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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIML2
Full Name:
Probable E3 ubiquitin-protein ligase TRIML2
Alias:
SPRY domain-containing protein 6;Tripartite motif family-like protein 2
Type:
Mass (Da):
43983
Number AA:
387
UniProt ID:
Q8N7C3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T22
L
F
Q
E
I
L
N
T
S
R
E
K
L
E
A
Site 2
S32
E
K
L
E
A
A
K
S
I
L
T
D
E
Q
E
Site 3
S60
K
M
I
E
S
E
Y
S
M
R
L
R
L
L
N
Site 4
T89
S
D
L
N
L
R
E
T
L
L
N
Q
A
I
K
Site 5
S126
N
M
E
K
L
K
E
S
E
A
R
A
S
E
Q
Site 6
S131
K
E
S
E
A
R
A
S
E
Q
V
R
S
L
L
Site 7
S136
R
A
S
E
Q
V
R
S
L
L
K
L
I
V
E
Site 8
Y161
A
L
L
K
N
A
K
Y
S
L
E
R
S
K
S
Site 9
S162
L
L
K
N
A
K
Y
S
L
E
R
S
K
S
L
Site 10
S166
A
K
Y
S
L
E
R
S
K
S
L
L
L
E
H
Site 11
S168
Y
S
L
E
R
S
K
S
L
L
L
E
H
L
E
Site 12
S192
C
H
I
R
G
L
S
S
M
F
R
V
L
Q
R
Site 13
T202
R
V
L
Q
R
H
L
T
L
D
P
E
T
A
H
Site 14
S215
A
H
P
C
L
A
L
S
E
D
L
R
T
M
R
Site 15
T220
A
L
S
E
D
L
R
T
M
R
L
R
H
G
Q
Site 16
S251
L
A
A
E
S
F
T
S
G
R
H
Y
W
E
V
Site 17
Y255
S
F
T
S
G
R
H
Y
W
E
V
D
V
E
K
Site 18
S274
Q
V
G
I
Y
H
G
S
A
D
A
K
G
S
T
Site 19
S280
G
S
A
D
A
K
G
S
T
A
R
A
S
G
E
Site 20
T281
S
A
D
A
K
G
S
T
A
R
A
S
G
E
K
Site 21
S285
K
G
S
T
A
R
A
S
G
E
K
V
L
L
T
Site 22
Y334
E
H
G
Q
I
S
F
Y
N
V
T
E
M
S
L
Site 23
T367
L
C
I
P
N
G
D
T
S
P
D
S
L
T
I
Site 24
S368
C
I
P
N
G
D
T
S
P
D
S
L
T
I
L
Site 25
S371
N
G
D
T
S
P
D
S
L
T
I
L
Q
H
G
Site 26
T373
D
T
S
P
D
S
L
T
I
L
Q
H
G
P
S
Site 27
S380
T
I
L
Q
H
G
P
S
C
D
A
T
V
S
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation