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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EFCAB3
Full Name:
EF-hand calcium-binding domain-containing protein 3
Alias:
Type:
Mass (Da):
50147
Number AA:
438
UniProt ID:
Q8N7B9
International Prot ID:
IPI00167171
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
A
V
S
E
I
K
P
K
L
K
Site 2
T16
K
L
K
L
N
P
L
T
K
V
P
I
S
H
N
Site 3
S21
P
L
T
K
V
P
I
S
H
N
K
R
D
R
D
Site 4
S32
R
D
R
D
L
P
G
S
L
Q
C
Q
L
Q
H
Site 5
S45
Q
H
K
E
K
K
L
S
A
S
Q
M
A
A
F
Site 6
S47
K
E
K
K
L
S
A
S
Q
M
A
A
F
Q
D
Site 7
Y56
M
A
A
F
Q
D
A
Y
N
F
F
Y
K
D
K
Site 8
Y60
Q
D
A
Y
N
F
F
Y
K
D
K
T
G
C
I
Site 9
T84
A
K
L
G
M
N
L
T
K
H
D
V
Y
N
E
Site 10
Y89
N
L
T
K
H
D
V
Y
N
E
L
K
C
A
D
Site 11
S151
L
S
R
L
L
E
T
S
A
L
P
R
K
S
I
Site 12
Y164
S
I
I
E
I
V
S
Y
F
Q
R
K
F
Q
H
Site 13
T172
F
Q
R
K
F
Q
H
T
G
P
G
M
L
W
S
Site 14
Y181
P
G
M
L
W
S
P
Y
T
M
G
Y
G
K
R
Site 15
T196
T
L
K
P
D
I
C
T
P
P
S
S
S
M
A
Site 16
S231
E
E
L
K
R
C
N
S
G
S
D
S
P
Y
S
Site 17
S233
L
K
R
C
N
S
G
S
D
S
P
Y
S
K
I
Site 18
S235
R
C
N
S
G
S
D
S
P
Y
S
K
I
P
I
Site 19
Y237
N
S
G
S
D
S
P
Y
S
K
I
P
I
F
P
Site 20
S238
S
G
S
D
S
P
Y
S
K
I
P
I
F
P
L
Site 21
T288
F
H
K
R
D
W
K
T
Q
A
A
N
I
K
S
Site 22
S295
T
Q
A
A
N
I
K
S
M
D
P
A
S
G
Y
Site 23
S300
I
K
S
M
D
P
A
S
G
Y
S
N
N
I
F
Site 24
T320
L
K
K
K
Q
T
C
T
V
A
D
A
T
A
I
Site 25
T335
K
Q
H
V
K
R
A
T
D
T
Y
N
L
G
I
Site 26
Y338
V
K
R
A
T
D
T
Y
N
L
G
I
A
L
E
Site 27
S366
G
D
L
I
G
M
D
S
R
N
E
S
F
Y
D
Site 28
S370
G
M
D
S
R
N
E
S
F
Y
D
T
F
S
T
Site 29
Y372
D
S
R
N
E
S
F
Y
D
T
F
S
T
Y
T
Site 30
S390
N
V
C
Q
E
L
L
S
P
K
D
L
R
L
Y
Site 31
Y397
S
P
K
D
L
R
L
Y
D
A
Y
V
N
R
N
Site 32
Y400
D
L
R
L
Y
D
A
Y
V
N
R
N
S
S
H
Site 33
S405
D
A
Y
V
N
R
N
S
S
H
N
S
R
S
S
Site 34
S406
A
Y
V
N
R
N
S
S
H
N
S
R
S
S
S
Site 35
S409
N
R
N
S
S
H
N
S
R
S
S
S
S
S
D
Site 36
S411
N
S
S
H
N
S
R
S
S
S
S
S
D
T
S
Site 37
S412
S
S
H
N
S
R
S
S
S
S
S
D
T
S
E
Site 38
S413
S
H
N
S
R
S
S
S
S
S
D
T
S
E
C
Site 39
S414
H
N
S
R
S
S
S
S
S
D
T
S
E
C
Y
Site 40
S415
N
S
R
S
S
S
S
S
D
T
S
E
C
Y
T
Site 41
T417
R
S
S
S
S
S
D
T
S
E
C
Y
T
D
S
Site 42
S418
S
S
S
S
S
D
T
S
E
C
Y
T
D
S
G
Site 43
Y421
S
S
D
T
S
E
C
Y
T
D
S
G
R
K
R
Site 44
T422
S
D
T
S
E
C
Y
T
D
S
G
R
K
R
K
Site 45
S424
T
S
E
C
Y
T
D
S
G
R
K
R
K
R
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation