KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FNBP4
Full Name:
Formin-binding protein 4
Alias:
Formin binding protein 4; Formin-binding protein 30; KIAA1014
Type:
Mass (Da):
110249
Number AA:
1017
UniProt ID:
Q8N3X1
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0015629
GO:0016021
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0004969
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0007186
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
R
R
P
I
L
Q
L
S
P
P
G
P
R
G
S
Site 2
S25
S
P
P
G
P
R
G
S
T
P
G
R
D
P
E
Site 3
T26
P
P
G
P
R
G
S
T
P
G
R
D
P
E
P
Site 4
T37
D
P
E
P
E
P
D
T
E
P
D
S
T
A
A
Site 5
S41
E
P
D
T
E
P
D
S
T
A
A
V
P
S
Q
Site 6
T42
P
D
T
E
P
D
S
T
A
A
V
P
S
Q
P
Site 7
S47
D
S
T
A
A
V
P
S
Q
P
A
P
S
A
A
Site 8
S65
A
V
T
A
A
A
A
S
D
D
S
P
S
E
G
Site 9
S68
A
A
A
A
S
D
D
S
P
S
E
G
K
D
E
Site 10
S70
A
A
S
D
D
S
P
S
E
G
K
D
E
Q
E
Site 11
T95
N
P
P
K
P
V
M
T
T
R
P
T
A
V
K
Site 12
T99
P
V
M
T
T
R
P
T
A
V
K
A
T
G
G
Site 13
S116
L
L
G
A
Y
A
D
S
D
D
D
D
N
D
V
Site 14
S124
D
D
D
D
N
D
V
S
E
K
L
A
Q
S
K
Site 15
S130
V
S
E
K
L
A
Q
S
K
E
T
N
G
N
Q
Site 16
T139
E
T
N
G
N
Q
S
T
D
I
D
S
T
L
A
Site 17
S143
N
Q
S
T
D
I
D
S
T
L
A
N
F
L
A
Site 18
T144
Q
S
T
D
I
D
S
T
L
A
N
F
L
A
E
Site 19
S167
P
A
A
P
V
G
A
S
A
P
P
P
T
P
P
Site 20
T172
G
A
S
A
P
P
P
T
P
P
R
P
E
P
K
Site 21
T183
P
E
P
K
E
A
A
T
S
T
L
S
S
S
T
Site 22
S184
E
P
K
E
A
A
T
S
T
L
S
S
S
T
S
Site 23
T185
P
K
E
A
A
T
S
T
L
S
S
S
T
S
N
Site 24
S187
E
A
A
T
S
T
L
S
S
S
T
S
N
G
T
Site 25
S188
A
A
T
S
T
L
S
S
S
T
S
N
G
T
D
Site 26
S189
A
T
S
T
L
S
S
S
T
S
N
G
T
D
S
Site 27
S191
S
T
L
S
S
S
T
S
N
G
T
D
S
T
Q
Site 28
S196
S
T
S
N
G
T
D
S
T
Q
T
S
G
W
Q
Site 29
T197
T
S
N
G
T
D
S
T
Q
T
S
G
W
Q
Y
Site 30
S200
G
T
D
S
T
Q
T
S
G
W
Q
Y
D
T
Q
Site 31
Y204
T
Q
T
S
G
W
Q
Y
D
T
Q
C
S
L
A
Site 32
T206
T
S
G
W
Q
Y
D
T
Q
C
S
L
A
G
V
Site 33
Y248
V
T
W
E
L
P
Q
Y
L
A
T
Q
V
Q
G
Site 34
Y259
Q
V
Q
G
L
Q
H
Y
Q
P
S
S
V
P
G
Site 35
S263
L
Q
H
Y
Q
P
S
S
V
P
G
A
E
T
S
Site 36
Y278
F
V
V
N
T
D
I
Y
S
K
E
K
T
I
S
Site 37
S279
V
V
N
T
D
I
Y
S
K
E
K
T
I
S
V
Site 38
T283
D
I
Y
S
K
E
K
T
I
S
V
S
S
S
K
Site 39
S285
Y
S
K
E
K
T
I
S
V
S
S
S
K
S
G
Site 40
S287
K
E
K
T
I
S
V
S
S
S
K
S
G
P
V
Site 41
S291
I
S
V
S
S
S
K
S
G
P
V
I
A
K
R
Site 42
S312
N
E
G
I
Q
A
L
S
N
S
E
E
E
K
K
Site 43
S314
G
I
Q
A
L
S
N
S
E
E
E
K
K
G
V
Site 44
S324
E
K
K
G
V
A
A
S
L
L
A
P
L
L
P
Site 45
S353
I
C
K
E
E
P
V
S
E
V
K
E
T
S
T
Site 46
T361
E
V
K
E
T
S
T
T
V
E
E
A
T
T
I
Site 47
T367
T
T
V
E
E
A
T
T
I
V
K
P
Q
E
I
Site 48
S383
L
D
N
I
E
D
P
S
Q
E
D
L
C
S
V
Site 49
S389
P
S
Q
E
D
L
C
S
V
V
Q
S
G
E
S
Site 50
S393
D
L
C
S
V
V
Q
S
G
E
S
E
E
E
E
Site 51
T404
E
E
E
E
E
Q
D
T
L
E
L
E
L
V
L
Site 52
S427
A
L
E
E
G
D
G
S
V
S
G
S
S
P
R
Site 53
S429
E
E
G
D
G
S
V
S
G
S
S
P
R
S
D
Site 54
S431
G
D
G
S
V
S
G
S
S
P
R
S
D
I
S
Site 55
S432
D
G
S
V
S
G
S
S
P
R
S
D
I
S
Q
Site 56
S435
V
S
G
S
S
P
R
S
D
I
S
Q
P
A
S
Site 57
S438
S
S
P
R
S
D
I
S
Q
P
A
S
Q
D
G
Site 58
S442
S
D
I
S
Q
P
A
S
Q
D
G
M
R
R
L
Site 59
S451
D
G
M
R
R
L
M
S
K
R
G
K
W
K
M
Site 60
T463
W
K
M
F
V
R
A
T
S
P
E
S
T
S
R
Site 61
S464
K
M
F
V
R
A
T
S
P
E
S
T
S
R
S
Site 62
S467
V
R
A
T
S
P
E
S
T
S
R
S
S
S
K
Site 63
T468
R
A
T
S
P
E
S
T
S
R
S
S
S
K
T
Site 64
S469
A
T
S
P
E
S
T
S
R
S
S
S
K
T
G
Site 65
S471
S
P
E
S
T
S
R
S
S
S
K
T
G
R
D
Site 66
S472
P
E
S
T
S
R
S
S
S
K
T
G
R
D
T
Site 67
S473
E
S
T
S
R
S
S
S
K
T
G
R
D
T
P
Site 68
T475
T
S
R
S
S
S
K
T
G
R
D
T
P
E
N
Site 69
T479
S
S
K
T
G
R
D
T
P
E
N
G
E
T
A
Site 70
T485
D
T
P
E
N
G
E
T
A
I
G
A
E
N
S
Site 71
S499
S
E
K
I
D
E
N
S
D
K
E
M
E
V
E
Site 72
S508
K
E
M
E
V
E
E
S
P
E
K
I
K
V
Q
Site 73
T516
P
E
K
I
K
V
Q
T
T
P
K
V
E
E
E
Site 74
T517
E
K
I
K
V
Q
T
T
P
K
V
E
E
E
Q
Site 75
T536
Q
I
G
E
L
A
N
T
L
T
S
K
F
E
F
Site 76
Y577
E
G
A
L
N
G
N
Y
L
K
R
K
L
Q
D
Site 77
Y592
A
A
E
Q
L
K
Q
Y
E
I
N
A
T
P
K
Site 78
Y612
W
D
R
D
H
R
R
Y
F
Y
V
N
E
Q
S
Site 79
Y614
R
D
H
R
R
Y
F
Y
V
N
E
Q
S
G
E
Site 80
S622
V
N
E
Q
S
G
E
S
Q
W
E
F
P
D
G
Site 81
S636
G
E
E
E
E
E
E
S
Q
A
Q
E
N
R
D
Site 82
T645
A
Q
E
N
R
D
E
T
L
A
K
Q
T
L
K
Site 83
T655
K
Q
T
L
K
D
K
T
G
T
D
S
N
S
T
Site 84
T657
T
L
K
D
K
T
G
T
D
S
N
S
T
E
S
Site 85
S659
K
D
K
T
G
T
D
S
N
S
T
E
S
S
E
Site 86
S661
K
T
G
T
D
S
N
S
T
E
S
S
E
T
S
Site 87
S664
T
D
S
N
S
T
E
S
S
E
T
S
T
G
S
Site 88
S665
D
S
N
S
T
E
S
S
E
T
S
T
G
S
L
Site 89
T667
N
S
T
E
S
S
E
T
S
T
G
S
L
C
K
Site 90
S668
S
T
E
S
S
E
T
S
T
G
S
L
C
K
E
Site 91
T669
T
E
S
S
E
T
S
T
G
S
L
C
K
E
S
Site 92
S671
S
S
E
T
S
T
G
S
L
C
K
E
S
F
S
Site 93
S676
T
G
S
L
C
K
E
S
F
S
G
Q
V
S
S
Site 94
S678
S
L
C
K
E
S
F
S
G
Q
V
S
S
S
S
Site 95
S682
E
S
F
S
G
Q
V
S
S
S
S
L
M
P
L
Site 96
S721
P
P
P
P
P
P
E
S
P
P
P
P
P
P
P
Site 97
S747
V
E
M
E
D
E
G
S
E
E
P
P
A
P
G
Site 98
T755
E
E
P
P
A
P
G
T
E
E
D
T
P
L
K
Site 99
T759
A
P
G
T
E
E
D
T
P
L
K
P
S
A
Q
Site 100
T768
L
K
P
S
A
Q
T
T
V
V
T
S
Q
S
S
Site 101
S772
A
Q
T
T
V
V
T
S
Q
S
S
V
D
S
T
Site 102
S774
T
T
V
V
T
S
Q
S
S
V
D
S
T
I
S
Site 103
S775
T
V
V
T
S
Q
S
S
V
D
S
T
I
S
S
Site 104
S778
T
S
Q
S
S
V
D
S
T
I
S
S
S
S
S
Site 105
T779
S
Q
S
S
V
D
S
T
I
S
S
S
S
S
T
Site 106
S781
S
S
V
D
S
T
I
S
S
S
S
S
T
K
G
Site 107
S782
S
V
D
S
T
I
S
S
S
S
S
T
K
G
I
Site 108
S783
V
D
S
T
I
S
S
S
S
S
T
K
G
I
K
Site 109
S785
S
T
I
S
S
S
S
S
T
K
G
I
K
R
K
Site 110
T794
K
G
I
K
R
K
A
T
E
I
S
T
A
V
V
Site 111
S804
S
T
A
V
V
Q
R
S
A
T
I
G
S
S
P
Site 112
S810
R
S
A
T
I
G
S
S
P
V
L
Y
S
Q
S
Site 113
S817
S
P
V
L
Y
S
Q
S
A
I
A
T
G
H
Q
Site 114
S857
G
H
Q
A
R
G
M
S
L
Q
S
N
Y
L
G
Site 115
T901
R
G
A
V
P
T
A
T
I
I
E
P
P
P
P
Site 116
S939
R
K
D
K
A
K
K
S
K
T
K
M
P
S
L
Site 117
T941
D
K
A
K
K
S
K
T
K
M
P
S
L
V
K
Site 118
S945
K
S
K
T
K
M
P
S
L
V
K
K
W
Q
S
Site 119
S952
S
L
V
K
K
W
Q
S
I
Q
R
E
L
D
E
Site 120
S963
E
L
D
E
E
D
N
S
S
S
S
E
E
D
R
Site 121
S964
L
D
E
E
D
N
S
S
S
S
E
E
D
R
E
Site 122
S965
D
E
E
D
N
S
S
S
S
E
E
D
R
E
S
Site 123
S966
E
E
D
N
S
S
S
S
E
E
D
R
E
S
T
Site 124
S972
S
S
E
E
D
R
E
S
T
A
Q
K
R
I
E
Site 125
T973
S
E
E
D
R
E
S
T
A
Q
K
R
I
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation