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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF557
Full Name:
Zinc finger protein 557
Alias:
Type:
Mass (Da):
48627
Number AA:
423
UniProt ID:
Q8N988
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
V
L
P
P
T
A
A
S
Q
R
E
G
H
T
E
Site 2
Y61
D
P
A
Q
R
T
L
Y
R
D
V
M
L
E
N
Site 3
S86
V
D
K
P
R
L
I
S
Q
L
E
Q
E
D
K
Site 4
T119
P
F
K
A
K
G
L
T
P
K
L
H
V
F
R
Site 5
T143
E
R
N
H
L
G
A
T
L
N
E
C
N
Q
C
Site 6
S155
N
Q
C
F
K
V
F
S
T
K
S
S
L
T
R
Site 7
S158
F
K
V
F
S
T
K
S
S
L
T
R
H
R
K
Site 8
S159
K
V
F
S
T
K
S
S
L
T
R
H
R
K
I
Site 9
Y173
I
H
T
G
E
R
P
Y
G
C
S
E
C
G
K
Site 10
S176
G
E
R
P
Y
G
C
S
E
C
G
K
S
Y
S
Site 11
S181
G
C
S
E
C
G
K
S
Y
S
S
R
S
Y
L
Site 12
Y182
C
S
E
C
G
K
S
Y
S
S
R
S
Y
L
A
Site 13
S183
S
E
C
G
K
S
Y
S
S
R
S
Y
L
A
V
Site 14
S184
E
C
G
K
S
Y
S
S
R
S
Y
L
A
V
H
Site 15
S186
G
K
S
Y
S
S
R
S
Y
L
A
V
H
K
R
Site 16
Y187
K
S
Y
S
S
R
S
Y
L
A
V
H
K
R
I
Site 17
Y201
I
H
N
G
E
K
P
Y
E
C
N
D
C
G
K
Site 18
T209
E
C
N
D
C
G
K
T
F
S
S
R
S
Y
L
Site 19
S211
N
D
C
G
K
T
F
S
S
R
S
Y
L
T
V
Site 20
S214
G
K
T
F
S
S
R
S
Y
L
T
V
H
K
R
Site 21
Y215
K
T
F
S
S
R
S
Y
L
T
V
H
K
R
I
Site 22
T217
F
S
S
R
S
Y
L
T
V
H
K
R
I
H
N
Site 23
Y229
I
H
N
G
E
K
P
Y
E
C
S
D
C
G
K
Site 24
S232
G
E
K
P
Y
E
C
S
D
C
G
K
T
F
S
Site 25
T237
E
C
S
D
C
G
K
T
F
S
N
S
S
Y
L
Site 26
S239
S
D
C
G
K
T
F
S
N
S
S
Y
L
R
P
Site 27
S241
C
G
K
T
F
S
N
S
S
Y
L
R
P
H
L
Site 28
S242
G
K
T
F
S
N
S
S
Y
L
R
P
H
L
R
Site 29
Y243
K
T
F
S
N
S
S
Y
L
R
P
H
L
R
I
Site 30
T252
R
P
H
L
R
I
H
T
G
E
K
P
Y
K
C
Site 31
S270
F
R
E
F
R
T
Q
S
I
F
T
R
H
K
R
Site 32
T280
T
R
H
K
R
V
H
T
G
E
G
H
Y
V
C
Site 33
Y285
V
H
T
G
E
G
H
Y
V
C
N
Q
C
G
K
Site 34
T296
Q
C
G
K
A
F
G
T
R
S
S
L
S
S
H
Site 35
S298
G
K
A
F
G
T
R
S
S
L
S
S
H
Y
S
Site 36
S299
K
A
F
G
T
R
S
S
L
S
S
H
Y
S
I
Site 37
S301
F
G
T
R
S
S
L
S
S
H
Y
S
I
H
T
Site 38
S302
G
T
R
S
S
L
S
S
H
Y
S
I
H
T
G
Site 39
S305
S
S
L
S
S
H
Y
S
I
H
T
G
E
Y
P
Site 40
Y313
I
H
T
G
E
Y
P
Y
E
C
H
D
C
G
R
Site 41
T321
E
C
H
D
C
G
R
T
F
R
R
R
S
N
L
Site 42
S326
G
R
T
F
R
R
R
S
N
L
T
Q
H
I
R
Site 43
T329
F
R
R
R
S
N
L
T
Q
H
I
R
T
H
T
Site 44
T334
N
L
T
Q
H
I
R
T
H
T
G
E
K
P
Y
Site 45
T336
T
Q
H
I
R
T
H
T
G
E
K
P
Y
T
C
Site 46
Y341
T
H
T
G
E
K
P
Y
T
C
N
E
C
G
K
Site 47
T342
H
T
G
E
K
P
Y
T
C
N
E
C
G
K
S
Site 48
S349
T
C
N
E
C
G
K
S
F
T
N
S
F
S
L
Site 49
T351
N
E
C
G
K
S
F
T
N
S
F
S
L
T
I
Site 50
S353
C
G
K
S
F
T
N
S
F
S
L
T
I
H
R
Site 51
S355
K
S
F
T
N
S
F
S
L
T
I
H
R
R
I
Site 52
Y369
I
H
N
G
E
K
S
Y
E
C
S
D
C
G
K
Site 53
S372
G
E
K
S
Y
E
C
S
D
C
G
K
S
F
N
Site 54
S377
E
C
S
D
C
G
K
S
F
N
V
L
S
S
V
Site 55
S382
G
K
S
F
N
V
L
S
S
V
K
K
H
M
R
Site 56
S383
K
S
F
N
V
L
S
S
V
K
K
H
M
R
T
Site 57
T390
S
V
K
K
H
M
R
T
H
T
G
K
K
P
Y
Site 58
T392
K
K
H
M
R
T
H
T
G
K
K
P
Y
E
C
Site 59
Y397
T
H
T
G
K
K
P
Y
E
C
N
Y
C
G
K
Site 60
Y401
K
K
P
Y
E
C
N
Y
C
G
K
S
F
T
S
Site 61
S405
E
C
N
Y
C
G
K
S
F
T
S
N
S
Y
L
Site 62
S408
Y
C
G
K
S
F
T
S
N
S
Y
L
S
V
H
Site 63
S410
G
K
S
F
T
S
N
S
Y
L
S
V
H
T
R
Site 64
Y411
K
S
F
T
S
N
S
Y
L
S
V
H
T
R
M
Site 65
S413
F
T
S
N
S
Y
L
S
V
H
T
R
M
H
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation