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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KLHL36
Full Name:
Kelch-like protein 36
Alias:
Type:
Mass (Da):
69896
Number AA:
616
UniProt ID:
Q8N4N3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
M
E
G
S
R
Q
T
R
V
S
R
P
Y
K
Site 2
S11
G
S
R
Q
T
R
V
S
R
P
Y
K
I
S
E
Site 3
Y14
Q
T
R
V
S
R
P
Y
K
I
S
E
S
S
K
Site 4
S17
V
S
R
P
Y
K
I
S
E
S
S
K
V
Y
R
Site 5
S19
R
P
Y
K
I
S
E
S
S
K
V
Y
R
W
A
Site 6
Y23
I
S
E
S
S
K
V
Y
R
W
A
D
H
S
S
Site 7
S29
V
Y
R
W
A
D
H
S
S
T
V
L
Q
R
L
Site 8
S30
Y
R
W
A
D
H
S
S
T
V
L
Q
R
L
N
Site 9
T31
R
W
A
D
H
S
S
T
V
L
Q
R
L
N
E
Site 10
Y138
V
V
D
F
C
C
E
Y
L
E
Q
E
V
S
E
Site 11
S144
E
Y
L
E
Q
E
V
S
E
D
N
Y
L
Y
L
Site 12
Y148
Q
E
V
S
E
D
N
Y
L
Y
L
Q
E
L
A
Site 13
Y150
V
S
E
D
N
Y
L
Y
L
Q
E
L
A
S
I
Site 14
S159
Q
E
L
A
S
I
Y
S
L
K
R
L
D
A
F
Site 15
Y196
S
M
Q
K
L
C
V
Y
L
S
S
S
E
V
Q
Site 16
S198
Q
K
L
C
V
Y
L
S
S
S
E
V
Q
R
E
Site 17
S200
L
C
V
Y
L
S
S
S
E
V
Q
R
E
C
E
Site 18
T219
Q
A
A
L
Q
W
L
T
Q
Q
P
E
R
E
A
Site 19
Y273
F
I
E
E
A
V
R
Y
H
N
N
L
A
A
Q
Site 20
T292
T
K
R
T
A
L
R
T
N
Q
E
R
L
L
F
Site 21
S312
S
E
R
C
L
E
L
S
D
D
T
C
Y
L
D
Site 22
T315
C
L
E
L
S
D
D
T
C
Y
L
D
A
K
S
Site 23
Y317
E
L
S
D
D
T
C
Y
L
D
A
K
S
E
Q
Site 24
T329
S
E
Q
W
V
K
E
T
P
L
P
A
R
R
S
Site 25
S355
F
I
A
G
G
S
F
S
R
D
N
G
G
D
A
Site 26
Y368
D
A
A
S
N
L
L
Y
R
Y
D
P
R
C
K
Site 27
Y370
A
S
N
L
L
Y
R
Y
D
P
R
C
K
Q
W
Site 28
Y391
N
Q
R
R
V
D
F
Y
L
A
S
I
E
D
M
Site 29
S412
R
N
E
N
G
A
L
S
S
V
E
T
Y
S
P
Site 30
S413
N
E
N
G
A
L
S
S
V
E
T
Y
S
P
K
Site 31
T416
G
A
L
S
S
V
E
T
Y
S
P
K
T
D
S
Site 32
S418
L
S
S
V
E
T
Y
S
P
K
T
D
S
W
S
Site 33
T421
V
E
T
Y
S
P
K
T
D
S
W
S
Y
V
A
Site 34
S423
T
Y
S
P
K
T
D
S
W
S
Y
V
A
G
L
Site 35
S425
S
P
K
T
D
S
W
S
Y
V
A
G
L
P
R
Site 36
Y426
P
K
T
D
S
W
S
Y
V
A
G
L
P
R
F
Site 37
Y435
A
G
L
P
R
F
T
Y
G
H
A
G
T
I
Y
Site 38
T440
F
T
Y
G
H
A
G
T
I
Y
K
D
F
V
Y
Site 39
Y442
Y
G
H
A
G
T
I
Y
K
D
F
V
Y
I
S
Site 40
Y447
T
I
Y
K
D
F
V
Y
I
S
G
G
H
D
Y
Site 41
Y454
Y
I
S
G
G
H
D
Y
Q
I
G
P
Y
R
K
Site 42
Y466
Y
R
K
N
L
L
C
Y
D
H
R
T
D
V
W
Site 43
T480
W
E
E
R
R
P
M
T
T
A
R
G
W
H
S
Site 44
T481
E
E
R
R
P
M
T
T
A
R
G
W
H
S
M
Site 45
S487
T
T
A
R
G
W
H
S
M
C
S
L
G
D
S
Site 46
S490
R
G
W
H
S
M
C
S
L
G
D
S
I
Y
S
Site 47
Y496
C
S
L
G
D
S
I
Y
S
I
G
G
S
D
D
Site 48
S501
S
I
Y
S
I
G
G
S
D
D
N
I
E
S
M
Site 49
S507
G
S
D
D
N
I
E
S
M
E
R
F
D
V
L
Site 50
T559
G
G
Y
S
W
E
N
T
A
F
S
K
T
V
Q
Site 51
Y568
F
S
K
T
V
Q
V
Y
D
R
E
A
D
K
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation