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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GUF1
Full Name:
Translation factor GUF1, mitochondrial
Alias:
Elongation factor 4 homolog;GTPase GUF1;Ribosomal back-translocase
Type:
Mass (Da):
74328
Number AA:
669
UniProt ID:
Q8N442
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T35
P
G
P
R
S
A
P
T
L
G
A
A
P
E
S
Site 2
S42
T
L
G
A
A
P
E
S
W
A
T
D
R
L
Y
Site 3
T45
A
A
P
E
S
W
A
T
D
R
L
Y
S
S
A
Site 4
Y49
S
W
A
T
D
R
L
Y
S
S
A
E
F
K
E
Site 5
S50
W
A
T
D
R
L
Y
S
S
A
E
F
K
E
K
Site 6
S51
A
T
D
R
L
Y
S
S
A
E
F
K
E
K
L
Site 7
S61
F
K
E
K
L
D
M
S
R
F
P
V
E
N
I
Site 8
T92
A
D
R
L
L
E
L
T
G
T
I
D
K
T
K
Site 9
T94
R
L
L
E
L
T
G
T
I
D
K
T
K
N
N
Site 10
T98
L
T
G
T
I
D
K
T
K
N
N
K
Q
V
L
Site 11
T117
V
E
R
E
R
G
I
T
V
K
A
Q
T
A
S
Site 12
Y134
Y
N
C
E
G
K
Q
Y
L
L
N
L
I
D
T
Site 13
S148
T
P
G
H
V
D
F
S
Y
E
V
S
R
S
L
Site 14
Y149
P
G
H
V
D
F
S
Y
E
V
S
R
S
L
S
Site 15
S152
V
D
F
S
Y
E
V
S
R
S
L
S
A
C
Q
Site 16
S154
F
S
Y
E
V
S
R
S
L
S
A
C
Q
G
V
Site 17
S218
E
K
V
F
D
I
P
S
D
E
C
I
K
I
S
Site 18
S261
L
R
A
L
V
F
D
S
T
F
D
Q
Y
R
G
Site 19
T262
R
A
L
V
F
D
S
T
F
D
Q
Y
R
G
V
Site 20
Y266
F
D
S
T
F
D
Q
Y
R
G
V
I
A
N
V
Site 21
S288
S
K
G
D
K
I
V
S
A
H
T
Q
K
T
Y
Site 22
Y295
S
A
H
T
Q
K
T
Y
E
V
N
E
V
G
V
Site 23
Y314
E
Q
P
T
H
K
L
Y
A
G
Q
V
G
Y
L
Site 24
T329
I
A
G
M
K
D
V
T
E
A
Q
I
G
D
T
Site 25
Y362
P
M
V
F
A
G
M
Y
P
L
D
Q
S
E
Y
Site 26
S367
G
M
Y
P
L
D
Q
S
E
Y
N
N
L
K
S
Site 27
Y369
Y
P
L
D
Q
S
E
Y
N
N
L
K
S
A
I
Site 28
S374
S
E
Y
N
N
L
K
S
A
I
E
K
L
T
L
Site 29
T380
K
S
A
I
E
K
L
T
L
N
D
S
S
V
T
Site 30
S384
E
K
L
T
L
N
D
S
S
V
T
V
H
R
D
Site 31
S385
K
L
T
L
N
D
S
S
V
T
V
H
R
D
S
Site 32
T387
T
L
N
D
S
S
V
T
V
H
R
D
S
S
L
Site 33
Y421
N
Q
R
L
E
Q
E
Y
N
A
S
V
I
L
T
Site 34
S424
L
E
Q
E
Y
N
A
S
V
I
L
T
T
P
T
Site 35
S439
V
P
Y
K
A
V
L
S
S
S
K
L
I
K
E
Site 36
S441
Y
K
A
V
L
S
S
S
K
L
I
K
E
H
R
Site 37
T453
E
H
R
E
K
E
I
T
I
I
N
P
A
Q
F
Site 38
S464
P
A
Q
F
P
D
K
S
K
V
T
E
Y
L
E
Site 39
Y469
D
K
S
K
V
T
E
Y
L
E
P
V
V
L
G
Site 40
T477
L
E
P
V
V
L
G
T
I
I
T
P
D
E
Y
Site 41
Y514
Q
N
R
V
M
L
K
Y
L
F
P
L
N
E
I
Site 42
Y526
N
E
I
V
V
D
F
Y
D
S
L
K
S
L
S
Site 43
S531
D
F
Y
D
S
L
K
S
L
S
S
G
Y
A
S
Site 44
S533
Y
D
S
L
K
S
L
S
S
G
Y
A
S
F
D
Site 45
S534
D
S
L
K
S
L
S
S
G
Y
A
S
F
D
Y
Site 46
S538
S
L
S
S
G
Y
A
S
F
D
Y
E
D
A
G
Site 47
Y541
S
G
Y
A
S
F
D
Y
E
D
A
G
Y
Q
T
Site 48
Y546
F
D
Y
E
D
A
G
Y
Q
T
A
E
L
V
K
Site 49
T568
N
T
V
E
E
L
V
T
V
V
H
K
D
K
A
Site 50
S589
I
C
E
R
L
K
D
S
L
P
R
Q
L
F
E
Site 51
T612
S
K
I
I
A
R
E
T
V
K
A
Y
R
K
N
Site 52
T630
K
C
Y
G
G
D
I
T
R
K
M
K
L
L
K
Site 53
T665
A
F
I
K
V
L
K
T
Q
S
S
K
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation