PhosphoNET

           
Protein Info 
   
Short Name:  ARFGAP1
Full Name:  ADP-ribosylation factor GTPase-activating protein 1
Alias:  ADP-ribosylation factor 1 GTPase activating protein; ADP-ribosylation factor 1 GTPase-activating protein; ADP-ribosylation factor GTPase activating protein 1; ARF1 GAP; ARF1-directed GTPase- activating protein; ARF1-directed GTPase-activating protein; ARF1GAP; ARFG1; ARG1; BA261N11.3; FLJ10767; GAP protein
Type:  GTPase-activating protein for G protein
Mass (Da):  44668
Number AA:  406
UniProt ID:  Q8N6T3
International Prot ID:  IPI00175169
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0000139     Uniprot OncoNet
Molecular Function:  GO:0008060  GO:0008270   PhosphoSite+ KinaseNET
Biological Process:  GO:0048205  GO:0015031  GO:0032312 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T63LSFVRSVTMDKWKDI
Site 2S89KFREFLESQEDYDPC
Site 3Y93FLESQEDYDPCWSLQ
Site 4S98EDYDPCWSLQEKYNS
Site 5Y103CWSLQEKYNSRAAAL
Site 6S105SLQEKYNSRAAALFR
Site 7S125LAEGREWSLESSPAQ
Site 8S128GREWSLESSPAQNWT
Site 9S129REWSLESSPAQNWTP
Site 10T135SSPAQNWTPPQPRTL
Site 11T141WTPPQPRTLPSMVHR
Site 12S144PQPRTLPSMVHRVSG
Site 13S150PSMVHRVSGQPQSVT
Site 14S155RVSGQPQSVTASSDK
Site 15T157SGQPQSVTASSDKAF
Site 16S159QPQSVTASSDKAFED
Site 17S160PQSVTASSDKAFEDW
Site 18S174WLNDDLGSYQGAQGN
Site 19Y175LNDDLGSYQGAQGNR
Site 20Y183QGAQGNRYVGFGNTP
Site 21T189RYVGFGNTPPPQKKE
Site 22S205DFLNNAMSSLYSGWS
Site 23S206FLNNAMSSLYSGWSS
Site 24Y208NNAMSSLYSGWSSFT
Site 25S209NAMSSLYSGWSSFTT
Site 26S212SSLYSGWSSFTTGAS
Site 27S213SLYSGWSSFTTGASR
Site 28T216SGWSSFTTGASRFAS
Site 29S219SSFTTGASRFASAAK
Site 30S223TGASRFASAAKEGAT
Site 31S234EGATKFGSQASQKAS
Site 32S237TKFGSQASQKASELG
Site 33S241SQASQKASELGHSLN
Site 34S246KASELGHSLNENVLK
Site 35S270KIFDDVSSGVSQLAS
Site 36S273DDVSSGVSQLASKVQ
Site 37S277SGVSQLASKVQGVGS
Site 38T291SKGWRDVTTFFSGKA
Site 39T292KGWRDVTTFFSGKAE
Site 40S304KAEGPLDSPSEGHSY
Site 41S306EGPLDSPSEGHSYQN
Site 42S310DSPSEGHSYQNSGLD
Site 43Y311SPSEGHSYQNSGLDH
Site 44S314EGHSYQNSGLDHFQN
Site 45T331IDQSFWETFGSAEPT
Site 46S334SFWETFGSAEPTKTR
Site 47T338TFGSAEPTKTRKSPS
Site 48T340GSAEPTKTRKSPSSD
Site 49S343EPTKTRKSPSSDSWT
Site 50S345TKTRKSPSSDSWTCA
Site 51S346KTRKSPSSDSWTCAD
Site 52S348RKSPSSDSWTCADTS
Site 53T350SPSSDSWTCADTSTE
Site 54S355SWTCADTSTERRSSD
Site 55T356WTCADTSTERRSSDS
Site 56S360DTSTERRSSDSWEVW
Site 57S361TSTERRSSDSWEVWG
Site 58S363TERRSSDSWEVWGSA
Site 59S369DSWEVWGSASTNRNS
Site 60S371WEVWGSASTNRNSNS
Site 61T372EVWGSASTNRNSNSD
Site 62S376SASTNRNSNSDGGEG
Site 63S378STNRNSNSDGGEGGE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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