KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ASCC1
Full Name:
Activating signal cointegrator 1 complex subunit 1
Alias:
Activating signal cointegrator 1 complex 1; ASC-1 complex p50; ASC-1 complex subunit p50; ASC1p50; CGI-18; Em:AC022392.3; Trip4 complex p50; Trip4 complex subunit p50
Type:
Mass (Da):
45509
Number AA:
400
UniProt ID:
Q8N9N2
International Prot ID:
IPI00434389
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005667
Uniprot
OncoNet
Molecular Function:
GO:0003723
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
I
R
I
D
G
R
N
Y
R
K
N
P
V
Q
E
Site 2
T25
K
N
P
V
Q
E
Q
T
Y
Q
H
E
E
D
E
Site 3
Y36
E
E
D
E
E
D
F
Y
Q
G
S
M
E
C
A
Site 4
S39
E
E
D
F
Y
Q
G
S
M
E
C
A
D
E
P
Site 5
Y50
A
D
E
P
C
D
A
Y
E
V
E
Q
T
P
Q
Site 6
T55
D
A
Y
E
V
E
Q
T
P
Q
G
F
R
S
T
Site 7
S61
Q
T
P
Q
G
F
R
S
T
L
R
A
P
S
L
Site 8
T62
T
P
Q
G
F
R
S
T
L
R
A
P
S
L
L
Site 9
S67
R
S
T
L
R
A
P
S
L
L
Y
N
L
I
H
Site 10
Y94
T
L
D
C
Q
N
I
Y
T
W
K
S
R
H
I
Site 11
T108
I
V
G
K
R
G
D
T
R
K
K
I
E
M
E
Site 12
T118
K
I
E
M
E
T
K
T
S
I
S
I
P
K
P
Site 13
S119
I
E
M
E
T
K
T
S
I
S
I
P
K
P
G
Site 14
S121
M
E
T
K
T
S
I
S
I
P
K
P
G
Q
D
Site 15
T134
Q
D
G
E
I
V
I
T
G
Q
H
R
N
G
V
Site 16
S143
Q
H
R
N
G
V
I
S
A
R
T
R
I
D
V
Site 17
T154
R
I
D
V
L
L
D
T
F
R
R
K
Q
P
F
Site 18
S197
S
M
D
H
G
V
D
S
S
I
F
Q
N
P
K
Site 19
S198
M
D
H
G
V
D
S
S
I
F
Q
N
P
K
K
Site 20
T224
S
E
E
E
I
Q
Q
T
C
E
M
L
Q
Q
C
Site 21
S240
E
E
F
I
N
D
I
S
G
G
K
P
L
E
V
Site 22
Y254
V
E
M
A
G
I
E
Y
M
N
D
D
P
G
M
Site 23
Y266
P
G
M
V
D
V
L
Y
A
K
V
H
M
K
D
Site 24
S275
K
V
H
M
K
D
G
S
N
R
L
Q
E
L
V
Site 25
Y326
A
E
G
R
Y
N
L
Y
T
A
E
G
K
Y
I
Site 26
T327
E
G
R
Y
N
L
Y
T
A
E
G
K
Y
I
F
Site 27
S339
Y
I
F
K
E
R
E
S
F
D
G
R
N
I
L
Site 28
Y357
A
L
L
P
R
L
E
Y
N
D
A
I
S
A
H
Site 29
S372
C
N
L
C
L
P
G
S
S
D
S
P
A
S
A
Site 30
S373
N
L
C
L
P
G
S
S
D
S
P
A
S
A
S
Site 31
S375
C
L
P
G
S
S
D
S
P
A
S
A
S
Q
V
Site 32
S378
G
S
S
D
S
P
A
S
A
S
Q
V
A
G
I
Site 33
S380
S
D
S
P
A
S
A
S
Q
V
A
G
I
T
G
Site 34
Y392
I
T
G
V
S
D
A
Y
S
Q
S
L
P
G
K
Site 35
S393
T
G
V
S
D
A
Y
S
Q
S
L
P
G
K
S
Site 36
S395
V
S
D
A
Y
S
Q
S
L
P
G
K
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation