PhosphoNET

           
Protein Info 
   
Short Name:  CPSF7
Full Name:  Cleavage and polyadenylation specificity factor subunit 7
Alias:  Cleavage and polyadenylation specificity factor 59 kDa subunit; FLJ12529; MRNA cleavage factor I 59 kDa; Pre-mRNA cleavage factor I, 59 kDa subunit
Type:  RNA binding protein, RNA processing
Mass (Da):  52050
Number AA:  471
UniProt ID:  Q8N684
International Prot ID:  IPI00550821
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634  GO:0043226  GO:0043227 Uniprot OncoNet
Molecular Function:  GO:0003723  GO:0000166  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0000398  GO:0000377  GO:0000398 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y11GVDLIDIYADEEFNQ
Site 2Y31NTDQIDLYDDVLTAT
Site 3T36DLYDDVLTATSQPSD
Site 4T38YDDVLTATSQPSDDR
Site 5S39DDVLTATSQPSDDRS
Site 6S42LTATSQPSDDRSSST
Site 7S46QPSDDRSSSTEPPPP
Site 8S47QPSDDRSSSTEPPPP
Site 9S48PSDDRSSSTEPPPPV
Site 10T49SDDRSSSTEPPPPVR
Site 11S60PPVRQEPSPKPNNKT
Site 12T67SPKPNNKTPAILYTY
Site 13Y72 NKTPAILYTYSGLRN
Site 14T73 KTPAILYTYSGLRNR
Site 15Y74TPAILYTYSGLRNRR
Site 16S75PAILYTYSGLRNRRA
Site 17Y85RNRRAAVYVGSFSWW
Site 18S124ENRANGQSKGYAEVV
Site 19T161KVDVRPATRQNLSQF
Site 20S166PATRQNLSQFEAQAR
Site 21S191GIPPRAHSRDSSDSA
Site 22S194PRAHSRDSSDSADGR
Site 23S195RAHSRDSSDSADGRA
Site 24S197HSRDSSDSADGRATP
Site 25T203DSADGRATPSENLVP
Site 26S205ADGRATPSENLVPSS
Site 27S211PSENLVPSSARVDKP
Site 28S212SENLVPSSARVDKPP
Site 29S220ARVDKPPSVLPYFNR
Site 30Y224KPPSVLPYFNRPPSA
Site 31S230PYFNRPPSALPLMGL
Site 32S249IPPPPPLSSSFGVPP
Site 33S250PPPPPLSSSFGVPPP
Site 34S251PPPPLSSSFGVPPPP
Site 35Y263PPPPGIHYQHLMPPP
Site 36T302FFPPPNATVGPPPDT
Site 37T309TVGPPPDTYMKASAP
Site 38Y310VGPPPDTYMKASAPY
Site 39S322APYNHHGSRDSGPPP
Site 40S325NHHGSRDSGPPPSTV
Site 41S330RDSGPPPSTVSEAEF
Site 42T331DSGPPPSTVSEAEFE
Site 43S333GPPPSTVSEAEFEDI
Site 44S348MKRNRAISSSAISKA
Site 45S349KRNRAISSSAISKAV
Site 46S350RNRAISSSAISKAVS
Site 47S357SAISKAVSGASAGDY
Site 48Y364SGASAGDYSDAIETL
Site 49S394ERCRVLISSLKDCLH
Site 50S407LHGIEAKSYSVGASG
Site 51Y408HGIEAKSYSVGASGS
Site 52S409GIEAKSYSVGASGSS
Site 53S413KSYSVGASGSSSRKR
Site 54S415YSVGASGSSSRKRHR
Site 55S416SVGASGSSSRKRHRS
Site 56S417VGASGSSSRKRHRSR
Site 57S423SSRKRHRSRERSPSR
Site 58S427RHRSRERSPSRSRES
Site 59S429RSRERSPSRSRESSR
Site 60S431RERSPSRSRESSRRH
Site 61S434SPSRSRESSRRHRDL
Site 62S435PSRSRESSRRHRDLL
Site 63Y451NEDRHDDYFQERNRE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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