KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
LZTR1
Full Name:
Leucine-zipper-like transcriptional regulator 1
Alias:
Type:
Mass (Da):
94719
Number AA:
840
UniProt ID:
Q8N653
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
A
R
S
K
V
A
P
S
V
D
F
D
H
S
C
Site 2
S33
P
S
V
D
F
D
H
S
C
S
D
S
V
E
Y
Site 3
S35
V
D
F
D
H
S
C
S
D
S
V
E
Y
L
T
Site 4
S37
F
D
H
S
C
S
D
S
V
E
Y
L
T
L
N
Site 5
Y40
S
C
S
D
S
V
E
Y
L
T
L
N
F
G
P
Site 6
T42
S
D
S
V
E
Y
L
T
L
N
F
G
P
F
E
Site 7
S69
E
F
V
G
A
R
R
S
K
H
T
V
V
A
Y
Site 8
T72
G
A
R
R
S
K
H
T
V
V
A
Y
K
D
A
Site 9
T90
F
G
G
D
N
G
K
T
M
L
N
D
L
L
R
Site 10
T110
C
S
W
C
R
A
F
T
T
G
T
P
P
A
P
Site 11
T111
S
W
C
R
A
F
T
T
G
T
P
P
A
P
R
Site 12
T113
C
R
A
F
T
T
G
T
P
P
A
P
R
Y
H
Site 13
Y119
G
T
P
P
A
P
R
Y
H
H
S
A
V
V
Y
Site 14
S122
P
A
P
R
Y
H
H
S
A
V
V
Y
G
S
S
Site 15
Y141
G
G
Y
T
G
D
I
Y
S
N
S
N
L
K
N
Site 16
S142
G
Y
T
G
D
I
Y
S
N
S
N
L
K
N
K
Site 17
Y155
N
K
N
D
L
F
E
Y
K
F
A
T
G
Q
W
Site 18
S176
G
R
L
P
V
A
R
S
A
H
G
A
T
V
Y
Site 19
T204
A
R
L
N
D
M
W
T
I
G
L
Q
D
R
E
Site 20
T213
G
L
Q
D
R
E
L
T
C
W
E
E
V
A
Q
Site 21
S227
Q
S
G
E
I
P
P
S
C
C
N
F
P
V
A
Site 22
S244
R
D
K
M
F
V
F
S
G
Q
S
G
A
K
I
Site 23
S247
M
F
V
F
S
G
Q
S
G
A
K
I
T
N
N
Site 24
T264
Q
F
E
F
K
D
K
T
W
T
R
I
P
T
E
Site 25
T266
E
F
K
D
K
T
W
T
R
I
P
T
E
H
L
Site 26
T270
K
T
W
T
R
I
P
T
E
H
L
L
R
G
S
Site 27
S277
T
E
H
L
L
R
G
S
P
P
P
P
Q
R
R
Site 28
Y285
P
P
P
P
Q
R
R
Y
G
H
T
M
V
A
F
Site 29
T288
P
Q
R
R
Y
G
H
T
M
V
A
F
D
R
H
Site 30
T306
F
G
G
A
A
D
N
T
L
P
N
E
L
H
C
Site 31
S328
W
E
V
V
Q
P
S
S
D
S
E
V
G
G
A
Site 32
S330
V
V
Q
P
S
S
D
S
E
V
G
G
A
E
V
Site 33
T349
C
A
S
E
E
V
P
T
L
T
Y
E
E
R
V
Site 34
T351
S
E
E
V
P
T
L
T
Y
E
E
R
V
G
F
Site 35
Y352
E
E
V
P
T
L
T
Y
E
E
R
V
G
F
K
Site 36
S361
E
R
V
G
F
K
K
S
R
D
V
F
G
L
D
Site 37
T371
V
F
G
L
D
F
G
T
T
S
A
K
Q
P
T
Site 38
S382
K
Q
P
T
Q
P
A
S
E
L
P
S
G
R
L
Site 39
S386
Q
P
A
S
E
L
P
S
G
R
L
F
H
A
A
Site 40
Y417
N
I
R
S
G
E
M
Y
R
F
Q
F
S
C
Y
Site 41
Y433
K
C
T
L
H
E
D
Y
G
R
L
W
E
S
R
Site 42
T464
Q
G
H
V
A
I
V
T
A
R
S
R
W
L
R
Site 43
T475
R
W
L
R
R
K
I
T
Q
A
R
E
R
L
A
Site 44
Y529
E
V
L
M
Q
F
L
Y
T
D
K
I
K
Y
P
Site 45
Y535
L
Y
T
D
K
I
K
Y
P
R
K
G
H
V
E
Site 46
Y569
L
E
Q
L
C
R
Q
Y
I
E
A
S
V
D
L
Site 47
S592
S
A
A
R
L
Q
L
S
Q
L
K
E
H
C
L
Site 48
T639
K
Q
Q
P
P
P
R
T
P
L
D
Q
P
V
D
Site 49
Y658
L
I
Q
D
M
K
A
Y
L
E
G
A
G
A
E
Site 50
S716
S
I
G
E
M
V
P
S
R
Q
A
F
E
S
M
Site 51
Y726
A
F
E
S
M
L
R
Y
I
Y
Y
G
E
V
N
Site 52
Y728
E
S
M
L
R
Y
I
Y
Y
G
E
V
N
M
P
Site 53
Y729
S
M
L
R
Y
I
Y
Y
G
E
V
N
M
P
P
Site 54
Y741
M
P
P
E
D
S
L
Y
L
F
A
A
P
Y
Y
Site 55
Y748
Y
L
F
A
A
P
Y
Y
Y
G
F
Y
N
N
R
Site 56
Y752
A
P
Y
Y
Y
G
F
Y
N
N
R
L
Q
A
Y
Site 57
T783
I
L
E
A
A
D
K
T
Q
A
L
D
M
K
R
Site 58
T808
T
K
V
S
K
L
P
T
L
R
S
L
S
Q
Q
Site 59
S811
S
K
L
P
T
L
R
S
L
S
Q
Q
L
L
L
Site 60
S829
D
S
L
A
S
H
I
S
D
K
Q
C
A
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation