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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PARP16
Full Name:
Poly [ADP-ribose] polymerase 16
Alias:
Type:
Mass (Da):
36383
Number AA:
322
UniProt ID:
Q8N5Y8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S29
L
R
C
S
L
F
A
S
A
L
Q
S
Y
K
R
Site 2
S33
L
F
A
S
A
L
Q
S
Y
K
R
D
S
V
L
Site 3
Y34
F
A
S
A
L
Q
S
Y
K
R
D
S
V
L
R
Site 4
S38
L
Q
S
Y
K
R
D
S
V
L
R
P
F
P
A
Site 5
S46
V
L
R
P
F
P
A
S
Y
A
R
G
D
C
K
Site 6
Y47
L
R
P
F
P
A
S
Y
A
R
G
D
C
K
D
Site 7
S63
E
A
L
L
A
D
A
S
K
L
P
N
L
K
E
Site 8
S74
N
L
K
E
L
L
Q
S
S
G
D
N
H
K
R
Site 9
S87
K
R
A
W
D
L
V
S
W
I
L
S
S
K
V
Site 10
T112
F
E
K
I
Q
K
L
T
G
A
P
H
T
P
V
Site 11
T117
K
L
T
G
A
P
H
T
P
V
P
A
P
D
F
Site 12
Y130
D
F
L
F
E
I
E
Y
F
D
P
A
N
A
K
Site 13
Y139
D
P
A
N
A
K
F
Y
E
T
K
G
E
R
D
Site 14
Y149
K
G
E
R
D
L
I
Y
A
F
H
G
S
R
L
Site 15
S154
L
I
Y
A
F
H
G
S
R
L
E
N
F
H
S
Site 16
S161
S
R
L
E
N
F
H
S
I
I
H
N
G
L
H
Site 17
T181
T
S
L
F
G
E
G
T
Y
L
T
S
D
L
S
Site 18
Y193
D
L
S
L
A
L
I
Y
S
P
H
G
H
G
W
Site 19
S194
L
S
L
A
L
I
Y
S
P
H
G
H
G
W
Q
Site 20
S203
H
G
H
G
W
Q
H
S
L
L
G
P
I
L
S
Site 21
S232
C
Q
T
K
K
K
D
S
K
E
I
D
R
R
R
Site 22
Y254
G
G
D
I
P
P
K
Y
F
V
V
T
N
N
Q
Site 23
Y267
N
Q
L
L
R
V
K
Y
L
L
V
Y
S
Q
K
Site 24
Y271
R
V
K
Y
L
L
V
Y
S
Q
K
P
P
K
R
Site 25
S272
V
K
Y
L
L
V
Y
S
Q
K
P
P
K
R
A
Site 26
S280
Q
K
P
P
K
R
A
S
S
Q
L
S
W
F
S
Site 27
S281
K
P
P
K
R
A
S
S
Q
L
S
W
F
S
S
Site 28
S284
K
R
A
S
S
Q
L
S
W
F
S
S
H
W
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation