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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
2600011E07Rik
Full Name:
Protein FAM123A
Alias:
F123A; family with sequence similarity 123A; FLJ25477; FLJ25477 protein
Type:
Mass (Da):
69531
Number AA:
671
UniProt ID:
Q8N7J2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
E
T
S
R
S
R
G
G
G
G
A
V
Site 2
S14
R
G
G
G
G
A
V
S
E
R
G
G
A
G
A
Site 3
S22
E
R
G
G
A
G
A
S
V
G
V
C
R
R
K
Site 4
T53
H
C
D
C
A
A
E
T
P
A
A
E
P
P
S
Site 5
S76
K
L
F
K
K
R
K
S
G
G
T
M
P
S
I
Site 6
T79
K
K
R
K
S
G
G
T
M
P
S
I
F
G
V
Site 7
S82
K
S
G
G
T
M
P
S
I
F
G
V
K
N
K
Site 8
S94
K
N
K
G
D
G
K
S
S
G
P
T
G
L
V
Site 9
S95
N
K
G
D
G
K
S
S
G
P
T
G
L
V
R
Site 10
T98
D
G
K
S
S
G
P
T
G
L
V
R
S
R
T
Site 11
T105
T
G
L
V
R
S
R
T
H
D
G
L
A
E
V
Site 12
S129
E
P
R
G
G
G
D
S
G
G
G
G
G
G
R
Site 13
S154
P
G
G
G
S
L
A
S
S
S
V
A
K
S
H
Site 14
S155
G
G
G
S
L
A
S
S
S
V
A
K
S
H
S
Site 15
S156
G
G
S
L
A
S
S
S
V
A
K
S
H
S
F
Site 16
S162
S
S
V
A
K
S
H
S
F
F
S
L
L
K
K
Site 17
S165
A
K
S
H
S
F
F
S
L
L
K
K
N
G
R
Site 18
S184
K
G
E
P
V
D
A
S
K
A
G
G
K
Q
K
Site 19
S199
R
G
L
R
G
L
F
S
G
M
R
W
H
R
K
Site 20
S229
G
G
L
I
L
P
G
S
L
T
A
S
L
E
C
Site 21
S233
L
P
G
S
L
T
A
S
L
E
C
V
K
E
E
Site 22
T241
L
E
C
V
K
E
E
T
P
R
A
A
R
E
P
Site 23
S280
A
D
R
A
P
A
R
S
C
R
E
A
E
G
L
Site 24
T293
G
L
A
H
P
G
D
T
G
A
R
G
E
D
A
Site 25
T315
P
G
P
G
E
V
R
T
A
E
D
A
S
R
T
Site 26
S335
K
T
V
P
L
V
D
S
E
G
G
S
G
R
A
Site 27
S339
L
V
D
S
E
G
G
S
G
R
A
P
A
A
P
Site 28
S350
P
A
A
P
D
P
A
S
V
D
P
P
S
D
P
Site 29
S355
P
A
S
V
D
P
P
S
D
P
S
A
D
R
I
Site 30
S358
V
D
P
P
S
D
P
S
A
D
R
I
C
L
M
Site 31
S374
S
D
V
T
S
L
K
S
F
D
S
L
T
G
C
Site 32
S377
T
S
L
K
S
F
D
S
L
T
G
C
G
D
I
Site 33
S395
Q
E
E
E
A
G
P
S
C
D
K
H
V
P
G
Site 34
S409
G
P
G
K
P
A
L
S
K
K
N
P
G
V
V
Site 35
Y418
K
N
P
G
V
V
A
Y
Q
G
G
G
E
E
M
Site 36
S427
G
G
G
E
E
M
A
S
P
D
E
V
D
D
T
Site 37
T434
S
P
D
E
V
D
D
T
Y
L
Q
E
F
W
D
Site 38
Y435
P
D
E
V
D
D
T
Y
L
Q
E
F
W
D
M
Site 39
S444
Q
E
F
W
D
M
L
S
Q
T
E
E
Q
G
P
Site 40
T472
E
T
K
V
V
P
E
T
P
K
D
T
R
C
V
Site 41
S487
E
A
A
K
D
A
S
S
V
K
R
R
R
L
N
Site 42
S520
Q
Q
E
G
V
P
N
S
D
E
G
Y
W
D
S
Site 43
Y524
V
P
N
S
D
E
G
Y
W
D
S
T
T
P
G
Site 44
S527
S
D
E
G
Y
W
D
S
T
T
P
G
P
E
E
Site 45
T528
D
E
G
Y
W
D
S
T
T
P
G
P
E
E
D
Site 46
T529
E
G
Y
W
D
S
T
T
P
G
P
E
E
D
S
Site 47
S536
T
P
G
P
E
E
D
S
S
S
S
G
K
K
A
Site 48
S537
P
G
P
E
E
D
S
S
S
S
G
K
K
A
G
Site 49
S538
G
P
E
E
D
S
S
S
S
G
K
K
A
G
I
Site 50
S549
K
A
G
I
P
R
D
S
Y
S
G
D
A
L
Y
Site 51
Y550
A
G
I
P
R
D
S
Y
S
G
D
A
L
Y
D
Site 52
S551
G
I
P
R
D
S
Y
S
G
D
A
L
Y
D
L
Site 53
Y556
S
Y
S
G
D
A
L
Y
D
L
Y
A
D
P
D
Site 54
Y559
G
D
A
L
Y
D
L
Y
A
D
P
D
G
S
P
Site 55
S565
L
Y
A
D
P
D
G
S
P
A
T
L
P
G
G
Site 56
T568
D
P
D
G
S
P
A
T
L
P
G
G
K
D
N
Site 57
T578
G
G
K
D
N
E
E
T
S
S
L
S
R
L
K
Site 58
S579
G
K
D
N
E
E
T
S
S
L
S
R
L
K
P
Site 59
S580
K
D
N
E
E
T
S
S
L
S
R
L
K
P
V
Site 60
S582
N
E
E
T
S
S
L
S
R
L
K
P
V
S
P
Site 61
T598
T
I
T
C
P
L
R
T
P
G
S
L
L
K
D
Site 62
S601
C
P
L
R
T
P
G
S
L
L
K
D
S
K
I
Site 63
S606
P
G
S
L
L
K
D
S
K
I
P
I
S
I
K
Site 64
S611
K
D
S
K
I
P
I
S
I
K
H
L
T
N
L
Site 65
T616
P
I
S
I
K
H
L
T
N
L
P
S
S
H
P
Site 66
S620
K
H
L
T
N
L
P
S
S
H
P
V
V
H
Q
Site 67
S621
H
L
T
N
L
P
S
S
H
P
V
V
H
Q
Q
Site 68
S630
P
V
V
H
Q
Q
P
S
R
S
E
M
P
R
T
Site 69
S632
V
H
Q
Q
P
S
R
S
E
M
P
R
T
K
I
Site 70
T637
S
R
S
E
M
P
R
T
K
I
P
V
S
K
V
Site 71
S642
P
R
T
K
I
P
V
S
K
V
L
V
R
R
V
Site 72
S650
K
V
L
V
R
R
V
S
N
R
G
L
A
G
T
Site 73
T657
S
N
R
G
L
A
G
T
T
I
R
A
T
A
C
Site 74
T662
A
G
T
T
I
R
A
T
A
C
H
D
S
A
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation