L
A
P
S
E
G
R
P
T
P
C
Site 2
T19
A
P
S
E
G
R
P
T
P
C
A
F
Q
I
P
Site 3
S40
L
A
L
E
A
E
E
S
S
G
E
E
G
L
Q
Site 4
S41
A
L
E
A
E
E
S
S
G
E
E
G
L
Q
G
Site 5
T53
L
Q
G
E
V
G
P
T
D
L
E
E
D
E
G
Site 6
S64
E
D
E
G
V
S
R
S
G
D
D
S
A
C
R
Site 7
S68
V
S
R
S
G
D
D
S
A
C
R
V
T
Q
G
Site 8
T73
D
D
S
A
C
R
V
T
Q
G
T
P
Q
L
P
Site 9
T76
A
C
R
V
T
Q
G
T
P
Q
L
P
K
A
L
Site 10
S89
A
L
G
I
Q
P
P
S
C
S
R
E
E
Q
G
Site 11
S98
S
R
E
E
Q
G
A
S
Q
H
D
D
R
A
S
Site 12
S105
S
Q
H
D
D
R
A
S
Q
D
W
D
V
V
K
Site 13
T118
V
K
A
G
Q
M
M
T
A
S
P
S
P
G
P
Site 14
S120
A
G
Q
M
M
T
A
S
P
S
P
G
P
G
P
Site 15
S122
Q
M
M
T
A
S
P
S
P
G
P
G
P
R
V
Site 16
S138
Q
K
P
A
L
G
R
S
T
S
L
T
E
K
D
Site 17
T139
K
P
A
L
G
R
S
T
S
L
T
E
K
D
L
Site 18
S140
P
A
L
G
R
S
T
S
L
T
E
K
D
L
K
Site 19
T142
L
G
R
S
T
S
L
T
E
K
D
L
K
E
A
Site 20
T161
Q
Q
I
A
A
Q
L
T
T
P
P
S
S
N
S
Site 21
T162
Q
I
A
A
Q
L
T
T
P
P
S
S
N
S
R
Site 22
S165
A
Q
L
T
T
P
P
S
S
N
S
R
G
V
Q
Site 23
S166
Q
L
T
T
P
P
S
S
N
S
R
G
V
Q
L
Site 24
S168
T
T
P
P
S
S
N
S
R
G
V
Q
L
F
N
Site 25
T185
R
Q
R
V
N
E
F
T
L
E
S
H
G
Q
R
Site 26
S197
G
Q
R
G
Q
K
P
S
Q
E
S
L
R
V
L
Site 27
S200
G
Q
K
P
S
Q
E
S
L
R
V
L
P
S
S
Site 28
S206
E
S
L
R
V
L
P
S
S
L
P
G
H
A
P
Site 29
S207
S
L
R
V
L
P
S
S
L
P
G
H
A
P
G
Site 30
S216
P
G
H
A
P
G
L
S
L
S
S
T
S
L
P
Site 31
S218
H
A
P
G
L
S
L
S
S
T
S
L
P
E
P
Site 32
T220
P
G
L
S
L
S
S
T
S
L
P
E
P
G
P
Site 33
S221
G
L
S
L
S
S
T
S
L
P
E
P
G
P
P
Site 34
S232
P
G
P
P
R
H
P
S
P
Q
S
P
D
R
G
Site 35
S235
P
R
H
P
S
P
Q
S
P
D
R
G
V
P
G
Site 36
Y248
P
G
H
S
M
E
G
Y
S
E
E
A
S
L
L
Site 37
S249
G
H
S
M
E
G
Y
S
E
E
A
S
L
L
R
Site 38
S253
E
G
Y
S
E
E
A
S
L
L
R
H
L
E
K
Site 39
S263
R
H
L
E
K
V
A
S
E
E
E
E
V
P
L
Site 40
S289
T
A
N
G
L
H
L
S
Q
N
R
E
A
Q
Q
Site 41
S297
Q
N
R
E
A
Q
Q
S
S
P
A
P
P
P
A
Site 42
S298
N
R
E
A
Q
Q
S
S
P
A
P
P
P
A
E
Site 43
S308
P
P
P
A
E
V
H
S
P
A
A
D
V
N
Q
Site 44
S319
D
V
N
Q
N
L
A
S
P
S
A
T
L
T
T
Site 45
T323
N
L
A
S
P
S
A
T
L
T
T
P
T
S
N
Site 46
T325
A
S
P
S
A
T
L
T
T
P
T
S
N
S
S
Site 47
T326
S
P
S
A
T
L
T
T
P
T
S
N
S
S
H
Site 48
T328
S
A
T
L
T
T
P
T
S
N
S
S
H
N
P
Site 49
S329
A
T
L
T
T
P
T
S
N
S
S
H
N
P
P
Site 50
S332
T
T
P
T
S
N
S
S
H
N
P
P
A
T
D
Site 51
T338
S
S
H
N
P
P
A
T
D
V
N
Q
N
P
P
Site 52
T347
V
N
Q
N
P
P
A
T
V
V
P
Q
S
L
P
Site 53
S356
V
P
Q
S
L
P
L
S
S
I
Q
Q
N
S
S
Site 54
S357
P
Q
S
L
P
L
S
S
I
Q
Q
N
S
S
E
Site 55
S363
S
S
I
Q
Q
N
S
S
E
A
Q
L
P
S
N
Site 56
S369
S
S
E
A
Q
L
P
S
N
G
T
G
P
A
S
Site 57
S376
S
N
G
T
G
P
A
S
K
P
S
T
L
C
A
Site 58
T380
G
P
A
S
K
P
S
T
L
C
A
D
G
Q
P
Site 59
S405
T
L
L
I
D
K
V
S
T
P
A
T
T
T
S
Site 60
T406
L
L
I
D
K
V
S
T
P
A
T
T
T
S
T
Site 61
T409
D
K
V
S
T
P
A
T
T
T
S
T
F
S
R
Site 62
S412
S
T
P
A
T
T
T
S
T
F
S
R
E
A
T
Site 63
T413
T
P
A
T
T
T
S
T
F
S
R
E
A
T
L
Site 64
S415
A
T
T
T
S
T
F
S
R
E
A
T
L
I
P
Site 65
T419
S
T
F
S
R
E
A
T
L
I
P
S
S
R
P
Site 66
S423
R
E
A
T
L
I
P
S
S
R
P
P
A
S
D
Site 67
S424
E
A
T
L
I
P
S
S
R
P
P
A
S
D
F
Site 68
S429
P
S
S
R
P
P
A
S
D
F
M
S
S
S
L
Site 69
T460
M
S
G
R
A
A
A
T
T
P
T
K
V
Y
S
Site 70
T461
S
G
R
A
A
A
T
T
P
T
K
V
Y
S
E
Site 71
T463
R
A
A
A
T
T
P
T
K
V
Y
S
E
V
H
Site 72
Y466
A
T
T
P
T
K
V
Y
S
E
V
H
F
T
L
Site 73
S467
T
T
P
T
K
V
Y
S
E
V
H
F
T
L
A
Site 74
S478
F
T
L
A
K
P
P
S
V
V
N
R
T
A
R
Site 75
T483
P
P
S
V
V
N
R
T
A
R
P
F
G
I
Q
Site 76
S496
I
Q
A
P
G
G
T
S
Q
M
E
R
S
P
M
Site 77
S501
G
T
S
Q
M
E
R
S
P
M
L
E
R
R
H
Site 78
S520
A
P
A
P
Q
P
P
S
L
P
D
R
S
P
R
Site 79
S525
P
P
S
L
P
D
R
S
P
R
P
Q
R
H
I
Site 80
S536
Q
R
H
I
M
S
R
S
P
M
V
E
R
R
M
Site 81
S548
R
R
M
M
G
Q
R
S
P
A
S
E
R
R
P
Site 82
S551
M
G
Q
R
S
P
A
S
E
R
R
P
L
G
N
Site 83
T560
R
R
P
L
G
N
F
T
A
P
P
T
Y
T
E
Site 84
T564
G
N
F
T
A
P
P
T
Y
T
E
T
L
S
T
Site 85
T568
A
P
P
T
Y
T
E
T
L
S
T
A
P
L
A
Site 86
S570
P
T
Y
T
E
T
L
S
T
A
P
L
A
S
W
Site 87
S576
L
S
T
A
P
L
A
S
W
V
R
S
P
P
S
Site 88
S580
P
L
A
S
W
V
R
S
P
P
S
Y
S
V
L
Site 89
S583
S
W
V
R
S
P
P
S
Y
S
V
L
Y
P
S
Site 90
Y584
W
V
R
S
P
P
S
Y
S
V
L
Y
P
S
S
Site 91
S585
V
R
S
P
P
S
Y
S
V
L
Y
P
S
S
D
Site 92
Y588
P
P
S
Y
S
V
L
Y
P
S
S
D
P
K
S
Site 93
S590
S
Y
S
V
L
Y
P
S
S
D
P
K
S
S
H
Site 94
S591
Y
S
V
L
Y
P
S
S
D
P
K
S
S
H
L
Site 95
S595
Y
P
S
S
D
P
K
S
S
H
L
K
G
Q
A
Site 96
S596
P
S
S
D
P
K
S
S
H
L
K
G
Q
A
V
Site 97
S606
K
G
Q
A
V
P
A
S
K
T
G
I
L
E
E
Site 98
S614
K
T
G
I
L
E
E
S
M
A
R
R
G
S
R
Site 99
S620
E
S
M
A
R
R
G
S
R
K
S
M
F
T
F
Site 100
S623
A
R
R
G
S
R
K
S
M
F
T
F
V
E
K
Site 101
T626
G
S
R
K
S
M
F
T
F
V
E
K
P
K
V
Site 102
T634
F
V
E
K
P
K
V
T
P
N
P
D
L
L
D
Site 103
S685
P
A
P
R
D
R
A
S
P
A
A
A
E
E
V
Site 104
S698
E
V
V
P
E
W
A
S
C
L
K
S
P
R
I
Site 105
S702
E
W
A
S
C
L
K
S
P
R
I
Q
A
K
P
Site 106
S718
P
K
P
N
Q
N
L
S
E
A
S
G
K
G
A
Site 107
Y728
S
G
K
G
A
E
L
Y
A
R
R
Q
S
R
M
Site 108
S733
E
L
Y
A
R
R
Q
S
R
M
E
K
Y
V
I
Site 109
Y738
R
Q
S
R
M
E
K
Y
V
I
E
S
S
S
H
Site 110
S742
M
E
K
Y
V
I
E
S
S
S
H
T
P
E
L
Site 111
S744
K
Y
V
I
E
S
S
S
H
T
P
E
L
A
R
Site 112
T746
V
I
E
S
S
S
H
T
P
E
L
A
R
C
P
Site 113
S754
P
E
L
A
R
C
P
S
P
T
M
S
L
P
S
Site 114
T756
L
A
R
C
P
S
P
T
M
S
L
P
S
S
W
Site 115
S758
R
C
P
S
P
T
M
S
L
P
S
S
W
K
Y
Site 116
S761
S
P
T
M
S
L
P
S
S
W
K
Y
P
T
N
Site 117
S762
P
T
M
S
L
P
S
S
W
K
Y
P
T
N
A
Site 118
Y765
S
L
P
S
S
W
K
Y
P
T
N
A
P
G
A
Site 119
T767
P
S
S
W
K
Y
P
T
N
A
P
G
A
F
R
Site 120
S777
P
G
A
F
R
V
A
S
R
S
P
A
R
T
P
Site 121
S779
A
F
R
V
A
S
R
S
P
A
R
T
P
P
A
Site 122
T783
A
S
R
S
P
A
R
T
P
P
A
S
L
Y
H
Site 123
S787
P
A
R
T
P
P
A
S
L
Y
H
G
Y
L
P
Site 124
Y789
R
T
P
P
A
S
L
Y
H
G
Y
L
P
E
N
Site 125
Y792
P
A
S
L
Y
H
G
Y
L
P
E
N
G
V
L
Site 126
T804
G
V
L
R
P
E
P
T
K
Q
P
P
Y
Q
L
Site 127
Y809
E
P
T
K
Q
P
P
Y
Q
L
R
P
S
L
F
Site 128
S814
P
P
Y
Q
L
R
P
S
L
F
V
L
S
P
I
Site 129
S819
R
P
S
L
F
V
L
S
P
I
K
E
P
A
K
Site 130
S828
I
K
E
P
A
K
V
S
P
R
A
A
S
P
A
Site 131
S833
K
V
S
P
R
A
A
S
P
A
K
P
S
S
L
Site 132
S838
A
A
S
P
A
K
P
S
S
L
D
L
V
P
N
Site 133
S839
A
S
P
A
K
P
S
S
L
D
L
V
P
N
L
Site 134
S854
P
K
G
A
L
P
P
S
P
A
L
P
R
P
S
Site 135
S861
S
P
A
L
P
R
P
S
R
S
S
P
G
L
Y
Site 136
S863
A
L
P
R
P
S
R
S
S
P
G
L
Y
T
S
Site 137
S864
L
P
R
P
S
R
S
S
P
G
L
Y
T
S
P
Site 138
Y868
S
R
S
S
P
G
L
Y
T
S
P
G
Q
D
S
Site 139
T869
R
S
S
P
G
L
Y
T
S
P
G
Q
D
S
L
Site 140
S870
S
S
P
G
L
Y
T
S
P
G
Q
D
S
L
Q
Site 141
S875
Y
T
S
P
G
Q
D
S
L
Q
P
T
A
V
S
Site 142
T879
G
Q
D
S
L
Q
P
T
A
V
S
P
P
Y
G
Site 143
S882
S
L
Q
P
T
A
V
S
P
P
Y
G
G
D
I
Site 144
Y885
P
T
A
V
S
P
P
Y
G
G
D
I
S
P
V
Site 145
S890
P
P
Y
G
G
D
I
S
P
V
S
P
S
R
A
Site 146
S893
G
G
D
I
S
P
V
S
P
S
R
A
W
S
P
Site 147
S895
D
I
S
P
V
S
P
S
R
A
W
S
P
R
A
Site 148
S899
V
S
P
S
R
A
W
S
P
R
A
K
Q
A
P
Site 149
S909
A
K
Q
A
P
R
P
S
F
S
T
R
N
A
G
Site 150
S911
Q
A
P
R
P
S
F
S
T
R
N
A
G
I
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation