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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF441
Full Name:
Zinc finger protein 441
Alias:
Type:
Mass (Da):
72193
Number AA:
626
UniProt ID:
Q8N8Z8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
A
C
E
I
K
D
N
S
Q
C
G
G
P
F
T
Site 2
T19
S
Q
C
G
G
P
F
T
Q
T
Q
D
S
I
V
Site 3
S24
P
F
T
Q
T
Q
D
S
I
V
N
E
K
I
P
Site 4
S39
G
V
D
P
W
E
S
S
E
C
T
D
V
L
M
Site 5
T42
P
W
E
S
S
E
C
T
D
V
L
M
G
R
S
Site 6
Y54
G
R
S
S
L
N
C
Y
I
R
V
D
S
E
H
Site 7
Y64
V
D
S
E
H
K
P
Y
E
Y
Q
E
Y
G
E
Site 8
Y66
S
E
H
K
P
Y
E
Y
Q
E
Y
G
E
K
P
Site 9
Y69
K
P
Y
E
Y
Q
E
Y
G
E
K
P
Y
T
H
Site 10
T75
E
Y
G
E
K
P
Y
T
H
T
Q
C
G
T
A
Site 11
T77
G
E
K
P
Y
T
H
T
Q
C
G
T
A
F
S
Site 12
Y102
P
Q
H
G
K
K
L
Y
D
C
K
E
C
A
S
Site 13
S109
Y
D
C
K
E
C
A
S
F
S
S
L
E
N
L
Site 14
S112
K
E
C
A
S
F
S
S
L
E
N
L
Q
R
H
Site 15
T150
L
F
H
M
L
R
R
T
H
T
E
E
K
P
Y
Site 16
T152
H
M
L
R
R
T
H
T
E
E
K
P
Y
E
Y
Site 17
Y157
T
H
T
E
E
K
P
Y
E
Y
E
Q
C
S
T
Site 18
Y159
T
E
E
K
P
Y
E
Y
E
Q
C
S
T
A
F
Site 19
T164
Y
E
Y
E
Q
C
S
T
A
F
P
A
Y
S
S
Site 20
T172
A
F
P
A
Y
S
S
T
L
R
H
E
R
T
H
Site 21
T178
S
T
L
R
H
E
R
T
H
S
G
E
K
P
Y
Site 22
S180
L
R
H
E
R
T
H
S
G
E
K
P
Y
Q
C
Site 23
Y185
T
H
S
G
E
K
P
Y
Q
C
K
Q
C
G
K
Site 24
Y199
K
A
F
S
C
S
C
Y
T
Q
L
Y
E
R
T
Site 25
Y203
C
S
C
Y
T
Q
L
Y
E
R
T
H
T
G
E
Site 26
T208
Q
L
Y
E
R
T
H
T
G
E
Q
S
Y
E
C
Site 27
Y213
T
H
T
G
E
Q
S
Y
E
C
K
Q
C
G
K
Site 28
Y223
K
Q
C
G
K
A
F
Y
H
L
G
S
F
Q
R
Site 29
S252
I
C
G
K
G
F
L
S
P
S
S
V
R
R
H
Site 30
S254
G
K
G
F
L
S
P
S
S
V
R
R
H
K
R
Site 31
S255
K
G
F
L
S
P
S
S
V
R
R
H
K
R
T
Site 32
T262
S
V
R
R
H
K
R
T
H
T
G
E
K
P
Y
Site 33
T264
R
R
H
K
R
T
H
T
G
E
K
P
Y
E
C
Site 34
Y269
T
H
T
G
E
K
P
Y
E
C
K
Y
C
G
K
Site 35
Y273
E
K
P
Y
E
C
K
Y
C
G
K
A
F
S
D
Site 36
T290
G
F
R
R
H
M
I
T
H
T
G
D
G
P
H
Site 37
S308
V
C
G
K
A
F
D
S
P
S
L
C
R
R
H
Site 38
S310
G
K
A
F
D
S
P
S
L
C
R
R
H
E
T
Site 39
T317
S
L
C
R
R
H
E
T
A
H
T
G
E
K
P
Site 40
T320
R
R
H
E
T
A
H
T
G
E
K
P
Y
K
C
Site 41
Y337
G
K
A
F
S
D
F
Y
Y
F
R
N
H
E
T
Site 42
Y338
K
A
F
S
D
F
Y
Y
F
R
N
H
E
T
T
Site 43
T345
Y
F
R
N
H
E
T
T
H
T
G
E
K
P
Y
Site 44
T347
R
N
H
E
T
T
H
T
G
E
K
P
Y
K
C
Site 45
T375
Q
I
H
E
R
I
H
T
G
E
R
P
Y
K
C
Site 46
Y380
I
H
T
G
E
R
P
Y
K
C
K
Q
C
G
K
Site 47
Y394
K
A
F
R
S
S
N
Y
I
R
V
H
E
K
T
Site 48
T401
Y
I
R
V
H
E
K
T
H
T
G
E
K
P
Y
Site 49
T403
R
V
H
E
K
T
H
T
G
E
K
P
Y
E
C
Site 50
Y408
T
H
T
G
E
K
P
Y
E
C
K
Q
C
G
K
Site 51
S418
K
Q
C
G
K
A
L
S
H
L
K
S
F
Q
R
Site 52
S422
K
A
L
S
H
L
K
S
F
Q
R
H
M
I
M
Site 53
S444
K
C
K
I
C
G
K
S
F
D
S
P
S
S
F
Site 54
S447
I
C
G
K
S
F
D
S
P
S
S
F
R
R
H
Site 55
S449
G
K
S
F
D
S
P
S
S
F
R
R
H
E
R
Site 56
S450
K
S
F
D
S
P
S
S
F
R
R
H
E
R
I
Site 57
T459
R
R
H
E
R
I
H
T
G
E
R
P
Y
K
C
Site 58
Y464
I
H
T
G
E
R
P
Y
K
C
K
L
C
G
K
Site 59
S475
L
C
G
K
G
F
R
S
S
S
Y
I
Q
L
H
Site 60
S476
C
G
K
G
F
R
S
S
S
Y
I
Q
L
H
E
Site 61
S477
G
K
G
F
R
S
S
S
Y
I
Q
L
H
E
R
Site 62
Y478
K
G
F
R
S
S
S
Y
I
Q
L
H
E
R
T
Site 63
T487
Q
L
H
E
R
T
H
T
G
E
K
P
Y
G
C
Site 64
Y492
T
H
T
G
E
K
P
Y
G
C
Q
Q
C
G
K
Site 65
S502
Q
Q
C
G
K
A
L
S
D
L
S
S
F
R
R
Site 66
S505
G
K
A
L
S
D
L
S
S
F
R
R
H
M
I
Site 67
S506
K
A
L
S
D
L
S
S
F
R
R
H
M
I
T
Site 68
T513
S
F
R
R
H
M
I
T
H
T
G
N
G
P
H
Site 69
Y531
I
C
G
K
G
F
D
Y
P
S
S
V
Q
R
H
Site 70
S533
G
K
G
F
D
Y
P
S
S
V
Q
R
H
E
R
Site 71
S534
K
G
F
D
Y
P
S
S
V
Q
R
H
E
R
T
Site 72
T543
Q
R
H
E
R
T
H
T
G
E
K
P
Y
E
C
Site 73
Y548
T
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 74
S558
K
E
C
G
K
A
F
S
H
S
S
Y
L
R
I
Site 75
S560
C
G
K
A
F
S
H
S
S
Y
L
R
I
H
E
Site 76
S561
G
K
A
F
S
H
S
S
Y
L
R
I
H
E
R
Site 77
Y562
K
A
F
S
H
S
S
Y
L
R
I
H
E
R
V
Site 78
T571
R
I
H
E
R
V
H
T
G
E
K
P
Y
K
C
Site 79
Y576
V
H
T
G
E
K
P
Y
K
C
K
E
C
G
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation