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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBC1D19
Full Name:
TBC1 domain family member 19
Alias:
Type:
Mass (Da):
60268
Number AA:
526
UniProt ID:
Q8N5T2
International Prot ID:
IPI00551003
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005097
PhosphoSite+
KinaseNET
Biological Process:
GO:0032313
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y25
K
L
K
G
S
N
L
Y
S
Q
L
E
R
Q
A
Site 2
S26
L
K
G
S
N
L
Y
S
Q
L
E
R
Q
A
W
Site 3
S35
L
E
R
Q
A
W
A
S
L
Q
R
P
E
I
K
Site 4
Y68
K
K
L
Q
N
A
V
Y
S
E
L
S
V
F
P
Site 5
S78
L
S
V
F
P
L
P
S
H
P
A
A
P
P
E
Site 6
Y93
H
L
K
E
P
L
V
Y
M
R
K
A
Q
G
S
Site 7
S100
Y
M
R
K
A
Q
G
S
W
E
K
R
I
L
K
Site 8
S108
W
E
K
R
I
L
K
S
L
N
S
M
C
T
E
Site 9
S117
N
S
M
C
T
E
L
S
I
P
L
A
R
K
R
Site 10
T141
N
K
W
N
E
M
G
T
D
E
P
D
L
S
L
Site 11
S147
G
T
D
E
P
D
L
S
L
F
R
P
V
Y
A
Site 12
Y170
I
N
L
R
N
P
N
Y
E
N
G
D
S
L
S
Site 13
S175
P
N
Y
E
N
G
D
S
L
S
F
R
T
H
L
Site 14
S177
Y
E
N
G
D
S
L
S
F
R
T
H
L
G
L
Site 15
S216
G
Q
L
G
I
D
D
S
T
Q
V
P
P
E
L
Site 16
T217
Q
L
G
I
D
D
S
T
Q
V
P
P
E
L
F
Site 17
Y247
D
S
A
A
A
Q
Q
Y
I
R
Q
G
S
P
T
Site 18
S252
Q
Q
Y
I
R
Q
G
S
P
T
A
L
R
A
E
Site 19
T254
Y
I
R
Q
G
S
P
T
A
L
R
A
E
L
W
Site 20
Y276
S
Q
P
E
D
V
L
Y
Y
E
Q
L
K
T
N
Site 21
S293
Q
H
D
L
L
V
D
S
L
I
Y
K
D
V
K
Site 22
S304
K
D
V
K
L
T
A
S
N
D
D
Y
Y
F
V
Site 23
Y308
L
T
A
S
N
D
D
Y
Y
F
V
F
E
D
Y
Site 24
Y309
T
A
S
N
D
D
Y
Y
F
V
F
E
D
Y
L
Site 25
S331
S
R
D
T
S
V
L
S
H
F
A
F
N
S
A
Site 26
S337
L
S
H
F
A
F
N
S
A
S
P
P
K
S
Y
Site 27
S339
H
F
A
F
N
S
A
S
P
P
K
S
Y
I
R
Site 28
S343
N
S
A
S
P
P
K
S
Y
I
R
G
K
L
G
Site 29
Y344
S
A
S
P
P
K
S
Y
I
R
G
K
L
G
L
Site 30
Y354
G
K
L
G
L
E
E
Y
A
V
F
Y
P
P
N
Site 31
Y387
Y
H
E
P
S
K
L
Y
Q
I
F
R
E
M
Y
Site 32
S403
R
F
F
F
R
L
H
S
I
S
S
H
P
S
G
Site 33
S406
F
R
L
H
S
I
S
S
H
P
S
G
I
V
S
Site 34
Y431
T
Y
L
P
Q
L
F
Y
H
L
R
E
I
G
A
Site 35
S444
G
A
Q
P
L
R
I
S
F
K
W
M
V
R
A
Site 36
S453
K
W
M
V
R
A
F
S
G
Y
L
A
T
D
Q
Site 37
T510
A
V
L
A
D
L
F
T
L
K
V
M
P
L
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation