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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MTAC2D1
Full Name:
Tandem C2 domains nuclear protein
Alias:
C14_5695; C14orf47; C2 calcium-dependent domain containing 1; C2CD1; FLJ36557; Membrane targeting (tandem) C2 domain containing 1; Membrane targeting tandem C2 domain-containing 1; TAC2N; Tac2-N; Tandem C2 domains, nuclear; Tandem C2 protein in nucleus
Type:
Mass (Da):
55260
Number AA:
UniProt ID:
Q8N9U0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
E
T
E
K
H
N
F
S
V
E
R
D
F
K
A
Site 2
T40
V
P
N
S
Q
N
A
T
I
S
V
P
P
L
T
Site 3
S42
N
S
Q
N
A
T
I
S
V
P
P
L
T
S
V
Site 4
Y61
Q
L
G
C
T
E
D
Y
L
L
S
K
L
P
S
Site 5
S64
C
T
E
D
Y
L
L
S
K
L
P
S
D
G
K
Site 6
S68
Y
L
L
S
K
L
P
S
D
G
K
E
V
P
F
Site 7
S83
V
V
P
K
F
K
L
S
Y
I
Q
P
R
T
Q
Site 8
Y84
V
P
K
F
K
L
S
Y
I
Q
P
R
T
Q
E
Site 9
T89
L
S
Y
I
Q
P
R
T
Q
E
T
P
S
H
L
Site 10
T92
I
Q
P
R
T
Q
E
T
P
S
H
L
E
E
L
Site 11
S94
P
R
T
Q
E
T
P
S
H
L
E
E
L
E
G
Site 12
S102
H
L
E
E
L
E
G
S
A
R
A
S
F
G
D
Site 13
S106
L
E
G
S
A
R
A
S
F
G
D
R
K
V
E
Site 14
S115
G
D
R
K
V
E
L
S
S
S
S
Q
H
G
P
Site 15
S116
D
R
K
V
E
L
S
S
S
S
Q
H
G
P
S
Site 16
S117
R
K
V
E
L
S
S
S
S
Q
H
G
P
S
Y
Site 17
S118
K
V
E
L
S
S
S
S
Q
H
G
P
S
Y
D
Site 18
S123
S
S
S
Q
H
G
P
S
Y
D
V
Y
N
P
F
Site 19
Y124
S
S
Q
H
G
P
S
Y
D
V
Y
N
P
F
Y
Site 20
Y127
H
G
P
S
Y
D
V
Y
N
P
F
Y
M
Y
Q
Site 21
Y131
Y
D
V
Y
N
P
F
Y
M
Y
Q
H
I
S
P
Site 22
Y133
V
Y
N
P
F
Y
M
Y
Q
H
I
S
P
D
L
Site 23
S137
F
Y
M
Y
Q
H
I
S
P
D
L
S
R
R
F
Site 24
S141
Q
H
I
S
P
D
L
S
R
R
F
P
P
R
S
Site 25
S148
S
R
R
F
P
P
R
S
E
V
T
R
L
Y
G
Site 26
Y154
R
S
E
V
T
R
L
Y
G
S
V
C
D
L
R
Site 27
S156
E
V
T
R
L
Y
G
S
V
C
D
L
R
T
N
Site 28
T162
G
S
V
C
D
L
R
T
N
K
L
P
G
S
P
Site 29
S168
R
T
N
K
L
P
G
S
P
G
L
S
K
S
M
Site 30
S172
L
P
G
S
P
G
L
S
K
S
M
F
D
L
T
Site 31
S174
G
S
P
G
L
S
K
S
M
F
D
L
T
N
S
Site 32
T179
S
K
S
M
F
D
L
T
N
S
S
Q
R
F
I
Site 33
S181
S
M
F
D
L
T
N
S
S
Q
R
F
I
Q
R
Site 34
S191
R
F
I
Q
R
H
D
S
L
S
S
V
P
S
S
Site 35
S193
I
Q
R
H
D
S
L
S
S
V
P
S
S
S
S
Site 36
S194
Q
R
H
D
S
L
S
S
V
P
S
S
S
S
S
Site 37
S197
D
S
L
S
S
V
P
S
S
S
S
S
R
K
N
Site 38
S198
S
L
S
S
V
P
S
S
S
S
S
R
K
N
S
Site 39
S199
L
S
S
V
P
S
S
S
S
S
R
K
N
S
Q
Site 40
S200
S
S
V
P
S
S
S
S
S
R
K
N
S
Q
G
Site 41
S201
S
V
P
S
S
S
S
S
R
K
N
S
Q
G
S
Site 42
S205
S
S
S
S
R
K
N
S
Q
G
S
N
R
S
L
Site 43
S208
S
R
K
N
S
Q
G
S
N
R
S
L
D
T
I
Site 44
S211
N
S
Q
G
S
N
R
S
L
D
T
I
T
L
S
Site 45
T214
G
S
N
R
S
L
D
T
I
T
L
S
G
D
E
Site 46
T216
N
R
S
L
D
T
I
T
L
S
G
D
E
R
D
Site 47
S218
S
L
D
T
I
T
L
S
G
D
E
R
D
F
G
Site 48
Y233
R
L
N
V
K
L
F
Y
N
S
S
V
E
Q
I
Site 49
S251
V
L
Q
C
R
D
L
S
W
P
S
S
Y
G
D
Site 50
S255
R
D
L
S
W
P
S
S
Y
G
D
T
P
T
V
Site 51
T259
W
P
S
S
Y
G
D
T
P
T
V
S
I
K
G
Site 52
T261
S
S
Y
G
D
T
P
T
V
S
I
K
G
I
L
Site 53
S278
P
K
P
V
H
F
K
S
S
A
K
E
G
S
N
Site 54
T313
R
L
V
F
K
I
Q
T
Q
T
P
R
K
K
T
Site 55
T315
V
F
K
I
Q
T
Q
T
P
R
K
K
T
I
G
Site 56
T320
T
Q
T
P
R
K
K
T
I
G
E
C
S
M
S
Site 57
S325
K
K
T
I
G
E
C
S
M
S
L
R
T
L
S
Site 58
S327
T
I
G
E
C
S
M
S
L
R
T
L
S
T
Q
Site 59
S332
S
M
S
L
R
T
L
S
T
Q
E
M
D
Y
S
Site 60
T333
M
S
L
R
T
L
S
T
Q
E
M
D
Y
S
L
Site 61
Y338
L
S
T
Q
E
M
D
Y
S
L
D
I
T
P
P
Site 62
S339
S
T
Q
E
M
D
Y
S
L
D
I
T
P
P
S
Site 63
T343
M
D
Y
S
L
D
I
T
P
P
S
K
I
S
V
Site 64
Y377
L
Q
I
L
E
A
R
Y
L
P
S
S
S
T
P
Site 65
S380
L
E
A
R
Y
L
P
S
S
S
T
P
L
T
L
Site 66
S381
E
A
R
Y
L
P
S
S
S
T
P
L
T
L
S
Site 67
S382
A
R
Y
L
P
S
S
S
T
P
L
T
L
S
F
Site 68
T383
R
Y
L
P
S
S
S
T
P
L
T
L
S
F
F
Site 69
S388
S
S
T
P
L
T
L
S
F
F
V
K
V
G
M
Site 70
S413
K
T
R
L
L
K
A
S
N
G
R
V
K
W
G
Site 71
S442
V
F
L
I
K
L
Y
S
R
S
S
V
R
R
K
Site 72
S444
L
I
K
L
Y
S
R
S
S
V
R
R
K
H
F
Site 73
S445
I
K
L
Y
S
R
S
S
V
R
R
K
H
F
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation