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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SYT2
Full Name:
Synaptotagmin-2
Alias:
Synaptotagmin II; SytII
Type:
Vesicle protein
Mass (Da):
46872
Number AA:
419
UniProt ID:
Q8N9I0
International Prot ID:
IPI00219274
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0030666
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
GO:0005215
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S30
P
I
G
P
V
D
N
S
T
E
S
G
G
A
G
Site 2
T31
I
G
P
V
D
N
S
T
E
S
G
G
A
G
E
Site 3
S39
E
S
G
G
A
G
E
S
Q
E
D
M
F
A
K
Site 4
T122
Q
D
D
D
D
A
E
T
G
L
T
E
G
E
G
Site 5
T125
D
D
A
E
T
G
L
T
E
G
E
G
E
G
E
Site 6
S146
N
L
G
K
L
Q
F
S
L
D
Y
D
F
Q
A
Site 7
Y149
K
L
Q
F
S
L
D
Y
D
F
Q
A
N
Q
L
Site 8
Y191
L
P
D
K
K
K
K
Y
E
T
K
V
H
R
K
Site 9
T199
E
T
K
V
H
R
K
T
L
N
P
A
F
N
E
Site 10
T207
L
N
P
A
F
N
E
T
F
T
F
K
V
P
Y
Site 11
T209
P
A
F
N
E
T
F
T
F
K
V
P
Y
Q
E
Site 12
Y214
T
F
T
F
K
V
P
Y
Q
E
L
G
G
K
T
Site 13
Y227
K
T
L
V
M
A
I
Y
D
F
D
R
F
S
K
Site 14
T276
E
K
L
G
D
I
C
T
S
L
R
Y
V
P
T
Site 15
S306
K
M
D
V
G
G
L
S
D
P
Y
V
K
I
H
Site 16
Y309
V
G
G
L
S
D
P
Y
V
K
I
H
L
M
Q
Site 17
T326
K
R
L
K
K
K
K
T
T
V
K
K
K
T
L
Site 18
T332
K
T
T
V
K
K
K
T
L
N
P
Y
F
N
E
Site 19
Y336
K
K
K
T
L
N
P
Y
F
N
E
S
F
S
F
Site 20
S340
L
N
P
Y
F
N
E
S
F
S
F
E
I
P
F
Site 21
S342
P
Y
F
N
E
S
F
S
F
E
I
P
F
E
Q
Site 22
Y362
V
V
V
T
V
L
D
Y
D
K
L
G
K
N
E
Site 23
T383
V
G
S
N
A
T
G
T
E
L
R
H
W
S
D
Site 24
S389
G
T
E
L
R
H
W
S
D
M
L
A
N
P
R
Site 25
S404
R
P
I
A
Q
W
H
S
L
K
P
E
E
E
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation