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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MSL3L1
Full Name:
Male-specific lethal 3 homolog
Alias:
M3L1_HUMAN; Male-specific lethal 3; Male-specific lethal 3-like 1; Male-specific lethal-3 homolog 1; Male-specific lethal-3 homologue 1; MS3L1; MSL3-like 1
Type:
Transcription protein
Mass (Da):
59824
Number AA:
521
UniProt ID:
Q8N5Y2
International Prot ID:
IPI00297145
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000785
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003682
GO:0003700
GO:0003682
PhosphoSite+
KinaseNET
Biological Process:
GO:0006333
GO:0016568
GO:0007275
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T25
L
C
F
E
P
D
P
T
K
A
R
V
L
Y
D
Site 2
Y52
K
G
R
K
I
P
E
Y
L
I
H
F
N
G
W
Site 3
T76
E
D
H
V
L
R
D
T
D
E
N
R
R
L
Q
Site 4
S96
K
A
V
A
R
L
R
S
T
G
R
K
K
K
R
Site 5
T97
A
V
A
R
L
R
S
T
G
R
K
K
K
R
C
Site 6
T118
S
V
L
K
G
L
P
T
E
E
K
D
E
N
D
Site 7
S128
K
D
E
N
D
E
N
S
L
S
S
S
S
D
C
Site 8
S130
E
N
D
E
N
S
L
S
S
S
S
D
C
S
E
Site 9
S131
N
D
E
N
S
L
S
S
S
S
D
C
S
E
N
Site 10
S132
D
E
N
S
L
S
S
S
S
D
C
S
E
N
K
Site 11
S133
E
N
S
L
S
S
S
S
D
C
S
E
N
K
D
Site 12
S136
L
S
S
S
S
D
C
S
E
N
K
D
E
E
I
Site 13
S144
E
N
K
D
E
E
I
S
E
E
S
D
I
E
E
Site 14
S147
D
E
E
I
S
E
E
S
D
I
E
E
K
T
E
Site 15
T173
E
M
E
E
R
T
I
T
I
E
I
P
E
V
L
Site 16
Y189
K
Q
L
E
D
D
C
Y
Y
I
N
R
R
K
R
Site 17
Y190
Q
L
E
D
D
C
Y
Y
I
N
R
R
K
R
L
Site 18
S224
F
A
I
N
A
A
F
S
A
N
E
R
P
R
H
Site 19
Y277
P
L
V
L
L
Y
P
Y
E
Q
A
Q
Y
K
K
Site 20
Y282
Y
P
Y
E
Q
A
Q
Y
K
K
V
T
S
S
K
Site 21
S287
A
Q
Y
K
K
V
T
S
S
K
F
F
L
P
I
Site 22
S288
Q
Y
K
K
V
T
S
S
K
F
F
L
P
I
K
Site 23
S297
F
F
L
P
I
K
E
S
A
T
S
T
N
R
S
Site 24
S300
P
I
K
E
S
A
T
S
T
N
R
S
Q
E
E
Site 25
T301
I
K
E
S
A
T
S
T
N
R
S
Q
E
E
L
Site 26
S304
S
A
T
S
T
N
R
S
Q
E
E
L
S
P
S
Site 27
S309
N
R
S
Q
E
E
L
S
P
S
P
P
L
L
N
Site 28
S311
S
Q
E
E
L
S
P
S
P
P
L
L
N
P
S
Site 29
S318
S
P
P
L
L
N
P
S
T
P
Q
S
T
E
S
Site 30
T319
P
P
L
L
N
P
S
T
P
Q
S
T
E
S
Q
Site 31
S322
L
N
P
S
T
P
Q
S
T
E
S
Q
P
T
T
Site 32
T323
N
P
S
T
P
Q
S
T
E
S
Q
P
T
T
G
Site 33
S325
S
T
P
Q
S
T
E
S
Q
P
T
T
G
E
P
Site 34
T328
Q
S
T
E
S
Q
P
T
T
G
E
P
A
T
P
Site 35
T329
S
T
E
S
Q
P
T
T
G
E
P
A
T
P
K
Site 36
T334
P
T
T
G
E
P
A
T
P
K
R
R
K
A
E
Site 37
S347
A
E
P
E
A
L
Q
S
L
R
R
S
T
R
H
Site 38
S351
A
L
Q
S
L
R
R
S
T
R
H
S
A
N
C
Site 39
T352
L
Q
S
L
R
R
S
T
R
H
S
A
N
C
D
Site 40
S355
L
R
R
S
T
R
H
S
A
N
C
D
R
L
S
Site 41
S362
S
A
N
C
D
R
L
S
E
S
S
A
S
P
Q
Site 42
S364
N
C
D
R
L
S
E
S
S
A
S
P
Q
P
K
Site 43
S365
C
D
R
L
S
E
S
S
A
S
P
Q
P
K
R
Site 44
S367
R
L
S
E
S
S
A
S
P
Q
P
K
R
R
Q
Site 45
T377
P
K
R
R
Q
Q
D
T
S
A
S
M
P
K
L
Site 46
S378
K
R
R
Q
Q
D
T
S
A
S
M
P
K
L
F
Site 47
S380
R
Q
Q
D
T
S
A
S
M
P
K
L
F
L
H
Site 48
T392
F
L
H
L
E
K
K
T
P
V
H
S
R
S
S
Site 49
S396
E
K
K
T
P
V
H
S
R
S
S
S
P
I
P
Site 50
S398
K
T
P
V
H
S
R
S
S
S
P
I
P
L
T
Site 51
S399
T
P
V
H
S
R
S
S
S
P
I
P
L
T
P
Site 52
S400
P
V
H
S
R
S
S
S
P
I
P
L
T
P
S
Site 53
T405
S
S
S
P
I
P
L
T
P
S
K
E
G
S
A
Site 54
S407
S
P
I
P
L
T
P
S
K
E
G
S
A
V
F
Site 55
S411
L
T
P
S
K
E
G
S
A
V
F
A
G
F
E
Site 56
T422
A
G
F
E
G
R
R
T
N
E
I
N
E
V
L
Site 57
Y438
W
K
L
V
P
D
N
Y
P
P
G
D
Q
P
P
Site 58
S448
G
D
Q
P
P
P
P
S
Y
I
Y
G
A
Q
H
Site 59
Y449
D
Q
P
P
P
P
S
Y
I
Y
G
A
Q
H
L
Site 60
Y451
P
P
P
P
S
Y
I
Y
G
A
Q
H
L
L
R
Site 61
S471
P
E
I
L
G
K
M
S
F
S
E
K
N
L
K
Site 62
S473
I
L
G
K
M
S
F
S
E
K
N
L
K
A
L
Site 63
Y494
F
L
R
F
L
A
E
Y
H
D
D
F
F
P
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation