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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF709
Full Name:
Zinc finger protein 709
Alias:
Type:
Nucleus protein
Mass (Da):
74652
Number AA:
641
UniProt ID:
Q8N972
International Prot ID:
IPI00640218
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
E
W
A
L
L
G
P
S
Q
K
K
L
Y
R
D
Site 2
Y29
G
P
S
Q
K
K
L
Y
R
D
V
M
Q
E
T
Site 3
S77
L
C
E
R
K
E
G
S
Q
F
G
E
T
I
S
Site 4
T82
E
G
S
Q
F
G
E
T
I
S
Q
T
P
N
P
Site 5
S84
S
Q
F
G
E
T
I
S
Q
T
P
N
P
K
P
Site 6
T86
F
G
E
T
I
S
Q
T
P
N
P
K
P
N
K
Site 7
T95
N
P
K
P
N
K
K
T
F
T
R
V
K
P
Y
Site 8
Y102
T
F
T
R
V
K
P
Y
E
C
S
V
C
G
K
Site 9
Y111
C
S
V
C
G
K
D
Y
M
C
H
S
S
L
N
Site 10
S123
S
L
N
R
H
M
R
S
H
T
E
H
R
S
Y
Site 11
T125
N
R
H
M
R
S
H
T
E
H
R
S
Y
E
Y
Site 12
Y130
S
H
T
E
H
R
S
Y
E
Y
H
K
Y
G
E
Site 13
Y135
R
S
Y
E
Y
H
K
Y
G
E
K
S
Y
E
C
Site 14
Y140
H
K
Y
G
E
K
S
Y
E
C
K
E
C
G
K
Site 15
S150
K
E
C
G
K
R
F
S
F
R
S
S
F
R
I
Site 16
S153
G
K
R
F
S
F
R
S
S
F
R
I
H
E
R
Site 17
S154
K
R
F
S
F
R
S
S
F
R
I
H
E
R
T
Site 18
T161
S
F
R
I
H
E
R
T
H
T
G
E
K
P
Y
Site 19
T163
R
I
H
E
R
T
H
T
G
E
K
P
Y
K
C
Site 20
S178
K
Q
C
G
K
A
F
S
W
P
S
S
F
Q
I
Site 21
S182
K
A
F
S
W
P
S
S
F
Q
I
H
E
R
T
Site 22
T189
S
F
Q
I
H
E
R
T
H
T
G
E
K
P
Y
Site 23
T191
Q
I
H
E
R
T
H
T
G
E
K
P
Y
E
C
Site 24
Y196
T
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 25
Y207
E
C
G
K
A
F
I
Y
H
T
T
F
R
G
H
Site 26
T219
R
G
H
M
R
M
H
T
G
E
K
P
Y
K
C
Site 27
T232
K
C
K
E
C
G
K
T
F
S
H
P
S
S
F
Site 28
S234
K
E
C
G
K
T
F
S
H
P
S
S
F
R
N
Site 29
S237
G
K
T
F
S
H
P
S
S
F
R
N
H
E
R
Site 30
S238
K
T
F
S
H
P
S
S
F
R
N
H
E
R
T
Site 31
T245
S
F
R
N
H
E
R
T
H
S
G
E
K
P
Y
Site 32
S247
R
N
H
E
R
T
H
S
G
E
K
P
Y
E
C
Site 33
Y252
T
H
S
G
E
K
P
Y
E
C
K
Q
C
G
K
Site 34
Y264
C
G
K
A
F
R
Y
Y
Q
T
F
Q
I
H
E
Site 35
T273
T
F
Q
I
H
E
R
T
H
T
G
E
K
P
Y
Site 36
T275
Q
I
H
E
R
T
H
T
G
E
K
P
Y
Q
C
Site 37
Y280
T
H
T
G
E
K
P
Y
Q
C
K
Q
C
G
K
Site 38
S290
K
Q
C
G
K
A
L
S
C
P
T
S
F
R
S
Site 39
T293
G
K
A
L
S
C
P
T
S
F
R
S
H
E
R
Site 40
S294
K
A
L
S
C
P
T
S
F
R
S
H
E
R
I
Site 41
S297
S
C
P
T
S
F
R
S
H
E
R
I
H
T
G
Site 42
T303
R
S
H
E
R
I
H
T
G
E
K
P
Y
K
C
Site 43
S318
K
K
C
G
K
A
F
S
F
P
S
S
F
R
K
Site 44
S321
G
K
A
F
S
F
P
S
S
F
R
K
H
E
R
Site 45
S322
K
A
F
S
F
P
S
S
F
R
K
H
E
R
I
Site 46
T331
R
K
H
E
R
I
H
T
G
E
K
P
Y
D
C
Site 47
Y336
I
H
T
G
E
K
P
Y
D
C
K
E
C
G
K
Site 48
S347
E
C
G
K
A
F
I
S
L
P
S
Y
R
R
H
Site 49
Y351
A
F
I
S
L
P
S
Y
R
R
H
M
I
M
H
Site 50
Y364
M
H
T
G
N
G
P
Y
K
C
K
E
C
G
K
Site 51
S377
G
K
A
F
D
C
P
S
S
F
Q
I
H
E
R
Site 52
S378
K
A
F
D
C
P
S
S
F
Q
I
H
E
R
T
Site 53
Y392
T
H
T
G
E
K
P
Y
E
C
K
Q
C
G
K
Site 54
S402
K
Q
C
G
K
A
F
S
C
S
S
S
F
R
M
Site 55
S404
C
G
K
A
F
S
C
S
S
S
F
R
M
H
E
Site 56
S405
G
K
A
F
S
C
S
S
S
F
R
M
H
E
R
Site 57
S406
K
A
F
S
C
S
S
S
F
R
M
H
E
R
T
Site 58
T413
S
F
R
M
H
E
R
T
H
T
G
E
K
P
H
Site 59
T415
R
M
H
E
R
T
H
T
G
E
K
P
H
E
C
Site 60
S430
K
Q
C
G
K
A
F
S
C
S
S
S
V
R
I
Site 61
S432
C
G
K
A
F
S
C
S
S
S
V
R
I
H
E
Site 62
S433
G
K
A
F
S
C
S
S
S
V
R
I
H
E
R
Site 63
S434
K
A
F
S
C
S
S
S
V
R
I
H
E
R
T
Site 64
T441
S
V
R
I
H
E
R
T
H
T
G
E
K
P
Y
Site 65
T443
R
I
H
E
R
T
H
T
G
E
K
P
Y
E
C
Site 66
S462
K
A
F
S
C
S
S
S
F
R
M
H
E
R
I
Site 67
T471
R
M
H
E
R
I
H
T
G
E
K
P
Y
E
C
Site 68
Y476
I
H
T
G
E
K
P
Y
E
C
K
Q
C
G
K
Site 69
S486
K
Q
C
G
K
A
F
S
F
S
S
S
F
R
M
Site 70
S488
C
G
K
A
F
S
F
S
S
S
F
R
M
H
E
Site 71
S489
G
K
A
F
S
F
S
S
S
F
R
M
H
E
R
Site 72
S490
K
A
F
S
F
S
S
S
F
R
M
H
E
R
T
Site 73
T497
S
F
R
M
H
E
R
T
H
T
G
E
K
P
Y
Site 74
T499
R
M
H
E
R
T
H
T
G
E
K
P
Y
E
C
Site 75
S542
K
Q
C
G
K
A
F
S
C
S
S
S
I
R
I
Site 76
S544
C
G
K
A
F
S
C
S
S
S
I
R
I
H
E
Site 77
S545
G
K
A
F
S
C
S
S
S
I
R
I
H
E
R
Site 78
S546
K
A
F
S
C
S
S
S
I
R
I
H
E
R
T
Site 79
T553
S
I
R
I
H
E
R
T
H
T
G
E
K
P
Y
Site 80
S570
K
Q
C
G
K
A
F
S
C
S
S
S
V
R
M
Site 81
S572
C
G
K
A
F
S
C
S
S
S
V
R
M
H
E
Site 82
S573
G
K
A
F
S
C
S
S
S
V
R
M
H
E
R
Site 83
S574
K
A
F
S
C
S
S
S
V
R
M
H
E
R
T
Site 84
T581
S
V
R
M
H
E
R
T
H
T
G
V
K
P
Y
Site 85
T583
R
M
H
E
R
T
H
T
G
V
K
P
Y
E
C
Site 86
S598
K
Q
C
D
K
A
F
S
C
S
R
S
F
R
I
Site 87
S602
K
A
F
S
C
S
R
S
F
R
I
H
E
R
T
Site 88
T611
R
I
H
E
R
T
H
T
G
E
K
P
Y
A
C
Site 89
Y616
T
H
T
G
E
K
P
Y
A
C
Q
Q
C
G
K
Site 90
S630
K
A
F
K
C
S
R
S
F
R
I
H
E
R
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation