KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZIC4
Full Name:
Zinc finger protein ZIC 4
Alias:
Zinc finger protein of the cerebellum 4
Type:
Mass (Da):
36567
Number AA:
334
UniProt ID:
Q8N9L1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
M
R
K
R
L
R
L
Y
R
N
T
L
K
E
S
Site 2
T19
R
L
R
L
Y
R
N
T
L
K
E
S
S
S
S
Site 3
S23
Y
R
N
T
L
K
E
S
S
S
S
S
G
H
H
Site 4
S24
R
N
T
L
K
E
S
S
S
S
S
G
H
H
G
Site 5
S25
N
T
L
K
E
S
S
S
S
S
G
H
H
G
P
Site 6
S26
T
L
K
E
S
S
S
S
S
G
H
H
G
P
Q
Site 7
S27
L
K
E
S
S
S
S
S
G
H
H
G
P
Q
L
Site 8
T35
G
H
H
G
P
Q
L
T
A
A
S
S
P
S
V
Site 9
S38
G
P
Q
L
T
A
A
S
S
P
S
V
F
P
G
Site 10
S54
H
E
E
P
P
Q
A
S
P
S
R
P
L
N
G
Site 11
S56
E
P
P
Q
A
S
P
S
R
P
L
N
G
L
L
Site 12
Y72
L
G
L
P
G
D
M
Y
A
R
P
E
P
F
P
Site 13
Y119
G
P
G
A
F
F
R
Y
M
R
Q
P
I
K
Q
Site 14
S142
A
D
G
T
A
T
P
S
L
C
S
K
T
F
S
Site 15
S145
T
A
T
P
S
L
C
S
K
T
F
S
T
M
H
Site 16
T147
T
P
S
L
C
S
K
T
F
S
T
M
H
E
L
Site 17
T159
H
E
L
V
T
H
V
T
V
E
H
V
G
G
P
Site 18
Y189
G
K
P
F
K
A
K
Y
K
L
V
N
H
I
R
Site 19
T199
V
N
H
I
R
V
H
T
G
E
K
P
F
P
C
Site 20
S218
C
G
K
V
F
A
R
S
E
N
L
K
I
H
K
Site 21
T227
N
L
K
I
H
K
R
T
H
T
G
E
K
P
F
Site 22
T229
K
I
H
K
R
T
H
T
G
E
K
P
F
R
C
Site 23
S248
C
E
R
R
F
A
N
S
S
D
R
K
K
H
S
Site 24
S249
E
R
R
F
A
N
S
S
D
R
K
K
H
S
H
Site 25
S255
S
S
D
R
K
K
H
S
H
V
H
T
S
D
K
Site 26
Y264
V
H
T
S
D
K
P
Y
T
C
K
V
R
G
C
Site 27
Y275
V
R
G
C
D
K
C
Y
T
H
P
S
S
L
R
Site 28
T276
R
G
C
D
K
C
Y
T
H
P
S
S
L
R
K
Site 29
S280
K
C
Y
T
H
P
S
S
L
R
K
H
M
K
V
Site 30
S291
H
M
K
V
H
G
R
S
P
P
P
S
S
G
Y
Site 31
S295
H
G
R
S
P
P
P
S
S
G
Y
D
S
A
T
Site 32
S296
G
R
S
P
P
P
S
S
G
Y
D
S
A
T
P
Site 33
Y298
S
P
P
P
S
S
G
Y
D
S
A
T
P
S
A
Site 34
S300
P
P
S
S
G
Y
D
S
A
T
P
S
A
L
V
Site 35
T302
S
S
G
Y
D
S
A
T
P
S
A
L
V
S
P
Site 36
S304
G
Y
D
S
A
T
P
S
A
L
V
S
P
S
S
Site 37
S308
A
T
P
S
A
L
V
S
P
S
S
D
C
G
H
Site 38
S310
P
S
A
L
V
S
P
S
S
D
C
G
H
K
S
Site 39
S311
S
A
L
V
S
P
S
S
D
C
G
H
K
S
Q
Site 40
S317
S
S
D
C
G
H
K
S
Q
V
A
S
S
A
A
Site 41
S321
G
H
K
S
Q
V
A
S
S
A
A
V
A
A
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation