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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RASGEF1A
Full Name:
Ras-GEF domain-containing family member 1A
Alias:
Type:
Mass (Da):
54556
Number AA:
481
UniProt ID:
Q8N9B8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
F
S
S
I
L
G
P
S
C
S
G
Q
V
Q
P
Site 2
S35
G
G
G
A
G
G
G
S
G
D
L
I
F
Q
D
Site 3
S49
D
G
H
L
I
S
G
S
L
E
A
L
M
E
H
Site 4
T60
L
M
E
H
L
V
P
T
V
D
Y
Y
P
D
R
Site 5
Y63
H
L
V
P
T
V
D
Y
Y
P
D
R
T
Y
I
Site 6
Y64
L
V
P
T
V
D
Y
Y
P
D
R
T
Y
I
F
Site 7
Y69
D
Y
Y
P
D
R
T
Y
I
F
T
F
L
L
S
Site 8
S112
P
E
K
A
K
L
K
S
F
S
A
K
I
V
Q
Site 9
Y130
E
W
T
E
A
F
P
Y
D
F
Q
D
E
K
A
Site 10
T149
K
A
I
T
H
R
V
T
Q
C
D
E
E
N
G
Site 11
T157
Q
C
D
E
E
N
G
T
V
K
K
A
I
A
Q
Site 12
T199
D
K
G
P
I
L
K
T
K
P
P
A
A
Q
K
Site 13
S231
H
I
E
L
D
R
V
S
S
I
Y
P
E
D
L
Site 14
S232
I
E
L
D
R
V
S
S
I
Y
P
E
D
L
M
Site 15
Y234
L
D
R
V
S
S
I
Y
P
E
D
L
M
Q
I
Site 16
S243
E
D
L
M
Q
I
V
S
H
M
D
S
L
D
N
Site 17
T258
H
R
C
R
G
D
L
T
K
T
Y
S
L
E
A
Site 18
T260
C
R
G
D
L
T
K
T
Y
S
L
E
A
Y
D
Site 19
S262
G
D
L
T
K
T
Y
S
L
E
A
Y
D
N
W
Site 20
Y266
K
T
Y
S
L
E
A
Y
D
N
W
F
N
C
L
Site 21
S333
A
R
L
K
K
T
W
S
K
V
K
T
A
K
F
Site 22
T337
K
T
W
S
K
V
K
T
A
K
F
D
V
L
E
Site 23
T364
R
T
A
L
Q
G
A
T
Q
R
S
Q
M
A
N
Site 24
S367
L
Q
G
A
T
Q
R
S
Q
M
A
N
S
S
R
Site 25
S372
Q
R
S
Q
M
A
N
S
S
R
E
K
I
V
I
Site 26
S373
R
S
Q
M
A
N
S
S
R
E
K
I
V
I
P
Site 27
Y439
K
D
K
K
I
Q
S
Y
L
L
T
A
P
I
Y
Site 28
T442
K
I
Q
S
Y
L
L
T
A
P
I
Y
S
E
E
Site 29
S455
E
E
A
L
F
V
A
S
F
E
S
E
G
P
E
Site 30
T472
M
E
K
D
S
W
K
T
L
R
T
T
L
L
N
Site 31
T476
S
W
K
T
L
R
T
T
L
L
N
R
A
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation