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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANKFN1
Full Name:
Ankyrin repeat and fibronectin type-III domain-containing protein 1
Alias:
ANKF1; ankyrin repeat and fibronectin type-III domain-containing 1; ankyrin-repeat and fibronectin type III domain containing 1; FLJ38335
Type:
Unknown function
Mass (Da):
87620
Number AA:
UniProt ID:
Q8N957
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
E
A
S
L
T
R
R
L
L
F
K
D
Site 2
T17
L
F
K
D
R
H
F
T
C
S
K
I
I
G
R
Site 3
S34
A
C
F
A
Q
R
L
S
H
R
R
K
Q
S
Q
Site 4
S40
L
S
H
R
R
K
Q
S
Q
C
D
L
L
N
E
Site 5
T54
E
S
T
G
Q
L
P
T
T
C
S
S
A
A
S
Site 6
T55
S
T
G
Q
L
P
T
T
C
S
S
A
A
S
N
Site 7
S57
G
Q
L
P
T
T
C
S
S
A
A
S
N
S
I
Site 8
S58
Q
L
P
T
T
C
S
S
A
A
S
N
S
I
N
Site 9
S84
Q
N
L
H
L
C
Q
S
K
K
H
S
A
P
S
Site 10
S88
L
C
Q
S
K
K
H
S
A
P
S
S
P
N
A
Site 11
S92
K
K
H
S
A
P
S
S
P
N
A
A
K
R
L
Site 12
Y100
P
N
A
A
K
R
L
Y
R
N
L
S
E
K
L
Site 13
S104
K
R
L
Y
R
N
L
S
E
K
L
K
G
S
H
Site 14
S110
L
S
E
K
L
K
G
S
H
S
S
F
D
E
A
Site 15
S112
E
K
L
K
G
S
H
S
S
F
D
E
A
Y
F
Site 16
S113
K
L
K
G
S
H
S
S
F
D
E
A
Y
F
R
Site 17
Y118
H
S
S
F
D
E
A
Y
F
R
T
R
T
D
R
Site 18
T123
E
A
Y
F
R
T
R
T
D
R
L
S
L
R
K
Site 19
S127
R
T
R
T
D
R
L
S
L
R
K
T
S
V
N
Site 20
T131
D
R
L
S
L
R
K
T
S
V
N
F
Q
G
N
Site 21
S132
R
L
S
L
R
K
T
S
V
N
F
Q
G
N
E
Site 22
Y158
D
A
V
Q
I
L
L
Y
Q
Y
T
P
E
E
L
Site 23
T161
Q
I
L
L
Y
Q
Y
T
P
E
E
L
D
L
N
Site 24
T169
P
E
E
L
D
L
N
T
P
N
S
E
G
L
T
Site 25
S172
L
D
L
N
T
P
N
S
E
G
L
T
P
L
D
Site 26
T196
I
A
R
I
L
L
R
T
G
A
R
E
S
P
H
Site 27
S201
L
R
T
G
A
R
E
S
P
H
F
V
S
L
E
Site 28
S206
R
E
S
P
H
F
V
S
L
E
S
R
A
M
H
Site 29
S209
P
H
F
V
S
L
E
S
R
A
M
H
L
N
T
Site 30
S226
Q
E
A
Q
E
R
V
S
E
L
S
A
Q
V
E
Site 31
S229
Q
E
R
V
S
E
L
S
A
Q
V
E
N
E
G
Site 32
T242
E
G
F
T
L
D
N
T
E
K
E
K
Q
L
K
Site 33
Y255
L
K
A
W
E
W
R
Y
R
L
Y
R
R
M
K
Site 34
Y258
W
E
W
R
Y
R
L
Y
R
R
M
K
T
G
F
Site 35
T263
R
L
Y
R
R
M
K
T
G
F
E
H
A
R
A
Site 36
S310
T
R
Y
K
V
E
W
S
M
S
E
D
F
S
P
Site 37
S312
Y
K
V
E
W
S
M
S
E
D
F
S
P
L
A
Site 38
Y350
Y
F
V
Q
V
S
A
Y
N
M
K
G
W
G
P
Site 39
T360
K
G
W
G
P
A
Q
T
T
T
P
A
C
A
S
Site 40
T362
W
G
P
A
Q
T
T
T
P
A
C
A
S
P
S
Site 41
S367
T
T
T
P
A
C
A
S
P
S
N
W
K
D
Y
Site 42
Y374
S
P
S
N
W
K
D
Y
D
D
R
E
P
R
H
Site 43
S385
E
P
R
H
K
G
Q
S
E
V
L
E
G
L
L
Site 44
Y402
V
R
A
L
H
Q
H
Y
S
C
R
E
S
T
K
Site 45
S403
R
A
L
H
Q
H
Y
S
C
R
E
S
T
K
L
Site 46
S407
Q
H
Y
S
C
R
E
S
T
K
L
Q
T
T
G
Site 47
T408
H
Y
S
C
R
E
S
T
K
L
Q
T
T
G
R
Site 48
T413
E
S
T
K
L
Q
T
T
G
R
K
Q
S
V
S
Site 49
S418
Q
T
T
G
R
K
Q
S
V
S
R
S
L
K
H
Site 50
S420
T
G
R
K
Q
S
V
S
R
S
L
K
H
L
F
Site 51
S422
R
K
Q
S
V
S
R
S
L
K
H
L
F
H
S
Site 52
S429
S
L
K
H
L
F
H
S
S
N
K
F
V
K
T
Site 53
S430
L
K
H
L
F
H
S
S
N
K
F
V
K
T
L
Site 54
T436
S
S
N
K
F
V
K
T
L
K
R
G
L
Y
I
Site 55
S469
P
I
V
E
I
D
D
S
H
T
S
S
I
T
Q
Site 56
S473
I
D
D
S
H
T
S
S
I
T
Q
D
F
L
W
Site 57
S497
D
I
R
W
L
R
Q
S
I
P
I
S
S
S
S
Site 58
S502
R
Q
S
I
P
I
S
S
S
S
S
T
V
L
Q
Site 59
S503
Q
S
I
P
I
S
S
S
S
S
T
V
L
Q
T
Site 60
S504
S
I
P
I
S
S
S
S
S
T
V
L
Q
T
R
Site 61
S505
I
P
I
S
S
S
S
S
T
V
L
Q
T
R
Q
Site 62
T506
P
I
S
S
S
S
S
T
V
L
Q
T
R
Q
K
Site 63
Y534
T
H
N
L
G
R
V
Y
Y
E
P
I
K
D
R
Site 64
Y535
H
N
L
G
R
V
Y
Y
E
P
I
K
D
R
H
Site 65
Y557
I
R
E
V
E
M
L
Y
S
F
F
N
G
K
W
Site 66
S568
N
G
K
W
M
Q
I
S
K
L
Q
S
Q
R
K
Site 67
S572
M
Q
I
S
K
L
Q
S
Q
R
K
S
L
S
T
Site 68
S576
K
L
Q
S
Q
R
K
S
L
S
T
P
E
E
P
Site 69
S578
Q
S
Q
R
K
S
L
S
T
P
E
E
P
T
A
Site 70
T579
S
Q
R
K
S
L
S
T
P
E
E
P
T
A
L
Site 71
Y599
T
I
Q
D
I
L
S
Y
H
K
R
S
H
Q
R
Site 72
S660
W
E
W
I
Q
K
L
S
G
S
E
S
M
E
S
Site 73
S662
W
I
Q
K
L
S
G
S
E
S
M
E
S
V
D
Site 74
S664
Q
K
L
S
G
S
E
S
M
E
S
V
D
H
T
Site 75
S667
S
G
S
E
S
M
E
S
V
D
H
T
S
D
C
Site 76
T671
S
M
E
S
V
D
H
T
S
D
C
P
M
Q
L
Site 77
Y707
Q
A
R
N
F
R
L
Y
T
Q
E
V
L
E
M
Site 78
T708
A
R
N
F
R
L
Y
T
Q
E
V
L
E
M
G
Site 79
T732
P
A
S
D
D
V
C
T
A
P
G
Q
N
N
P
Site 80
Y740
A
P
G
Q
N
N
P
Y
T
P
H
S
G
F
L
Site 81
T741
P
G
Q
N
N
P
Y
T
P
H
S
G
F
L
N
Site 82
S744
N
N
P
Y
T
P
H
S
G
F
L
N
L
P
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation