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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF433
Full Name:
Zinc finger protein 433
Alias:
FLJ40981; ZN433
Type:
Unknown function
Mass (Da):
77243
Number AA:
673
UniProt ID:
Q8N7K0
International Prot ID:
IPI00175202
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
A
F
E
D
V
A
V
T
F
T
Q
E
E
W
A
Site 2
S27
E
W
A
L
L
D
P
S
Q
K
N
L
C
R
D
Site 3
T39
C
R
D
V
M
Q
E
T
F
R
N
L
A
S
I
Site 4
Y56
K
W
K
P
Q
N
I
Y
V
E
Y
E
N
L
R
Site 5
Y59
P
Q
N
I
Y
V
E
Y
E
N
L
R
R
N
L
Site 6
S76
V
G
E
R
L
F
E
S
K
E
G
H
Q
H
G
Site 7
T87
H
Q
H
G
E
I
L
T
Q
V
P
D
D
M
L
Site 8
T97
P
D
D
M
L
K
K
T
T
T
G
V
K
S
C
Site 9
T99
D
M
L
K
K
T
T
T
G
V
K
S
C
E
S
Site 10
S103
K
T
T
T
G
V
K
S
C
E
S
S
V
Y
G
Site 11
S106
T
G
V
K
S
C
E
S
S
V
Y
G
E
V
G
Site 12
S107
G
V
K
S
C
E
S
S
V
Y
G
E
V
G
S
Site 13
Y109
K
S
C
E
S
S
V
Y
G
E
V
G
S
A
H
Site 14
S114
S
V
Y
G
E
V
G
S
A
H
S
S
L
N
R
Site 15
S118
E
V
G
S
A
H
S
S
L
N
R
H
I
R
D
Site 16
T127
N
R
H
I
R
D
D
T
G
H
K
A
Y
E
Y
Site 17
Y132
D
D
T
G
H
K
A
Y
E
Y
Q
E
Y
G
Q
Site 18
Y134
T
G
H
K
A
Y
E
Y
Q
E
Y
G
Q
K
P
Site 19
Y137
K
A
Y
E
Y
Q
E
Y
G
Q
K
P
Y
K
C
Site 20
Y142
Q
E
Y
G
Q
K
P
Y
K
C
K
Y
C
K
K
Site 21
T159
N
C
L
S
S
V
Q
T
H
E
R
A
H
S
G
Site 22
S165
Q
T
H
E
R
A
H
S
G
R
K
L
Y
V
C
Site 23
Y170
A
H
S
G
R
K
L
Y
V
C
E
E
C
G
K
Site 24
S183
G
K
T
F
I
S
H
S
N
L
Q
R
H
R
I
Site 25
Y198
M
H
R
G
D
G
P
Y
K
C
K
F
C
G
K
Site 26
T219
L
Y
L
I
H
K
R
T
H
T
G
E
K
P
Y
Site 27
T221
L
I
H
K
R
T
H
T
G
E
K
P
Y
Q
C
Site 28
Y226
T
H
T
G
E
K
P
Y
Q
C
K
Q
C
G
K
Site 29
S236
K
Q
C
G
K
A
F
S
H
S
S
S
L
R
I
Site 30
S238
C
G
K
A
F
S
H
S
S
S
L
R
I
H
E
Site 31
S239
G
K
A
F
S
H
S
S
S
L
R
I
H
E
R
Site 32
S240
K
A
F
S
H
S
S
S
L
R
I
H
E
R
T
Site 33
T247
S
L
R
I
H
E
R
T
H
T
G
E
K
P
Y
Site 34
T249
R
I
H
E
R
T
H
T
G
E
K
P
Y
K
C
Site 35
Y254
T
H
T
G
E
K
P
Y
K
C
N
E
C
G
K
Site 36
T275
C
L
H
A
H
K
R
T
H
T
G
E
K
P
Y
Site 37
T277
H
A
H
K
R
T
H
T
G
E
K
P
Y
E
C
Site 38
Y282
T
H
T
G
E
K
P
Y
E
C
K
Q
C
G
K
Site 39
S292
K
Q
C
G
K
A
F
S
S
S
H
S
F
Q
I
Site 40
S293
Q
C
G
K
A
F
S
S
S
H
S
F
Q
I
H
Site 41
S294
C
G
K
A
F
S
S
S
H
S
F
Q
I
H
E
Site 42
S296
K
A
F
S
S
S
H
S
F
Q
I
H
E
R
T
Site 43
T303
S
F
Q
I
H
E
R
T
H
T
G
E
K
P
Y
Site 44
T305
Q
I
H
E
R
T
H
T
G
E
K
P
Y
E
C
Site 45
Y310
T
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 46
S323
G
K
A
F
K
C
P
S
S
V
R
R
H
E
R
Site 47
S324
K
A
F
K
C
P
S
S
V
R
R
H
E
R
T
Site 48
T331
S
V
R
R
H
E
R
T
H
S
R
K
K
P
Y
Site 49
S333
R
R
H
E
R
T
H
S
R
K
K
P
Y
E
C
Site 50
Y338
T
H
S
R
K
K
P
Y
E
C
K
H
C
G
K
Site 51
S348
K
H
C
G
K
V
L
S
Y
L
T
S
F
Q
N
Site 52
Y349
H
C
G
K
V
L
S
Y
L
T
S
F
Q
N
H
Site 53
Y376
K
I
C
G
K
A
F
Y
S
P
S
S
L
Q
T
Site 54
S377
I
C
G
K
A
F
Y
S
P
S
S
L
Q
T
H
Site 55
S379
G
K
A
F
Y
S
P
S
S
L
Q
T
H
E
K
Site 56
S380
K
A
F
Y
S
P
S
S
L
Q
T
H
E
K
T
Site 57
T383
Y
S
P
S
S
L
Q
T
H
E
K
T
H
T
G
Site 58
T387
S
L
Q
T
H
E
K
T
H
T
G
E
K
P
Y
Site 59
T389
Q
T
H
E
K
T
H
T
G
E
K
P
Y
K
C
Site 60
Y394
T
H
T
G
E
K
P
Y
K
C
N
Q
C
G
K
Site 61
S405
Q
C
G
K
A
F
N
S
S
S
S
F
R
Y
H
Site 62
S406
C
G
K
A
F
N
S
S
S
S
F
R
Y
H
E
Site 63
S407
G
K
A
F
N
S
S
S
S
F
R
Y
H
E
R
Site 64
S408
K
A
F
N
S
S
S
S
F
R
Y
H
E
R
T
Site 65
Y411
N
S
S
S
S
F
R
Y
H
E
R
T
H
T
G
Site 66
T415
S
F
R
Y
H
E
R
T
H
T
G
E
K
P
Y
Site 67
T417
R
Y
H
E
R
T
H
T
G
E
K
P
Y
E
C
Site 68
S435
G
K
A
F
R
S
A
S
L
L
Q
T
H
G
R
Site 69
T439
R
S
A
S
L
L
Q
T
H
G
R
T
H
T
G
Site 70
T443
L
L
Q
T
H
G
R
T
H
T
G
E
K
P
Y
Site 71
T445
Q
T
H
G
R
T
H
T
G
E
K
P
Y
A
C
Site 72
Y450
T
H
T
G
E
K
P
Y
A
C
K
E
C
G
K
Site 73
S463
G
K
P
F
S
N
F
S
F
F
Q
I
H
E
R
Site 74
Y478
M
H
R
E
E
K
P
Y
E
C
K
G
Y
G
K
Site 75
Y483
K
P
Y
E
C
K
G
Y
G
K
T
F
S
L
P
Site 76
T486
E
C
K
G
Y
G
K
T
F
S
L
P
S
L
F
Site 77
S488
K
G
Y
G
K
T
F
S
L
P
S
L
F
H
R
Site 78
S491
G
K
T
F
S
L
P
S
L
F
H
R
H
E
R
Site 79
T501
H
R
H
E
R
T
H
T
G
G
K
T
Y
E
C
Site 80
T505
R
T
H
T
G
G
K
T
Y
E
C
K
Q
C
G
Site 81
Y506
T
H
T
G
G
K
T
Y
E
C
K
Q
C
G
R
Site 82
S514
E
C
K
Q
C
G
R
S
F
N
C
S
S
S
F
Site 83
S518
C
G
R
S
F
N
C
S
S
S
F
R
Y
H
G
Site 84
S519
G
R
S
F
N
C
S
S
S
F
R
Y
H
G
R
Site 85
S520
R
S
F
N
C
S
S
S
F
R
Y
H
G
R
T
Site 86
Y523
N
C
S
S
S
F
R
Y
H
G
R
T
H
T
G
Site 87
T527
S
F
R
Y
H
G
R
T
H
T
G
E
K
P
Y
Site 88
T529
R
Y
H
G
R
T
H
T
G
E
K
P
Y
E
C
Site 89
S545
Q
C
G
K
A
F
R
S
A
S
Q
L
Q
I
H
Site 90
S547
G
K
A
F
R
S
A
S
Q
L
Q
I
H
G
R
Site 91
T555
Q
L
Q
I
H
G
R
T
H
T
G
E
K
P
Y
Site 92
T557
Q
I
H
G
R
T
H
T
G
E
K
P
Y
E
C
Site 93
S575
G
K
A
F
G
S
A
S
H
L
Q
M
H
G
R
Site 94
T583
H
L
Q
M
H
G
R
T
H
T
G
E
K
P
Y
Site 95
T585
Q
M
H
G
R
T
H
T
G
E
K
P
Y
E
C
Site 96
S598
E
C
K
Q
C
G
K
S
F
G
C
A
S
R
L
Site 97
S603
G
K
S
F
G
C
A
S
R
L
Q
M
H
G
R
Site 98
T611
R
L
Q
M
H
G
R
T
H
T
G
E
K
P
Y
Site 99
T613
Q
M
H
G
R
T
H
T
G
E
K
P
Y
K
C
Site 100
S631
G
K
A
F
G
C
P
S
N
L
R
R
H
G
R
Site 101
T639
N
L
R
R
H
G
R
T
H
T
G
E
K
P
Y
Site 102
T641
R
R
H
G
R
T
H
T
G
E
K
P
Y
K
C
Site 103
S659
G
K
V
F
R
C
S
S
Q
L
Q
V
H
G
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation