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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TCEANC
Full Name:
Transcription elongation factor A N-terminal and central domain-containing protein
Alias:
TFIIS central domain-containing protein 1
Type:
Mass (Da):
40245
Number AA:
351
UniProt ID:
Q8N8B7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
S
L
I
E
Q
L
M
S
K
R
N
F
E
D
L
Site 2
T31
E
D
L
G
N
H
L
T
E
L
E
T
I
Y
V
Site 3
Y37
L
T
E
L
E
T
I
Y
V
T
K
E
H
L
Q
Site 4
S61
R
V
L
K
N
C
P
S
V
A
L
K
K
K
A
Site 5
S73
K
K
A
K
C
L
L
S
K
W
K
A
V
Y
K
Site 6
S84
A
V
Y
K
Q
T
H
S
K
A
R
N
S
P
K
Site 7
S89
T
H
S
K
A
R
N
S
P
K
L
F
P
V
R
Site 8
S106
K
E
E
N
S
G
P
S
H
D
P
S
Q
N
E
Site 9
S110
S
G
P
S
H
D
P
S
Q
N
E
T
L
G
I
Site 10
T114
H
D
P
S
Q
N
E
T
L
G
I
C
S
S
N
Site 11
S119
N
E
T
L
G
I
C
S
S
N
S
L
S
S
Q
Site 12
S120
E
T
L
G
I
C
S
S
N
S
L
S
S
Q
D
Site 13
S122
L
G
I
C
S
S
N
S
L
S
S
Q
D
V
A
Site 14
S124
I
C
S
S
N
S
L
S
S
Q
D
V
A
K
L
Site 15
S132
S
Q
D
V
A
K
L
S
E
M
I
V
P
E
N
Site 16
S158
F
G
D
G
D
P
E
S
T
G
K
R
S
S
E
Site 17
T159
G
D
G
D
P
E
S
T
G
K
R
S
S
E
L
Site 18
S164
E
S
T
G
K
R
S
S
E
L
L
D
P
T
T
Site 19
T170
S
S
E
L
L
D
P
T
T
P
M
R
T
K
C
Site 20
T171
S
E
L
L
D
P
T
T
P
M
R
T
K
C
I
Site 21
T186
E
L
L
Y
A
A
L
T
S
S
S
T
D
Q
P
Site 22
S188
L
Y
A
A
L
T
S
S
S
T
D
Q
P
K
A
Site 23
T211
E
I
E
E
H
V
F
T
L
Y
S
K
N
I
K
Site 24
Y213
E
E
H
V
F
T
L
Y
S
K
N
I
K
K
Y
Site 25
Y220
Y
S
K
N
I
K
K
Y
K
T
C
I
R
S
K
Site 26
T222
K
N
I
K
K
Y
K
T
C
I
R
S
K
V
A
Site 27
S237
N
L
K
N
P
R
N
S
H
L
Q
Q
N
L
L
Site 28
S245
H
L
Q
Q
N
L
L
S
G
T
T
S
P
R
E
Site 29
S249
N
L
L
S
G
T
T
S
P
R
E
F
A
E
M
Site 30
T257
P
R
E
F
A
E
M
T
V
M
E
M
A
N
K
Site 31
S272
E
L
K
Q
L
R
A
S
Y
T
E
S
C
I
Q
Site 32
Y273
L
K
Q
L
R
A
S
Y
T
E
S
C
I
Q
E
Site 33
T274
K
Q
L
R
A
S
Y
T
E
S
C
I
Q
E
H
Site 34
S276
L
R
A
S
Y
T
E
S
C
I
Q
E
H
Y
L
Site 35
Y282
E
S
C
I
Q
E
H
Y
L
P
Q
V
I
D
G
Site 36
T290
L
P
Q
V
I
D
G
T
Q
T
N
K
I
K
C
Site 37
Y303
K
C
R
R
C
E
K
Y
N
C
K
V
T
V
I
Site 38
T308
E
K
Y
N
C
K
V
T
V
I
D
R
G
T
L
Site 39
S319
R
G
T
L
F
L
P
S
W
V
R
N
S
N
P
Site 40
S324
L
P
S
W
V
R
N
S
N
P
D
E
Q
M
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation