PhosphoNET

           
Protein Info 
   
Short Name:  PNPLA1
Full Name:  Patatin-like phospholipase domain-containing protein 1
Alias: 
Type: 
Mass (Da):  57875
Number AA:  532
UniProt ID:  Q8N8W4
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T12VFKGDPDTPHSISFS
Site 2S15GDPDTPHSISFSGSG
Site 3S17PDTPHSISFSGSGFL
Site 4S21HSISFSGSGFLSFYQ
Site 5S91KSFLGPLSPSCKMVQ
Site 6S93FLGPLSPSCKMVQMM
Site 7Y105QMMRQFLYRVLPEDS
Site 8Y113RVLPEDSYKVTTGKL
Site 9T116PEDSYKVTTGKLHVS
Site 10S123TTGKLHVSLTRLTDG
Site 11T125GKLHVSLTRLTDGEN
Site 12Y165CGLIPPTYRGVRYID
Site 13Y170PTYRGVRYIDGGFTG
Site 14T192TDAITISTFSGQQDI
Site 15T229LENIARMTHALFPPD
Site 16Y243DLVILHDYYYRGYED
Site 17Y244LVILHDYYYRGYEDA
Site 18Y245VILHDYYYRGYEDAV
Site 19Y248HDYYYRGYEDAVLYL
Site 20Y262LRRLNAVYLNSSSKR
Site 21S267AVYLNSSSKRVIFPR
Site 22S293GNECPERSQPSLRAR
Site 23S296CPERSQPSLRARQAS
Site 24S303SLRARQASLEGATQP
Site 25S323PKGDGRGSHGPPVSQ
Site 26S329GSHGPPVSQPVQTLE
Site 27S348SPVSAPVSPLEQPPA
Site 28S360PPAQPLASSTPLSLS
Site 29S361PAQPLASSTPLSLSG
Site 30S382PAVHKPPSSTPGSSL
Site 31S383AVHKPPSSTPGSSLP
Site 32T384VHKPPSSTPGSSLPT
Site 33S387PPSSTPGSSLPTPPP
Site 34S388PSSTPGSSLPTPPPG
Site 35T391TPGSSLPTPPPGLSP
Site 36S397PTPPPGLSPLSPQQQ
Site 37S400PPGLSPLSPQQQVQP
Site 38S408PQQQVQPSGSPARSL
Site 39S410QQVQPSGSPARSLHS
Site 40S414PSGSPARSLHSQAPT
Site 41S417SPARSLHSQAPTSHR
Site 42T421SLHSQAPTSHRPSLG
Site 43S422LHSQAPTSHRPSLGP
Site 44S426APTSHRPSLGPSTVG
Site 45S430HRPSLGPSTVGAPQT
Site 46T431RPSLGPSTVGAPQTL
Site 47T437STVGAPQTLPRSSLS
Site 48S441APQTLPRSSLSAFPA
Site 49S442PQTLPRSSLSAFPAQ
Site 50S444TLPRSSLSAFPAQPP
Site 51Y488KETVSKPYVTESPAE
Site 52S492SKPYVTESPAEDSNW
Site 53S512KKNKQKTSGTRKGFP
Site 54S522RKGFPRHSGSKKPSS
Site 55S524GFPRHSGSKKPSSKV
Site 56S528HSGSKKPSSKVQ___
Site 57S529SGSKKPSSKVQ____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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