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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA0859
Full Name:
Methyltransferase-like protein 13
Alias:
CGI-01; K0859; Methyltransferase like 13
Type:
Methyltransferase; EC 2.1.1.-
Mass (Da):
78768
Number AA:
699
UniProt ID:
Q8N6R0
International Prot ID:
IPI00514340
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0008168
PhosphoSite+
KinaseNET
Biological Process:
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
N
L
L
P
K
S
S
R
E
F
G
S
V
Site 2
S8
M
N
L
L
P
K
S
S
R
E
F
G
S
V
D
Site 3
S13
K
S
S
R
E
F
G
S
V
D
Y
W
E
K
F
Site 4
Y16
R
E
F
G
S
V
D
Y
W
E
K
F
F
Q
Q
Site 5
Y32
G
K
K
A
F
E
W
Y
G
T
Y
L
E
L
C
Site 6
Y35
A
F
E
W
Y
G
T
Y
L
E
L
C
G
V
L
Site 7
Y45
L
C
G
V
L
H
K
Y
I
K
P
R
E
K
V
Site 8
S63
G
C
G
N
S
E
L
S
E
Q
L
Y
D
V
G
Site 9
Y67
S
E
L
S
E
Q
L
Y
D
V
G
Y
R
D
I
Site 10
Y71
E
Q
L
Y
D
V
G
Y
R
D
I
V
N
I
D
Site 11
S99
A
T
R
R
P
Q
M
S
F
L
K
M
D
M
T
Site 12
T106
S
F
L
K
M
D
M
T
Q
M
E
F
P
D
A
Site 13
S114
Q
M
E
F
P
D
A
S
F
Q
V
V
L
D
K
Site 14
T129
G
T
L
D
A
V
L
T
D
E
E
E
K
T
L
Site 15
T135
L
T
D
E
E
E
K
T
L
Q
Q
V
D
R
M
Site 16
S175
K
K
A
V
G
H
F
S
R
E
G
W
M
V
R
Site 17
S189
R
V
H
Q
V
A
N
S
Q
D
Q
V
L
E
A
Site 18
S238
R
K
P
V
R
L
E
S
A
E
R
L
A
E
A
Site 19
Y252
A
V
Q
E
R
Q
Q
Y
A
W
L
C
S
Q
L
Site 20
S267
R
R
K
A
R
L
G
S
V
S
L
D
L
C
D
Site 21
S269
K
A
R
L
G
S
V
S
L
D
L
C
D
G
D
Site 22
T277
L
D
L
C
D
G
D
T
G
E
P
R
Y
T
L
Site 23
Y282
G
D
T
G
E
P
R
Y
T
L
H
V
V
D
S
Site 24
T283
D
T
G
E
P
R
Y
T
L
H
V
V
D
S
P
Site 25
S289
Y
T
L
H
V
V
D
S
P
T
V
K
P
S
R
Site 26
T291
L
H
V
V
D
S
P
T
V
K
P
S
R
D
N
Site 27
Y344
A
L
H
R
G
Q
Q
Y
E
S
M
D
H
I
Q
Site 28
T385
G
G
D
I
G
V
R
T
V
Q
H
Q
D
C
S
Site 29
S392
T
V
Q
H
Q
D
C
S
P
L
S
G
D
Y
V
Site 30
S395
H
Q
D
C
S
P
L
S
G
D
Y
V
I
E
D
Site 31
Y398
C
S
P
L
S
G
D
Y
V
I
E
D
V
Q
G
Site 32
Y410
V
Q
G
D
D
K
R
Y
F
R
R
L
I
F
L
Site 33
S418
F
R
R
L
I
F
L
S
N
R
N
V
V
Q
S
Site 34
S425
S
N
R
N
V
V
Q
S
E
A
R
L
L
K
D
Site 35
S434
A
R
L
L
K
D
V
S
H
K
A
Q
K
K
R
Site 36
S463
L
P
A
A
P
G
Q
S
I
D
K
S
Y
L
C
Site 37
Y468
G
Q
S
I
D
K
S
Y
L
C
C
E
H
H
K
Site 38
T582
D
V
D
S
K
D
P
T
L
G
M
S
C
P
P
Site 39
S586
K
D
P
T
L
G
M
S
C
P
P
P
A
F
V
Site 40
S596
P
P
A
F
V
E
Q
S
F
L
Q
K
V
K
S
Site 41
T662
H
P
E
Q
K
L
A
T
P
E
L
L
E
T
A
Site 42
T668
A
T
P
E
L
L
E
T
A
Q
A
L
E
R
T
Site 43
T675
T
A
Q
A
L
E
R
T
L
R
K
P
G
R
G
Site 44
T686
P
G
R
G
W
D
D
T
Y
V
L
S
D
M
L
Site 45
Y687
G
R
G
W
D
D
T
Y
V
L
S
D
M
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation