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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANKRD44
Full Name:
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
Alias:
Ankyrin repeat domain-containing protein 44
Type:
Mass (Da):
107603
Number AA:
993
UniProt ID:
Q8N8A2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
P
L
V
Q
A
I
F
S
G
D
P
E
E
I
R
Site 2
T31
I
R
M
L
I
H
K
T
E
D
V
N
T
L
D
Site 3
T36
H
K
T
E
D
V
N
T
L
D
S
E
K
R
T
Site 4
S39
E
D
V
N
T
L
D
S
E
K
R
T
P
L
H
Site 5
T43
T
L
D
S
E
K
R
T
P
L
H
V
A
A
F
Site 6
T76
A
K
D
N
M
W
L
T
P
L
H
R
A
V
A
Site 7
S86
H
R
A
V
A
S
R
S
E
E
A
V
Q
V
L
Site 8
T109
A
R
D
K
N
W
Q
T
P
L
H
V
A
A
A
Site 9
S136
L
L
S
S
V
N
V
S
D
R
G
G
R
T
A
Site 10
T208
C
K
D
K
K
G
Y
T
P
L
H
A
A
A
S
Site 11
Y238
E
I
D
E
I
N
V
Y
G
N
T
A
L
H
I
Site 12
Y261
V
V
N
E
L
I
D
Y
G
A
N
V
N
Q
P
Site 13
T274
Q
P
N
N
N
G
F
T
P
L
H
F
A
A
A
Site 14
S303
G
A
D
V
N
I
Q
S
K
D
G
K
S
P
L
Site 15
S308
I
Q
S
K
D
G
K
S
P
L
H
M
T
A
V
Site 16
T320
T
A
V
H
G
R
F
T
R
S
Q
T
L
I
Q
Site 17
S322
V
H
G
R
F
T
R
S
Q
T
L
I
Q
N
G
Site 18
T324
G
R
F
T
R
S
Q
T
L
I
Q
N
G
G
E
Site 19
T341
C
V
D
K
D
G
N
T
P
L
H
V
A
A
R
Site 20
Y349
P
L
H
V
A
A
R
Y
G
H
E
L
L
I
N
Site 21
S394
C
C
R
K
L
L
S
S
G
F
E
I
D
T
P
Site 22
T400
S
S
G
F
E
I
D
T
P
D
K
F
G
R
T
Site 23
S427
C
I
K
L
L
Q
S
S
G
A
D
F
H
K
K
Site 24
T440
K
K
D
K
C
G
R
T
P
L
H
Y
A
A
A
Site 25
Y477
W
G
R
T
A
L
H
Y
A
A
A
S
D
M
D
Site 26
T488
S
D
M
D
R
N
K
T
I
L
G
N
A
H
D
Site 27
S497
L
G
N
A
H
D
N
S
E
E
L
E
R
A
R
Site 28
S526
L
Q
N
D
A
N
P
S
I
R
D
K
E
G
Y
Site 29
Y533
S
I
R
D
K
E
G
Y
N
S
I
H
Y
A
A
Site 30
Y538
E
G
Y
N
S
I
H
Y
A
A
A
Y
G
H
R
Site 31
Y542
S
I
H
Y
A
A
A
Y
G
H
R
Q
C
L
E
Site 32
T555
L
E
L
L
L
E
R
T
N
S
G
F
E
E
S
Site 33
S557
L
L
L
E
R
T
N
S
G
F
E
E
S
D
S
Site 34
S562
T
N
S
G
F
E
E
S
D
S
G
A
T
K
S
Site 35
S564
S
G
F
E
E
S
D
S
G
A
T
K
S
P
L
Site 36
S569
S
D
S
G
A
T
K
S
P
L
H
L
A
A
Y
Site 37
Y576
S
P
L
H
L
A
A
Y
N
G
H
H
Q
A
L
Site 38
T602
I
R
D
E
K
G
R
T
A
L
D
L
A
A
F
Site 39
T633
I
F
V
K
D
N
V
T
K
R
T
P
L
H
A
Site 40
T636
K
D
N
V
T
K
R
T
P
L
H
A
S
V
I
Site 41
S641
K
R
T
P
L
H
A
S
V
I
N
G
H
T
L
Site 42
T698
E
K
E
A
N
V
D
T
V
D
I
L
G
C
T
Site 43
S728
M
L
L
E
Q
E
V
S
I
L
C
K
D
S
R
Site 44
S734
V
S
I
L
C
K
D
S
R
G
R
T
P
L
H
Site 45
T738
C
K
D
S
R
G
R
T
P
L
H
Y
A
A
A
Site 46
Y742
R
G
R
T
P
L
H
Y
A
A
A
R
G
H
A
Site 47
S761
E
L
L
Q
M
A
L
S
E
E
D
C
C
F
K
Site 48
S833
A
I
D
S
S
I
V
S
C
R
D
D
K
G
R
Site 49
T841
C
R
D
D
K
G
R
T
P
L
H
A
A
A
F
Site 50
T900
N
S
A
Q
A
D
L
T
V
K
D
K
D
L
N
Site 51
T908
V
K
D
K
D
L
N
T
P
L
H
L
A
C
S
Site 52
S915
T
P
L
H
L
A
C
S
K
G
H
E
K
C
A
Site 53
T944
E
K
N
N
A
L
Q
T
P
L
H
V
A
A
R
Site 54
S978
V
D
E
N
A
S
R
S
N
G
P
R
S
T
P
Site 55
S983
S
R
S
N
G
P
R
S
T
P
G
T
A
V
Q
Site 56
T984
R
S
N
G
P
R
S
T
P
G
T
A
V
Q
K
Site 57
T987
G
P
R
S
T
P
G
T
A
V
Q
K
E
E
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation