KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
PRSS35
Full Name:
Inactive serine protease 35
Alias:
Type:
Mass (Da):
47098
Number AA:
413
UniProt ID:
Q8N3Z0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S39
R
K
V
P
R
I
V
S
E
R
T
F
H
L
T
Site 2
T42
P
R
I
V
S
E
R
T
F
H
L
T
S
P
A
Site 3
T46
S
E
R
T
F
H
L
T
S
P
A
F
E
A
D
Site 4
S47
E
R
T
F
H
L
T
S
P
A
F
E
A
D
A
Site 5
T72
E
C
Q
K
E
L
P
T
P
S
L
S
E
L
E
Site 6
S74
Q
K
E
L
P
T
P
S
L
S
E
L
E
D
Y
Site 7
S76
E
L
P
T
P
S
L
S
E
L
E
D
Y
L
S
Site 8
Y81
S
L
S
E
L
E
D
Y
L
S
Y
E
T
V
F
Site 9
S83
S
E
L
E
D
Y
L
S
Y
E
T
V
F
E
N
Site 10
Y84
E
L
E
D
Y
L
S
Y
E
T
V
F
E
N
G
Site 11
T86
E
D
Y
L
S
Y
E
T
V
F
E
N
G
T
R
Site 12
T96
E
N
G
T
R
T
L
T
R
V
K
V
Q
D
L
Site 13
S117
N
I
T
T
K
G
V
S
V
R
R
K
R
Q
V
Site 14
Y125
V
R
R
K
R
Q
V
Y
G
T
D
S
R
F
S
Site 15
T127
R
K
R
Q
V
Y
G
T
D
S
R
F
S
I
L
Site 16
S129
R
Q
V
Y
G
T
D
S
R
F
S
I
L
D
K
Site 17
S132
Y
G
T
D
S
R
F
S
I
L
D
K
R
F
L
Site 18
Y177
C
V
H
D
G
K
D
Y
V
K
G
S
K
K
L
Site 19
S195
L
L
K
M
R
N
K
S
G
G
K
K
R
R
G
Site 20
S203
G
G
K
K
R
R
G
S
K
R
S
R
R
E
A
Site 21
S206
K
R
R
G
S
K
R
S
R
R
E
A
S
G
G
Site 22
S211
K
R
S
R
R
E
A
S
G
G
D
Q
R
E
G
Site 23
T219
G
G
D
Q
R
E
G
T
R
E
H
L
R
E
R
Site 24
S236
G
G
R
R
R
K
K
S
G
R
G
Q
R
I
A
Site 25
S248
R
I
A
E
G
R
P
S
F
Q
W
T
R
V
K
Site 26
T252
G
R
P
S
F
Q
W
T
R
V
K
N
T
H
I
Site 27
T272
R
G
G
M
G
D
A
T
L
D
Y
D
Y
A
L
Site 28
Y277
D
A
T
L
D
Y
D
Y
A
L
L
E
L
K
R
Site 29
Y290
K
R
A
H
K
K
K
Y
M
E
L
G
I
S
P
Site 30
S296
K
Y
M
E
L
G
I
S
P
T
I
K
K
M
P
Site 31
T298
M
E
L
G
I
S
P
T
I
K
K
M
P
G
G
Site 32
S310
P
G
G
M
I
H
F
S
G
F
D
N
D
R
A
Site 33
Y322
D
R
A
D
Q
L
V
Y
R
F
C
S
V
S
D
Site 34
S326
Q
L
V
Y
R
F
C
S
V
S
D
E
S
N
D
Site 35
S328
V
Y
R
F
C
S
V
S
D
E
S
N
D
L
L
Site 36
Y336
D
E
S
N
D
L
L
Y
Q
Y
C
D
A
E
S
Site 37
Y338
S
N
D
L
L
Y
Q
Y
C
D
A
E
S
G
S
Site 38
S343
Y
Q
Y
C
D
A
E
S
G
S
T
G
S
G
V
Site 39
S345
Y
C
D
A
E
S
G
S
T
G
S
G
V
Y
L
Site 40
Y351
G
S
T
G
S
G
V
Y
L
R
L
K
D
P
D
Site 41
Y385
V
H
G
V
Q
K
D
Y
N
V
A
V
R
I
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation