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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RASGEF1C
Full Name:
Ras-GEF domain-containing family member 1C
Alias:
FLJ35841; Rasgef domain family, member 1c; Rasgef1c; Rasgef1c protein; Rgf1c
Type:
Mass (Da):
52870
Number AA:
466
UniProt ID:
Q8N431
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005085
PhosphoSite+
KinaseNET
Biological Process:
GO:0051056
GO:0007264
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T4
_
_
_
_
M
P
Q
T
L
S
A
S
D
M
V
Site 2
S6
_
_
M
P
Q
T
L
S
A
S
D
M
V
T
P
Site 3
S8
M
P
Q
T
L
S
A
S
D
M
V
T
P
G
S
Site 4
T12
L
S
A
S
D
M
V
T
P
G
S
L
S
P
P
Site 5
S15
S
D
M
V
T
P
G
S
L
S
P
P
P
T
E
Site 6
S17
M
V
T
P
G
S
L
S
P
P
P
T
E
P
T
Site 7
T21
G
S
L
S
P
P
P
T
E
P
T
D
G
E
Q
Site 8
S42
D
G
A
P
S
S
A
S
L
E
T
L
I
Q
H
Site 9
Y56
H
L
V
P
T
A
D
Y
Y
P
E
K
A
Y
I
Site 10
Y57
L
V
P
T
A
D
Y
Y
P
E
K
A
Y
I
F
Site 11
T120
L
L
A
E
W
T
E
T
F
P
R
D
F
Q
E
Site 12
Y148
I
A
P
C
D
E
A
Y
R
K
R
M
H
Q
L
Site 13
S181
V
G
A
D
K
P
I
S
Y
R
T
K
P
P
A
Site 14
T184
D
K
P
I
S
Y
R
T
K
P
P
A
S
I
H
Site 15
S189
Y
R
T
K
P
P
A
S
I
H
R
E
L
L
G
Site 16
S199
R
E
L
L
G
V
C
S
D
P
Y
T
L
A
Q
Site 17
T203
G
V
C
S
D
P
Y
T
L
A
Q
Q
L
T
H
Site 18
S236
V
N
K
D
P
L
A
S
T
K
P
C
F
S
D
Site 19
S242
A
S
T
K
P
C
F
S
D
K
T
S
N
L
E
Site 20
T245
K
P
C
F
S
D
K
T
S
N
L
E
A
Y
V
Site 21
S246
P
C
F
S
D
K
T
S
N
L
E
A
Y
V
K
Site 22
Y251
K
T
S
N
L
E
A
Y
V
K
W
F
N
R
L
Site 23
S308
I
I
S
G
M
N
M
S
P
V
S
R
L
K
K
Site 24
S311
G
M
N
M
S
P
V
S
R
L
K
K
T
W
A
Site 25
T316
P
V
S
R
L
K
K
T
W
A
K
V
R
T
A
Site 26
Y341
P
T
G
N
F
C
N
Y
R
T
A
L
R
G
A
Site 27
S352
L
R
G
A
A
H
R
S
L
T
A
H
S
S
R
Site 28
T354
G
A
A
H
R
S
L
T
A
H
S
S
R
E
K
Site 29
S357
H
R
S
L
T
A
H
S
S
R
E
K
I
V
I
Site 30
S358
R
S
L
T
A
H
S
S
R
E
K
I
V
I
P
Site 31
T427
S
I
T
H
Y
L
Y
T
A
P
I
F
S
E
D
Site 32
Y437
I
F
S
E
D
G
L
Y
L
A
S
Y
E
S
E
Site 33
S440
E
D
G
L
Y
L
A
S
Y
E
S
E
S
P
E
Site 34
Y441
D
G
L
Y
L
A
S
Y
E
S
E
S
P
E
N
Site 35
S443
L
Y
L
A
S
Y
E
S
E
S
P
E
N
Q
T
Site 36
S445
L
A
S
Y
E
S
E
S
P
E
N
Q
T
E
K
Site 37
S461
R
W
K
A
L
R
S
S
I
L
G
K
T
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation