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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF645
Full Name:
Zinc finger protein 645
Alias:
Type:
Mass (Da):
48785
Number AA:
425
UniProt ID:
Q8N7E2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y13
A
G
E
Q
E
C
E
Y
N
K
E
G
K
Y
Y
Site 2
Y19
E
Y
N
K
E
G
K
Y
Y
S
K
G
V
K
L
Site 3
Y20
Y
N
K
E
G
K
Y
Y
S
K
G
V
K
L
V
Site 4
S21
N
K
E
G
K
Y
Y
S
K
G
V
K
L
V
R
Site 5
Y36
K
K
K
K
I
P
G
Y
R
W
G
D
I
K
I
Site 6
Y85
C
Y
H
C
A
N
L
Y
D
K
V
G
Y
K
V
Site 7
Y98
K
V
C
P
R
C
R
Y
P
V
L
R
I
E
A
Site 8
Y124
V
Q
Q
C
K
R
T
Y
L
S
Q
K
S
L
Q
Site 9
S126
Q
C
K
R
T
Y
L
S
Q
K
S
L
Q
A
H
Site 10
S129
R
T
Y
L
S
Q
K
S
L
Q
A
H
I
K
R
Site 11
S147
R
A
R
K
Q
V
T
S
A
S
L
E
K
V
R
Site 12
S149
R
K
Q
V
T
S
A
S
L
E
K
V
R
P
H
Site 13
S165
A
P
P
Q
T
E
I
S
D
I
P
K
R
L
Q
Site 14
S178
L
Q
D
R
D
H
L
S
Y
I
P
P
E
Q
H
Site 15
Y179
Q
D
R
D
H
L
S
Y
I
P
P
E
Q
H
T
Site 16
T186
Y
I
P
P
E
Q
H
T
M
V
S
L
P
S
V
Site 17
S189
P
E
Q
H
T
M
V
S
L
P
S
V
Q
H
M
Site 18
S218
P
P
P
E
L
S
L
S
L
P
F
P
I
Q
W
Site 19
T227
P
F
P
I
Q
W
E
T
V
S
I
F
T
R
K
Site 20
T239
T
R
K
H
G
N
L
T
V
D
H
I
Q
N
N
Site 21
S249
H
I
Q
N
N
S
D
S
G
A
K
K
P
T
P
Site 22
T255
D
S
G
A
K
K
P
T
P
P
D
Y
Y
P
E
Site 23
Y259
K
K
P
T
P
P
D
Y
Y
P
E
C
Q
S
Q
Site 24
Y260
K
P
T
P
P
D
Y
Y
P
E
C
Q
S
Q
P
Site 25
S265
D
Y
Y
P
E
C
Q
S
Q
P
A
V
S
S
P
Site 26
S271
Q
S
Q
P
A
V
S
S
P
H
H
I
I
P
Q
Site 27
Y282
I
I
P
Q
K
Q
H
Y
A
P
P
P
S
P
S
Site 28
S287
Q
H
Y
A
P
P
P
S
P
S
S
P
V
N
H
Site 29
S289
Y
A
P
P
P
S
P
S
S
P
V
N
H
Q
M
Site 30
S290
A
P
P
P
S
P
S
S
P
V
N
H
Q
M
P
Site 31
Y298
P
V
N
H
Q
M
P
Y
P
P
Q
D
V
V
T
Site 32
T305
Y
P
P
Q
D
V
V
T
P
N
S
V
R
S
Q
Site 33
S308
Q
D
V
V
T
P
N
S
V
R
S
Q
V
P
A
Site 34
S311
V
T
P
N
S
V
R
S
Q
V
P
A
L
T
T
Site 35
T317
R
S
Q
V
P
A
L
T
T
T
Y
D
P
S
S
Site 36
T318
S
Q
V
P
A
L
T
T
T
Y
D
P
S
S
G
Site 37
T319
Q
V
P
A
L
T
T
T
Y
D
P
S
S
G
Y
Site 38
Y320
V
P
A
L
T
T
T
Y
D
P
S
S
G
Y
I
Site 39
S324
T
T
T
Y
D
P
S
S
G
Y
I
I
V
K
V
Site 40
S337
K
V
P
P
D
M
N
S
P
P
L
R
A
P
Q
Site 41
S345
P
P
L
R
A
P
Q
S
Q
N
G
N
P
S
A
Site 42
S351
Q
S
Q
N
G
N
P
S
A
S
E
F
A
S
H
Site 43
S353
Q
N
G
N
P
S
A
S
E
F
A
S
H
H
Y
Site 44
S357
P
S
A
S
E
F
A
S
H
H
Y
N
L
N
I
Site 45
T374
Q
F
T
E
N
Q
E
T
L
S
P
Q
F
T
Q
Site 46
S376
T
E
N
Q
E
T
L
S
P
Q
F
T
Q
T
D
Site 47
T380
E
T
L
S
P
Q
F
T
Q
T
D
A
M
D
H
Site 48
S397
W
P
A
W
K
R
L
S
P
C
P
P
T
R
S
Site 49
T402
R
L
S
P
C
P
P
T
R
S
P
P
P
S
T
Site 50
S404
S
P
C
P
P
T
R
S
P
P
P
S
T
L
H
Site 51
S408
P
T
R
S
P
P
P
S
T
L
H
G
R
S
H
Site 52
T409
T
R
S
P
P
P
S
T
L
H
G
R
S
H
H
Site 53
S417
L
H
G
R
S
H
H
S
H
Q
R
R
H
R
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation