KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
GBP7
Full Name:
Guanylate-binding protein 7
Alias:
GTP-binding protein 7;Guanine nucleotide-binding protein 7;Guanylate-binding protein 4-like
Type:
Mass (Da):
72525
Number AA:
638
UniProt ID:
Q8N8V2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S52
G
L
Y
R
T
G
K
S
Y
L
M
N
K
L
A
Site 2
Y53
L
Y
R
T
G
K
S
Y
L
M
N
K
L
A
G
Site 3
T70
K
G
F
P
L
G
C
T
V
K
S
E
T
K
G
Site 4
S107
G
L
G
D
M
E
K
S
D
P
K
S
D
S
W
Site 5
S111
M
E
K
S
D
P
K
S
D
S
W
I
F
A
L
Site 6
S113
K
S
D
P
K
S
D
S
W
I
F
A
L
A
V
Site 7
Y128
L
L
S
S
S
F
V
Y
N
S
M
G
T
I
N
Site 8
S130
S
S
S
F
V
Y
N
S
M
G
T
I
N
H
Q
Site 9
Y144
Q
A
L
E
Q
L
H
Y
V
T
E
L
T
E
L
Site 10
S156
T
E
L
I
R
A
K
S
C
P
R
P
D
E
V
Site 11
S166
R
P
D
E
V
E
D
S
S
E
F
V
S
F
F
Site 12
S167
P
D
E
V
E
D
S
S
E
F
V
S
F
F
P
Site 13
S171
E
D
S
S
E
F
V
S
F
F
P
D
F
I
W
Site 14
T195
K
L
D
G
H
P
I
T
E
D
E
Y
L
E
N
Site 15
Y199
H
P
I
T
E
D
E
Y
L
E
N
A
L
K
L
Site 16
S259
V
R
E
D
Q
L
D
S
N
F
Q
M
Q
S
E
Site 17
T274
N
F
C
S
Y
I
F
T
H
A
K
T
K
T
L
Site 18
T280
F
T
H
A
K
T
K
T
L
R
E
G
I
L
V
Site 19
T308
D
A
I
N
S
G
A
T
P
C
L
E
N
A
M
Site 20
T346
A
Q
Q
V
R
F
P
T
D
T
L
Q
E
L
L
Site 21
T348
Q
V
R
F
P
T
D
T
L
Q
E
L
L
D
V
Site 22
S371
I
A
V
F
M
E
Y
S
F
K
D
K
S
Q
E
Site 23
S376
E
Y
S
F
K
D
K
S
Q
E
F
Q
K
K
L
Site 24
S414
Q
A
E
L
K
R
L
S
E
L
L
T
E
S
I
Site 25
T418
K
R
L
S
E
L
L
T
E
S
I
S
R
G
T
Site 26
T425
T
E
S
I
S
R
G
T
F
F
V
P
G
G
H
Site 27
Y435
V
P
G
G
H
N
I
Y
L
E
A
K
K
K
I
Site 28
Y446
K
K
K
I
E
Q
D
Y
T
L
V
P
R
K
G
Site 29
T447
K
K
I
E
Q
D
Y
T
L
V
P
R
K
G
V
Site 30
S462
K
A
D
E
V
L
Q
S
F
L
Q
S
Q
V
V
Site 31
S477
I
E
E
S
I
L
Q
S
D
K
A
L
T
A
G
Site 32
S522
M
M
E
A
Q
E
R
S
F
Q
E
N
I
A
Q
Site 33
Y541
M
E
R
E
R
E
N
Y
M
R
E
L
R
K
M
Site 34
S550
R
E
L
R
K
M
L
S
H
K
M
K
V
L
E
Site 35
S570
G
F
K
E
I
F
E
S
L
N
E
E
I
N
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation